iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120005

Ensembl Protein ID

ENSTNIP00000020756.1

UniProt Accession

H3DJR0; H3DJR0_TETNG

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000017609.1	ENSTNIT00000020989.1	ENSTNIP00000020756.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.40e-15	55.6	66	123

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ v++ly+yea + d+L +kkG+ ++++   e+ ++W+++++  ++++G++P+n+v +++
   Q: 66   EKIVIALYPYEALHPDDLGFKKGERMKIL---EERGEWWRAKSLSTNREGFIPSNYVGQAD 123
           6899*************************...999**********************8875 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

AGRMGCIKSR LDGGVSKGVE EKSSPQTVRT QLARYVRDPT SDINHNINNS LLPGQRFQTL 60
EEKGVEKIVI ALYPYEALHP DDLGFKKGER MKILEERGEW WRAKSLSTNR EGFIPSNYVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGGCAGGA TGGGCTGCAT AAAGTCCAGA CTGGATGGAG GTGTGAGCAA AGGTGTGGAG 60
GAGAAGAGCA GCCCGCAGAC TGTACGTACT CAGCTAGCGC GTTATGTCAG AGACCCCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0090022--P:regulation of neutrophil chemotaxis
GO:0009611--P:response to wounding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	71.54	0.00e+00	776.00
IUUC-Apl-004139	Anas platyrhynchos	69.81	0.00e+00	757.00
IUUC-Aca-004333	Anolis carolinensis	71.79	0.00e+00	768.00
IUUC-Ame-011257	Astyanax mexicanus	78.06	0.00e+00	854.00
IUUC-Bta-013257	Bos taurus	71.15	0.00e+00	775.00
IUUC-Cja-018827	Callithrix jacchus	71.54	0.00e+00	776.00
IUUC-Cfa-020816	Canis familiaris	71.35	0.00e+00	776.00
IUUC-Cpo-021423	Cavia porcellus	71.15	0.00e+00	771.00
IUUC-Csa-024244	Chlorocebus sabaeus	70.96	0.00e+00	771.00
IUUC-Dre-028518	Danio rerio	78.60	0.00e+00	847.00
IUUC-Dno-029322	Dasypus novemcinctus	72.18	0.00e+00	775.00
IUUC-Dor-030706	Dipodomys ordii	65.18	0.00e+00	701.00
IUUC-Eca-034193	Equus caballus	71.73	0.00e+00	780.00
IUUC-Eeu-035004	Erinaceus europaeus	60.00	2.00e-137	481.00
IUUC-Fca-035937	Felis catus	64.05	0.00e+00	674.00
IUUC-Fal-037273	Ficedula albicollis	70.27	0.00e+00	772.00
IUUC-Gmo-039677	Gadus morhua	80.76	0.00e+00	773.00
IUUC-Gga-040417	Gallus gallus	68.81	0.00e+00	753.00
IUUC-Gac-042490	Gasterosteus aculeatus	81.09	0.00e+00	874.00
IUUC-Ggo-045096	Gorilla gorilla	71.35	0.00e+00	776.00
IUUC-Hsa-046214	Homo sapiens	71.35	0.00e+00	776.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	71.54	0.00e+00	777.00
IUUC-Lch-049991	Latimeria chalumnae	72.20	0.00e+00	769.00
IUUC-Loc-052309	Lepisosteus oculatus	77.52	0.00e+00	851.00
IUUC-Laf-053568	Loxodonta africana	71.60	0.00e+00	775.00
IUUC-Mcc-054849	Macaca mulatta	70.96	0.00e+00	771.00
IUUC-Mga-059971	Meleagris gallopavo	62.55	0.00e+00	663.00
IUUC-Mmr-061519	Microcebus murinus	71.35	0.00e+00	776.00
IUUC-Mdo-062090	Monodelphis domestica	68.30	0.00e+00	749.00
IUUC-Mmu-063760	Mus musculus	71.35	0.00e+00	773.00
IUUC-Mpu-065677	Mustela putorius furo	71.54	0.00e+00	775.00
IUUC-Mlu-067386	Myotis lucifugus	70.96	0.00e+00	772.00
IUUC-Nle-069742	Nomascus leucogenys	71.35	0.00e+00	776.00
IUUC-Opr-070705	Ochotona princeps	63.85	0.00e+00	696.00
IUUC-Ont-071537	Oreochromis niloticus	82.19	0.00e+00	900.00
IUUC-Oan-073193	Ornithorhynchus anatinus	71.57	0.00e+00	780.00
IUUC-Ocu-074501	Oryctolagus cuniculus	71.73	0.00e+00	775.00
IUUC-Ola-086726	Oryzias latipes	80.31	0.00e+00	878.00
IUUC-Oga-088069	Otolemur garnettii	71.26	0.00e+00	772.00
IUUC-Oar-090091	Ovis aries	70.93	0.00e+00	776.00
IUUC-Ptr-091409	Pan troglodytes	71.35	0.00e+00	776.00
IUUC-Pan-092268	Papio anubis	70.93	0.00e+00	775.00
IUUC-Psi-093685	Pelodiscus sinensis	70.27	0.00e+00	768.00
IUUC-Pma-094100	Petromyzon marinus	65.92	0.00e+00	659.00
IUUC-Pfo-096217	Poecilia formosa	80.82	0.00e+00	883.00
IUUC-Pab-098601	Pongo abelii	71.35	0.00e+00	775.00
IUUC-Pva-103021	Pteropus vampyrus	65.30	0.00e+00	701.00
IUUC-Rno-105557	Rattus norvegicus	70.76	0.00e+00	771.00
IUUC-Sha-106643	Sarcophilus harrisii	70.29	0.00e+00	763.00
IUUC-Ssc-116317	Sus scrofa	67.32	0.00e+00	712.00
IUUC-Tgu-116865	Taeniopygia guttata	70.35	0.00e+00	773.00
IUUC-Tru-118284	Takifugu rubripes	84.99	0.00e+00	923.00
IUUC-Tsy-119440	Tarsius syrichta	69.84	0.00e+00	756.00
IUUC-Tbe-128144	Tupaia belangeri	62.33	4.00e-172	597.00
IUUC-Ttr-128481	Tursiops truncatus	63.01	0.00e+00	649.00
IUUC-Xtr-131907	Xenopus tropicalis	62.60	0.00e+00	666.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence