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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046375
Ensembl Protein ID ENSP00000273183.3
UniProt Accession Q99469; B2R8S8; STAC_HUMAN
Genbank Protein ID BAA13152.1; BAG36275.1; EAW64474.1
Protein Name SH3 and cysteine-rich domain-containing protein; Src homology 3 and cysteine-rich domain-containing protein
Genbank Nucleotide ID D86640; AK313493; CH471055
Gene Name STAC
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000144681.10 ENST00000273183.7 ENSP00000273183.3
ENSG00000144681.10 ENST00000457375.6 ENSP00000393713.2
ENSG00000144681.10 ENST00000427486.5 ENSP00000397521.1
ENSG00000144681.10 ENST00000434649.1 ENSP00000398403.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.70e-15 58.3 286 343
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++  +ly + +q++++L+++ Gd+++++  e+ +e+W+kg  + + + G+fP+nFv++l+
   Q: 286  QMNTYVALYKFVPQENEDLEMRPGDIITLL--EDSNEDWWKG--KIQDRIGFFPANFVQRLQ 343
           678999************************..999*******..8***************97 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MIPPSSPRED GVDGLPKEAV GAEQPPSPAS TSSQESKLQK LKRSLSFKTK SLRSKSADNF 60
FQRTNSEDMK LQAHMVAEIS PSSSPLPAPG SLTSTPARAG LHPGGKAHAF QEYIFKKPTF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046375|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGAAGCCCGC TCGCCCGCTG CCGAGTGGCA GTCACGACTG TGAGGTCGCC GGCGAGGTGG 60
CCGCGGGCGC GGCGGGGCGG GGCAGGGCGC ACTCTCCTCC ACGCCCGCGG AAGTGCCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046375|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR002219--PE/DAG-bd
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
PROSITE

PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF00018--SH3_1
PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA
SMART

SM00109--C1
SM00326--SH3
Gene Ontology

GO:0005829--C:cytosol
GO:0030315--C:T-tubule
GO:0046872--F:metal ion binding
GO:0034605--P:cellular response to heat
GO:0035556--P:intracellular signal transduction
GO:0006936--P:muscle contraction
GO:1901385--P:regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction
KEGG hsa:6769
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002138 Ailuropoda melanoleuca 87.47 0.00e+00 653.00
IUUC-Apl-003909 Anas platyrhynchos 74.19 2.00e-160 558.00
IUUC-Aca-005108 Anolis carolinensis 76.04 3.00e-85 307.00
IUUC-Ame-011702 Astyanax mexicanus 60.10 1.00e-129 456.00
IUUC-Bta-013252 Bos taurus 92.08 0.00e+00 710.00
IUUC-Cja-018981 Callithrix jacchus 96.02 0.00e+00 723.00
IUUC-Cfa-020616 Canis familiaris 89.36 0.00e+00 643.00
IUUC-Cpo-021624 Cavia porcellus 89.10 0.00e+00 628.00
IUUC-Csa-023048 Chlorocebus sabaeus 98.63 0.00e+00 697.00
IUUC-Cho-024761 Choloepus hoffmanni 80.74 0.00e+00 639.00
IUUC-Dno-028867 Dasypus novemcinctus 86.91 0.00e+00 650.00
IUUC-Ete-033109 Echinops telfairi 87.10 2.00e-175 608.00
IUUC-Eca-033427 Equus caballus 92.57 0.00e+00 673.00
IUUC-Fca-036129 Felis catus 90.68 0.00e+00 639.00
IUUC-Fal-037364 Ficedula albicollis 78.22 5.00e-155 540.00
IUUC-Gga-040761 Gallus gallus 77.09 1.00e-174 605.00
IUUC-Gac-042076 Gasterosteus aculeatus 60.59 6.00e-132 463.00
IUUC-Ggo-044836 Gorilla gorilla 100.00 4.00e-159 553.00
IUUC-Itr-048358 Ictidomys tridecemlineatus 92.11 0.00e+00 678.00
IUUC-Lch-049737 Latimeria chalumnae 75.27 1.00e-113 402.00
IUUC-Loc-051865 Lepisosteus oculatus 70.13 1.00e-151 529.00
IUUC-Laf-053927 Loxodonta africana 90.57 0.00e+00 692.00
IUUC-Mcc-054821 Macaca mulatta 97.76 0.00e+00 756.00
IUUC-Mga-059635 Meleagris gallopavo 78.34 5.00e-146 510.00
IUUC-Mmr-061072 Microcebus murinus 95.02 0.00e+00 703.00
IUUC-Mmu-063555 Mus musculus 82.92 0.00e+00 640.00
IUUC-Mpu-066475 Mustela putorius furo 91.21 1.00e-156 545.00
IUUC-Mlu-068166 Myotis lucifugus 86.34 0.00e+00 628.00
IUUC-Nle-069985 Nomascus leucogenys 98.76 0.00e+00 768.00
IUUC-Opr-070930 Ochotona princeps 71.04 1.00e-135 476.00
IUUC-Ont-072501 Oreochromis niloticus 56.85 5.00e-132 464.00
IUUC-Oan-072818 Ornithorhynchus anatinus 82.12 6.00e-133 466.00
IUUC-Ocu-074488 Oryctolagus cuniculus 91.04 6.00e-166 576.00
IUUC-Ola-087078 Oryzias latipes 56.97 1.00e-126 446.00
IUUC-Oga-088176 Otolemur garnettii 93.07 0.00e+00 668.00
IUUC-Oar-090183 Ovis aries 87.19 0.00e+00 666.00
IUUC-Ptr-091139 Pan troglodytes 99.75 0.00e+00 776.00
IUUC-Pan-092571 Papio anubis 98.01 0.00e+00 757.00
IUUC-Psi-093399 Pelodiscus sinensis 78.08 4.00e-178 617.00
IUUC-Pma-094266 Petromyzon marinus 52.25 2.00e-105 375.00
IUUC-Pfo-096207 Poecilia formosa 60.74 7.00e-111 393.00
IUUC-Pab-097825 Pongo abelii 99.00 0.00e+00 769.00
IUUC-Pva-102481 Pteropus vampyrus 88.68 8.00e-157 546.00
IUUC-Rno-105553 Rattus norvegicus 83.97 1.00e-169 588.00
IUUC-Sha-106561 Sarcophilus harrisii 70.49 1.00e-139 489.00
IUUC-Sar-113303 Sorex araneus 89.49 7.00e-163 566.00
IUUC-Ssc-116135 Sus scrofa 91.03 0.00e+00 640.00
IUUC-Tgu-116598 Taeniopygia guttata 77.83 2.00e-177 615.00
IUUC-Tsy-118889 Tarsius syrichta 95.77 0.00e+00 710.00
IUUC-Tni-120208 Tetraodon nigroviridis 58.17 8.00e-129 453.00
IUUC-Ttr-128655 Tursiops truncatus 81.89 1.00e-175 609.00
IUUC-Vpa-130814 Vicugna pacos 93.84 7.00e-81 294.00
IUUC-Xtr-132129 Xenopus tropicalis 62.12 4.00e-122 431.00
Created Date 25-Jun-2017

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