iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097619

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01025896

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000010127.2	ENSPPYT00000011767.2	ENSPPYP00000011326.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-17	63.5	293	322

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.fsd.tllvsGsdDgtikvWD 29
           H ++v++l+ + d tl++ G++D  + +W 
   Q: 293  HDGGVFGLCaLRDgTLVSGGGRDRRVVLWG 322
           999****97367746655588********6 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSSFGAGKTK EVIFSVEDGS VKMFLRGRPV PMMIPDELAP TYSLDTRSEL PSCRLKLDWV 60
YGYRGRDCRA NLYLLPTGEI VYFVASVAVL YSVEEQRQRH YLGHNDDIKC LAIHPDMVTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTAGCT TTGGAGCTGG GTGAGACCCT TTCGCAGACC ACCCTCCATC TCCTCTCCGC 60
GCTCCCGGGG CTTAGATCTC AGGTTTCCCC CATCCCCTGG GACCCAGGCC GGCGTGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR000595--cNMP-bd_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50042--CNMP_BINDING_3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0072686--C:mitotic spindle
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	95.38	0.00e+00	1276.00
IUUC-Aca-005316	Anolis carolinensis	81.46	0.00e+00	1068.00
IUUC-Bta-013267	Bos taurus	95.51	0.00e+00	1270.00
IUUC-Cja-019146	Callithrix jacchus	92.16	0.00e+00	1238.00
IUUC-Cfa-020267	Canis familiaris	96.90	0.00e+00	1288.00
IUUC-Dno-028961	Dasypus novemcinctus	93.06	0.00e+00	1220.00
IUUC-Eca-033785	Equus caballus	95.49	0.00e+00	1269.00
IUUC-Eeu-035302	Erinaceus europaeus	95.65	0.00e+00	724.00
IUUC-Fca-036170	Felis catus	95.52	0.00e+00	1269.00
IUUC-Ggo-044669	Gorilla gorilla	97.23	0.00e+00	1293.00
IUUC-Hsa-046141	Homo sapiens	99.07	0.00e+00	1320.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	95.05	0.00e+00	1260.00
IUUC-Laf-054137	Loxodonta africana	90.67	0.00e+00	1191.00
IUUC-Mcc-055780	Macaca mulatta	98.36	0.00e+00	1225.00
IUUC-Meu-056664	Macropus eugenii	84.28	0.00e+00	1137.00
IUUC-Mmr-060853	Microcebus murinus	95.52	0.00e+00	1283.00
IUUC-Mdo-062224	Monodelphis domestica	88.55	0.00e+00	1049.00
IUUC-Mmu-063860	Mus musculus	94.74	0.00e+00	1273.00
IUUC-Mpu-066043	Mustela putorius furo	97.04	0.00e+00	1285.00
IUUC-Mlu-067125	Myotis lucifugus	72.55	0.00e+00	892.00
IUUC-Nle-069618	Nomascus leucogenys	87.69	0.00e+00	1134.00
IUUC-Opr-070228	Ochotona princeps	86.44	0.00e+00	1139.00
IUUC-Ocu-074087	Oryctolagus cuniculus	82.85	0.00e+00	859.00
IUUC-Oga-088048	Otolemur garnettii	92.71	0.00e+00	1225.00
IUUC-Oar-089907	Ovis aries	96.01	0.00e+00	1245.00
IUUC-Pan-092082	Papio anubis	98.00	0.00e+00	1303.00
IUUC-Pca-101070	Procavia capensis	84.90	0.00e+00	1107.00
IUUC-Pva-102957	Pteropus vampyrus	91.67	0.00e+00	1214.00
IUUC-Rno-105074	Rattus norvegicus	94.14	0.00e+00	1248.00
IUUC-Sha-106692	Sarcophilus harrisii	88.61	0.00e+00	1196.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence