iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020670

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013229

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004969.3	ENSCAFT00000007985.3	ENSCAFP00000007394.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.90e-19	67.8	80	147
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.60e-07	28.9	179	205

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 80   CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 147
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 179  PSNCLGIRAFADAQGCIELMKVAHSYT 205
           89***********************95 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDFPGPHDKG LVLPELQVEP ANSSQATGEG CGHRLTATSH SLTPQSDMDS SSSEEFYQAV 60
HHAEQTFRKM ESYLKQQQLC DVILIVGNRK IPAHRLVLSS VSDYFAAMFT SDVCEAKQEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNC ACATCCTGCG CCTCCGCTGG AAACTCTTCA GCCATCCGTC 60
GCCGGCCCCC GGCGGCCCTG CGGGGGGCGG CTGCCTGCAA CAGGACGGCA GCGGCAGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001478	Ailuropoda melanoleuca	99.51	0.00e+00	1214.00
IUUC-Apl-003408	Anas platyrhynchos	96.23	0.00e+00	1111.00
IUUC-Aca-004384	Anolis carolinensis	89.87	0.00e+00	1117.00
IUUC-Bta-012684	Bos taurus	98.80	0.00e+00	1137.00
IUUC-Cja-019103	Callithrix jacchus	98.21	0.00e+00	1201.00
IUUC-Cpo-021951	Cavia porcellus	98.63	0.00e+00	1139.00
IUUC-Csa-023607	Chlorocebus sabaeus	98.28	0.00e+00	1134.00
IUUC-Cho-024648	Choloepus hoffmanni	87.77	0.00e+00	1006.00
IUUC-Dno-029854	Dasypus novemcinctus	97.89	0.00e+00	1197.00
IUUC-Dor-030497	Dipodomys ordii	77.51	0.00e+00	889.00
IUUC-Eca-033525	Equus caballus	98.54	0.00e+00	1199.00
IUUC-Fca-035490	Felis catus	99.49	0.00e+00	1139.00
IUUC-Fal-037099	Ficedula albicollis	97.50	0.00e+00	1105.00
IUUC-Gga-041081	Gallus gallus	96.28	0.00e+00	1129.00
IUUC-Gma-043533	Glycine max	32.51	7.00e-39	155.00
IUUC-Ggo-044717	Gorilla gorilla	98.05	0.00e+00	1199.00
IUUC-Hsa-045726	Homo sapiens	98.05	0.00e+00	1199.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	98.38	0.00e+00	1205.00
IUUC-Loc-052321	Lepisosteus oculatus	86.10	0.00e+00	1011.00
IUUC-Laf-054378	Loxodonta africana	97.40	0.00e+00	1180.00
IUUC-Mcc-054985	Macaca mulatta	98.05	0.00e+00	1199.00
IUUC-Mmr-061255	Microcebus murinus	98.85	0.00e+00	1040.00
IUUC-Mdo-062369	Monodelphis domestica	96.43	0.00e+00	1176.00
IUUC-Mmu-063334	Mus musculus	97.24	0.00e+00	1188.00
IUUC-Nle-069856	Nomascus leucogenys	98.05	0.00e+00	1199.00
IUUC-Ocu-074469	Oryctolagus cuniculus	97.73	0.00e+00	1195.00
IUUC-Obr-076712	Oryza brachyantha	28.92	8.00e-33	135.00
IUUC-Oin-080100	Oryza indica	29.27	1.00e-33	138.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.36	9.00e-33	133.00
IUUC-Oga-088528	Otolemur garnettii	97.41	0.00e+00	1191.00
IUUC-Oar-089603	Ovis aries	98.63	0.00e+00	1132.00
IUUC-Ptr-090657	Pan troglodytes	97.56	0.00e+00	1195.00
IUUC-Psi-092962	Pelodiscus sinensis	96.23	0.00e+00	1114.00
IUUC-Pab-097812	Pongo abelii	97.40	0.00e+00	1169.00
IUUC-Pva-103042	Pteropus vampyrus	98.38	0.00e+00	1202.00
IUUC-Sbi-114612	Sorghum bicolor	29.24	5.00e-35	142.00
IUUC-Ssc-115880	Sus scrofa	98.97	0.00e+00	1138.00
IUUC-Tgu-116624	Taeniopygia guttata	94.59	0.00e+00	979.00
IUUC-Tsy-119339	Tarsius syrichta	88.96	0.00e+00	1053.00
IUUC-Tbe-127398	Tupaia belangeri	99.69	0.00e+00	679.00
IUUC-Ttr-129024	Tursiops truncatus	98.38	0.00e+00	1205.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence