iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068222

Ensembl Protein ID

ENSMLUP00000007133.2

UniProt Accession

G1PA37; G1PA37_MYOLU

Genbank Protein ID

ENSMLUP00000007133

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02002136

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007783.2	ENSMLUT00000007810.2	ENSMLUP00000007133.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-14	52.8	164	218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 164  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGRTGWFPSNYVREIK 218
           68999*********************7..999*******..8**************997 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MNPEEQIVTW LISLGVLDSP KKTICDPEEF LKSSLKNGVV LCKLINRLRP GSVEKYCLEP 60
QTEADCINNI NDFLKGCVTL QVEVFNPDDL YSGVNFSKVL STLLAVNKAT EDQLSERPCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTACAGTTC TAAGGAATGA ATCCAGAAGA GCAAATCGTG ACATGGCTTA TATCCTTGGG 60
AGTATTAGAT TCTCCCAAGA AAACTATCTG TGATCCAGAG GAGTTCTTGA AGTCCTCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	80.65	0.00e+00	1244.00
IUUC-Apl-003960	Anas platyrhynchos	74.00	0.00e+00	1093.00
IUUC-Aca-004988	Anolis carolinensis	68.55	0.00e+00	1023.00
IUUC-Aly-005591	Arabidopsis lyrata	38.71	6.00e-09	55.10
IUUC-Ame-011546	Astyanax mexicanus	61.05	0.00e+00	915.00
IUUC-Bta-013527	Bos taurus	93.05	0.00e+00	1382.00
IUUC-Cja-018935	Callithrix jacchus	92.92	0.00e+00	1352.00
IUUC-Cfa-021269	Canis familiaris	92.02	0.00e+00	1355.00
IUUC-Cpo-021620	Cavia porcellus	86.70	0.00e+00	1266.00
IUUC-Csa-023415	Chlorocebus sabaeus	93.18	0.00e+00	1357.00
IUUC-Dre-028580	Danio rerio	61.88	0.00e+00	937.00
IUUC-Dno-029201	Dasypus novemcinctus	88.24	0.00e+00	1335.00
IUUC-Dor-030868	Dipodomys ordii	73.23	0.00e+00	988.00
IUUC-Eca-033500	Equus caballus	93.56	0.00e+00	1362.00
IUUC-Eeu-035269	Erinaceus europaeus	84.20	3.00e-169	588.00
IUUC-Fca-035683	Felis catus	92.02	0.00e+00	1341.00
IUUC-Fal-037611	Ficedula albicollis	74.13	0.00e+00	1093.00
IUUC-Gmo-038980	Gadus morhua	59.59	0.00e+00	890.00
IUUC-Gga-040940	Gallus gallus	72.81	0.00e+00	1080.00
IUUC-Gac-042203	Gasterosteus aculeatus	58.30	0.00e+00	909.00
IUUC-Ggo-044755	Gorilla gorilla	93.31	0.00e+00	1360.00
IUUC-Hsa-046210	Homo sapiens	92.79	0.00e+00	1354.00
IUUC-Lch-049517	Latimeria chalumnae	68.65	0.00e+00	1016.00
IUUC-Loc-052393	Lepisosteus oculatus	62.68	0.00e+00	982.00
IUUC-Laf-054196	Loxodonta africana	89.82	0.00e+00	1288.00
IUUC-Mcc-055716	Macaca mulatta	93.18	0.00e+00	1357.00
IUUC-Meu-056285	Macropus eugenii	74.03	0.00e+00	682.00
IUUC-Mtr-058576	Medicago truncatula	44.62	3.00e-11	62.40
IUUC-Mga-060029	Meleagris gallopavo	73.75	0.00e+00	1100.00
IUUC-Mmr-060803	Microcebus murinus	92.15	0.00e+00	1346.00
IUUC-Mdo-062654	Monodelphis domestica	78.43	0.00e+00	1185.00
IUUC-Mmu-063479	Mus musculus	89.43	0.00e+00	1286.00
IUUC-Mpu-066065	Mustela putorius furo	92.15	0.00e+00	1340.00
IUUC-Nle-069379	Nomascus leucogenys	93.31	0.00e+00	1360.00
IUUC-Opr-070687	Ochotona princeps	73.55	0.00e+00	819.00
IUUC-Ont-072240	Oreochromis niloticus	56.83	0.00e+00	874.00
IUUC-Oan-073067	Ornithorhynchus anatinus	78.64	0.00e+00	1182.00
IUUC-Ocu-074852	Oryctolagus cuniculus	92.15	0.00e+00	1337.00
IUUC-Oga-089048	Otolemur garnettii	88.65	0.00e+00	1194.00
IUUC-Oar-089339	Ovis aries	92.92	0.00e+00	1374.00
IUUC-Pan-092666	Papio anubis	90.89	0.00e+00	1307.00
IUUC-Psi-093116	Pelodiscus sinensis	74.29	0.00e+00	1126.00
IUUC-Pfo-097394	Poecilia formosa	60.46	0.00e+00	897.00
IUUC-Pab-098567	Pongo abelii	93.31	0.00e+00	1360.00
IUUC-Pca-100997	Procavia capensis	77.61	0.00e+00	1070.00
IUUC-Pva-102500	Pteropus vampyrus	91.38	0.00e+00	1306.00
IUUC-Rno-104974	Rattus norvegicus	89.43	0.00e+00	1264.00
IUUC-Sly-111123	Solanum lycopersicum	44.23	1.00e-09	57.40
IUUC-Stu-112434	Solanum tuberosum	44.23	1.00e-09	57.40
IUUC-Sar-113420	Sorex araneus	85.97	0.00e+00	1238.00
IUUC-Ssc-115679	Sus scrofa	92.93	0.00e+00	1194.00
IUUC-Tgu-117069	Taeniopygia guttata	73.62	0.00e+00	1082.00
IUUC-Tsy-119243	Tarsius syrichta	83.20	0.00e+00	905.00
IUUC-Tni-120584	Tetraodon nigroviridis	59.87	0.00e+00	900.00
IUUC-Tbe-127994	Tupaia belangeri	76.58	0.00e+00	1090.00
IUUC-Ttr-128839	Tursiops truncatus	91.76	0.00e+00	1316.00
IUUC-Vpa-130144	Vicugna pacos	84.58	0.00e+00	1173.00
IUUC-Xtr-132624	Xenopus tropicalis	69.04	0.00e+00	1038.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence