iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026344

UUCD1 version

UUC-CiS-00469

Ensembl Protein ID

ENSCSAVP00000018495.1

UniProt Accession

H2ZLM9; H2ZLM9_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000010856.1	ENSCSAVT00000018694.1	ENSCSAVP00000018494.1
ENSCSAVG00000010856.1	ENSCSAVT00000018695.1	ENSCSAVP00000018495.1
ENSCSAVG00000010856.1	ENSCSAVT00000018696.1	ENSCSAVP00000018496.1
ENSCSAVG00000010856.1	ENSCSAVT00000018698.1	ENSCSAVP00000018498.1
ENSCSAVG00000010856.1	ENSCSAVT00000018699.1	ENSCSAVP00000018499.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.30e-98	328.0	754	1555

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           tGl+NlgNtC+mNS LQc+sn+++l++++le k+  +ln++np ++kg+++k + +l +elw++++k v+p +l  +++k+a++f+
   Q: 754  TGLSNLGNTCFMNSGLQCISNTRPLTKYFLEnKHLYELNRTNPLGMKGHIAKRYCDLTQELWSGSSKTVAPLKLRWTISKYAPRFN 839
           7******************************9999*************************************************** PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssre 166
           g++q+D+qE+laflld+l+e+l++ ++kp+ e++++d   ++de     a+e++  +n+s+i+dlF+gq++s+++cl+c + s r+
   Q: 840  GFSQHDSQELLAFLLDGLHEDLNRVQTKPYVELKDSDG--RPDEevaqeAWENHLARNQSIIVDLFHGQIRSRVRCLQCSTLSIRF 923
           *********************************99983..333334555************************************* PP
   S: 167  epfldlslpvpgkeetkke................................................................... 185
           +pf+ lslp+p+++++ +                                                                    
   Q: 924  DPFTFLSLPLPMDNSMYLDvivirlneeipvryglrlnmddtfaevrkhladkckismdavlltevlgatiktflqdnlkvrsvsv 1009
           **************87666******************************************************************* PP
   S: 186  ...................................................................................... 185
                                                                                                 
   Q: 1010 gniyafeipapvkaivcvtpngnthagsngnspdiqrgekvngtdfaqtikrvgslvhettkqsitnpaalhienknasymqtqca 1095
           ************************************************************************************** PP
   S: 186  ...................................................................................... 185
                                                                                                 
   Q: 1096 gyvvayhrkifhidvyflssqkhrpslfglplvvpcvpgrpkkelysavwrlvsrlcqprcrtagspqgreptrkdcddsmgskyp 1181
           ************************************************************************************** PP
   S: 186  ................................................................................slqdcL 191
                                                                                           +l++cL
   Q: 1182 ftlrcidaygmscgnkcpwfrfctgcviectdepwhqtsghiaidwdptalhlryqpsaerevtddssveeghrgvqqhiDLKQCL 1267
           ************************************************************************************** PP
   S: 192  esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke.. 274
           ++ft+eeel +++ y+c kck  q a+kkl++++lP++Li+hLkRf+f +   + +k +k v+fp++ +d s+f+t+++e++ +  
   Q: 1268 RAFTTEEELGKDELYHCGKCKTMQLAKKKLDIWRLPPTLIIHLKRFQFVNG--RWIKSHKVVDFPKTdFDPSSFMTKRDEENLDve 1351
           **********************************************99775..5569********************555555566 PP
   S: 275  ...................................................................................... 274
                                                                                                 
   Q: 1352 aqeittsvdadpvatnmttpqrtnnakptkpkphitfeknppngtsdpvhngnspshegvknagltarkrkasfreespplydlya 1437
           67777777777777777777777777778888888888888888888888888888899999999999999999999999999999 PP
   S: 275  ...........................................................kkkYeLiavvvHsGslssGHYvayvkn 301
                                                                      +  Y   +v +HsG l++GHY+ay+kn
   Q: 1438 ttsyiyfllystifkyipvnktykteimfsvhdpvkwieglgphlffestltsiislclCIPY---SVKCHSGILGGGHYIAYAKN 1520
           9999999999999999999999999**************************999997776666...9******************* PP
   S: 302  ekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           + ++ W++++Ds+++ev+ ++++    +taY lfY+r+
   Q: 1521 KVNNkWYCYNDSSCKEVSADNINV---DTAYTLFYERQ 1555
           75555*******************...*********96 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MGAKESRASI LSYDEASKRV TSVELQRIQE AYKRSCGFAG VMREAVFIRD VLGENVPQKL 60
SQRIFVVMSS NNRGMTFRDL LVTLVLLTRG RQEERLKLTY AVYSDERGSS VTSTSMSDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTTGTGAA AATATCGCTT ATGTGTAAAA TGTTAAATTG AAAAGTGTCA ATTGTATTGA 60
TTCCTCACCA AGTTGGAAAA CTATTTTAAA ATCAATTCTT TATTAACTGA TGATAATTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	47.37	0.00e+00	964.00
IUUC-Apl-003272	Anas platyrhynchos	46.50	0.00e+00	1138.00
IUUC-Aca-005057	Anolis carolinensis	46.95	0.00e+00	1144.00
IUUC-Ame-010781	Astyanax mexicanus	47.23	0.00e+00	1193.00
IUUC-Bta-013502	Bos taurus	45.58	0.00e+00	1051.00
IUUC-Bol-016335	Brassica oleracea	31.55	2.00e-64	239.00
IUUC-Cel-018710	Caenorhabditis elegans	30.74	1.00e-66	246.00
IUUC-Cja-018754	Callithrix jacchus	47.35	0.00e+00	1178.00
IUUC-Cfa-020526	Canis familiaris	47.14	0.00e+00	1157.00
IUUC-Cpo-021568	Cavia porcellus	45.71	0.00e+00	1048.00
IUUC-Csa-023143	Chlorocebus sabaeus	47.28	0.00e+00	1162.00
IUUC-Cin-025583	Ciona intestinalis	68.66	0.00e+00	2175.00
IUUC-Dre-028121	Danio rerio	46.83	0.00e+00	1168.00
IUUC-Dno-029911	Dasypus novemcinctus	46.68	0.00e+00	1130.00
IUUC-Dme-032094	Drosophila melanogaster	41.43	7.00e-103	367.00
IUUC-Ete-032639	Echinops telfairi	54.67	0.00e+00	687.00
IUUC-Eca-034253	Equus caballus	47.53	0.00e+00	1147.00
IUUC-Eeu-035084	Erinaceus europaeus	59.93	2.00e-101	362.00
IUUC-Fca-035474	Felis catus	45.66	0.00e+00	877.00
IUUC-Fal-036985	Ficedula albicollis	46.84	0.00e+00	1169.00
IUUC-Gmo-039568	Gadus morhua	46.98	0.00e+00	1156.00
IUUC-Gga-040509	Gallus gallus	47.02	0.00e+00	1214.00
IUUC-Gac-041757	Gasterosteus aculeatus	47.03	0.00e+00	1181.00
IUUC-Ggo-045453	Gorilla gorilla	44.91	3.00e-132	464.00
IUUC-Hsa-046107	Homo sapiens	47.70	0.00e+00	1176.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	47.67	3.00e-94	337.00
IUUC-Lch-050681	Latimeria chalumnae	42.44	0.00e+00	1002.00
IUUC-Loc-052474	Lepisosteus oculatus	45.45	0.00e+00	1175.00
IUUC-Laf-054273	Loxodonta africana	49.53	0.00e+00	764.00
IUUC-Mcc-054718	Macaca mulatta	47.35	0.00e+00	1179.00
IUUC-Meu-056558	Macropus eugenii	38.53	2.00e-119	422.00
IUUC-Mga-059892	Meleagris gallopavo	47.41	0.00e+00	1142.00
IUUC-Mmr-060866	Microcebus murinus	47.49	0.00e+00	1184.00
IUUC-Mdo-062607	Monodelphis domestica	47.69	0.00e+00	1195.00
IUUC-Mmu-063797	Mus musculus	47.68	0.00e+00	1190.00
IUUC-Mpu-066121	Mustela putorius furo	47.54	0.00e+00	1184.00
IUUC-Mlu-067581	Myotis lucifugus	46.67	0.00e+00	1159.00
IUUC-Nle-069916	Nomascus leucogenys	46.64	0.00e+00	1141.00
IUUC-Opr-071073	Ochotona princeps	34.10	4.00e-104	371.00
IUUC-Ont-071310	Oreochromis niloticus	47.06	0.00e+00	1172.00
IUUC-Oan-073356	Ornithorhynchus anatinus	47.00	0.00e+00	1166.00
IUUC-Ocu-074216	Oryctolagus cuniculus	47.79	0.00e+00	1179.00
IUUC-Ola-087434	Oryzias latipes	44.97	0.00e+00	840.00
IUUC-Oga-089034	Otolemur garnettii	46.91	0.00e+00	1120.00
IUUC-Oar-090369	Ovis aries	47.17	0.00e+00	1146.00
IUUC-Ptr-090605	Pan troglodytes	47.43	0.00e+00	1179.00
IUUC-Pan-092381	Papio anubis	46.60	0.00e+00	1120.00
IUUC-Psi-093819	Pelodiscus sinensis	46.78	0.00e+00	1150.00
IUUC-Pma-094480	Petromyzon marinus	46.48	0.00e+00	666.00
IUUC-Pfo-096561	Poecilia formosa	46.56	0.00e+00	1144.00
IUUC-Pab-097643	Pongo abelii	45.90	0.00e+00	1110.00
IUUC-Pca-100944	Procavia capensis	45.88	3.00e-127	448.00
IUUC-Pva-102732	Pteropus vampyrus	43.42	0.00e+00	1035.00
IUUC-Rno-105113	Rattus norvegicus	47.09	0.00e+00	1162.00
IUUC-Sar-113201	Sorex araneus	48.43	1.00e-157	549.00
IUUC-Tgu-117322	Taeniopygia guttata	46.92	0.00e+00	1214.00
IUUC-Tru-118705	Takifugu rubripes	65.20	6.00e-112	396.00
IUUC-Tsy-119433	Tarsius syrichta	46.12	3.00e-135	475.00
IUUC-Tni-120631	Tetraodon nigroviridis	46.68	0.00e+00	1131.00
IUUC-Tbe-127553	Tupaia belangeri	68.50	1.00e-114	406.00
IUUC-Ttr-128260	Tursiops truncatus	46.20	0.00e+00	1127.00
IUUC-Vpa-130479	Vicugna pacos	45.50	0.00e+00	1016.00
IUUC-Xtr-132686	Xenopus tropicalis	45.27	0.00e+00	1136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence