iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.30e-16	58.7	213	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C vC++gge    ++ C+ C +++H  Cl ++  +  p+ + w Cp C++
   Q: 213  DYCEVCQQGGE----IILCDTCPRAYHLVCLDPE-LDRAPEGK-WSCPHCEK 258
           79*********....9******************.*******7.******86 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRPLIAKKNP KIPMSKMMTI LGAKWREFSA NNPFKGSAAA VAAAAAAAAA AVAEQVSAAV 60
SSATPIAPSG PPPALPPPPA PEIQPPPIRR AKTKEGKGPG HKRRGKSARA PDGRKKLRGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATGATATC CGGCTGCTGC CTTCAGCATT GGGTGTGAAG AAGCGAAAAC GGGGTCCCAA 60
GAAGCAGAAG GAAAACAAGC CAGGCAAACC CCGGAAACGA AAGAAGCTTG TGAGTATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028722--CHD3
IPR012957--CHD_C2
IPR012958--CHD_N
IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009462--DUF1086
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF08074--CHDCT2
PF08073--CHDNT
PF00385--Chromo
PF06461--DUF1086
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N

SMART

SM00298--CHROMO
SM00487--DEXDc
SM01146--DUF1086
SM01147--DUF1087
SM00490--HELICc
SM00249--PHD

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0003677--F:DNA binding
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
GO:0051297--P:centrosome organization
GO:0006333--P:chromatin assembly or disassembly
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007051--P:spindle organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004560	Anolis carolinensis	82.20	0.00e+00	2616.00
IUUC-Bta-012868	Bos taurus	95.92	0.00e+00	3059.00
IUUC-Cja-019018	Callithrix jacchus	88.37	0.00e+00	2925.00
IUUC-Cfa-021055	Canis familiaris	96.40	0.00e+00	3058.00
IUUC-Cpo-021523	Cavia porcellus	95.86	0.00e+00	3082.00
IUUC-Csa-024136	Chlorocebus sabaeus	95.81	0.00e+00	3004.00
IUUC-Dor-030167	Dipodomys ordii	94.72	0.00e+00	2428.00
IUUC-Ete-032757	Echinops telfairi	91.03	0.00e+00	2727.00
IUUC-Eeu-034777	Erinaceus europaeus	87.44	0.00e+00	2456.00
IUUC-Fca-036043	Felis catus	95.48	0.00e+00	3059.00
IUUC-Gmo-038957	Gadus morhua	79.59	0.00e+00	1453.00
IUUC-Gac-041375	Gasterosteus aculeatus	70.34	0.00e+00	2467.00
IUUC-Gma-043999	Glycine max	43.36	0.00e+00	737.00
IUUC-Ggo-045538	Gorilla gorilla	96.24	0.00e+00	2996.00
IUUC-Hsa-045916	Homo sapiens	96.35	0.00e+00	2986.00
IUUC-Itr-048463	Ictidomys tridecemlineatus	96.04	0.00e+00	2960.00
IUUC-Lch-050343	Latimeria chalumnae	79.55	0.00e+00	2024.00
IUUC-Laf-053870	Loxodonta africana	96.86	0.00e+00	2835.00
IUUC-Mcc-055499	Macaca mulatta	89.38	0.00e+00	2878.00
IUUC-Meu-056292	Macropus eugenii	87.35	0.00e+00	1133.00
IUUC-Mmr-061223	Microcebus murinus	94.83	0.00e+00	3021.00
IUUC-Mdo-062971	Monodelphis domestica	91.02	0.00e+00	2821.00
IUUC-Mmu-063920	Mus musculus	98.53	0.00e+00	3058.00
IUUC-Mpu-065809	Mustela putorius furo	96.52	0.00e+00	2922.00
IUUC-Mlu-067355	Myotis lucifugus	95.59	0.00e+00	3035.00
IUUC-Nle-069842	Nomascus leucogenys	95.37	0.00e+00	2875.00
IUUC-Opr-070960	Ochotona princeps	94.12	0.00e+00	2955.00
IUUC-Ont-072235	Oreochromis niloticus	77.22	0.00e+00	2019.00
IUUC-Oan-072885	Ornithorhynchus anatinus	60.79	0.00e+00	1881.00
IUUC-Ocu-074438	Oryctolagus cuniculus	90.13	0.00e+00	2878.00
IUUC-Oga-088374	Otolemur garnettii	95.86	0.00e+00	3036.00
IUUC-Oar-089784	Ovis aries	93.20	0.00e+00	3002.00
IUUC-Ptr-090799	Pan troglodytes	96.41	0.00e+00	2999.00
IUUC-Pfo-096265	Poecilia formosa	78.12	0.00e+00	2009.00
IUUC-Pab-098174	Pongo abelii	93.41	0.00e+00	2835.00
IUUC-Pca-100829	Procavia capensis	95.38	0.00e+00	2345.00
IUUC-Sha-107233	Sarcophilus harrisii	91.45	0.00e+00	2851.00
IUUC-Sly-110976	Solanum lycopersicum	43.76	0.00e+00	738.00
IUUC-Ssc-115751	Sus scrofa	96.08	0.00e+00	3025.00
IUUC-Tru-118648	Takifugu rubripes	78.45	0.00e+00	1995.00
IUUC-Tni-120039	Tetraodon nigroviridis	76.14	0.00e+00	2011.00
IUUC-Tbe-128117	Tupaia belangeri	90.48	0.00e+00	1304.00
IUUC-Vpa-130209	Vicugna pacos	98.14	1.00e-179	624.00
IUUC-Vvi-130849	Vitis vinifera	43.86	0.00e+00	738.00
IUUC-Xtr-132833	Xenopus tropicalis	72.47	0.00e+00	2350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence