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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105350
UUCD1 version UUC-RaN-00343
Ensembl Protein ID ENSRNOP00000075207.1
UniProt Accession A0A0G2KA06; A0A0G2KA06_RAT
Genbank Protein ID ENSRNOP00000075207
Protein Name Kelch-like protein 22
Genbank Nucleotide ID AABR07034754
Gene Name Klhl22
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000001878.7 ENSRNOT00000068711.2 ENSRNOP00000063573.1
ENSRNOG00000001878.7 ENSRNOT00000091675.1 ENSRNOP00000075207.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACRAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 3.10e-19 69.5 137 201
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 6.60e-07 28.7 236 265
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 137  DVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 201
           9***********************************8.*************************986 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+A+l+d+ +L ++ +++ilk+F
   Q: 236  ENILDVYRLAELFDLNRLTQQLDTYILKNF 265
           8***************************** PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MGAGIATGGR AGLAAAPGVT SGSSAAAAVV ERSRRARAVS AKSPGCTSLD PVQAERTDLS 60
GRNGATFYPR QLPRLTTVVR AAAAVRMAEE QDFAQLCKLS TQPSHSHCVN NTYRSTQHSQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105350|E3,BTB_3-box|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGAGAGCGGC CACAGCTTGC GGCAGCACCA GGTCAGCTGC GAGGCATGAA CCGTGTGGGC 60
CTGGCAGGCC TTCGTCGCCG AGCTTGCGCT GCACGCGGGG ATGGGAGAGG GAGCGGGGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105350|E3,BTB_3-box|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002097 Ailuropoda melanoleuca 94.32 0.00e+00 1175.00
IUUC-Apl-004081 Anas platyrhynchos 78.04 0.00e+00 985.00
IUUC-Aca-005015 Anolis carolinensis 67.34 0.00e+00 836.00
IUUC-Ame-011712 Astyanax mexicanus 58.69 0.00e+00 721.00
IUUC-Bta-012594 Bos taurus 91.56 0.00e+00 1165.00
IUUC-Cja-019752 Callithrix jacchus 94.27 0.00e+00 978.00
IUUC-Cfa-020884 Canis familiaris 94.48 0.00e+00 1206.00
IUUC-Cpo-021711 Cavia porcellus 93.99 0.00e+00 1203.00
IUUC-Csa-023211 Chlorocebus sabaeus 94.81 0.00e+00 1206.00
IUUC-Dre-028395 Danio rerio 60.00 0.00e+00 749.00
IUUC-Dno-030096 Dasypus novemcinctus 91.29 0.00e+00 1164.00
IUUC-Dor-030709 Dipodomys ordii 95.11 0.00e+00 702.00
IUUC-Eca-033388 Equus caballus 94.81 0.00e+00 1209.00
IUUC-Eeu-034616 Erinaceus europaeus 82.31 0.00e+00 1032.00
IUUC-Fca-035815 Felis catus 94.32 0.00e+00 1204.00
IUUC-Fal-037311 Ficedula albicollis 78.80 0.00e+00 972.00
IUUC-Gmo-039571 Gadus morhua 53.44 3.00e-156 545.00
IUUC-Gga-040992 Gallus gallus 77.87 0.00e+00 986.00
IUUC-Gac-042041 Gasterosteus aculeatus 57.65 0.00e+00 682.00
IUUC-Ggo-045141 Gorilla gorilla 88.96 0.00e+00 1130.00
IUUC-Hsa-045984 Homo sapiens 94.97 0.00e+00 1208.00
IUUC-Itr-048890 Ictidomys tridecemlineatus 95.13 0.00e+00 1216.00
IUUC-Lch-049700 Latimeria chalumnae 62.90 0.00e+00 724.00
IUUC-Loc-052141 Lepisosteus oculatus 63.65 0.00e+00 792.00
IUUC-Laf-053487 Loxodonta africana 92.18 0.00e+00 1165.00
IUUC-Mcc-054682 Macaca mulatta 94.92 0.00e+00 999.00
IUUC-Meu-055937 Macropus eugenii 72.26 0.00e+00 924.00
IUUC-Mga-059953 Meleagris gallopavo 77.87 0.00e+00 986.00
IUUC-Mmr-061743 Microcebus murinus 94.48 0.00e+00 1202.00
IUUC-Mdo-062328 Monodelphis domestica 80.97 0.00e+00 1045.00
IUUC-Mmu-063979 Mus musculus 98.06 0.00e+00 1273.00
IUUC-Mpu-066750 Mustela putorius furo 94.64 0.00e+00 1206.00
IUUC-Mlu-066960 Myotis lucifugus 92.37 0.00e+00 1174.00
IUUC-Nle-069690 Nomascus leucogenys 95.38 0.00e+00 1090.00
IUUC-Opr-071059 Ochotona princeps 87.84 0.00e+00 1092.00
IUUC-Ont-072004 Oreochromis niloticus 58.14 0.00e+00 687.00
IUUC-Oan-073172 Ornithorhynchus anatinus 63.92 0.00e+00 722.00
IUUC-Ocu-074310 Oryctolagus cuniculus 91.94 2.00e-140 490.00
IUUC-Ola-086599 Oryzias latipes 57.22 0.00e+00 694.00
IUUC-Oga-087980 Otolemur garnettii 94.32 0.00e+00 1199.00
IUUC-Oar-089956 Ovis aries 77.25 0.00e+00 892.00
IUUC-Ptr-090598 Pan troglodytes 95.58 0.00e+00 1096.00
IUUC-Pan-092387 Papio anubis 94.73 0.00e+00 999.00
IUUC-Psi-093484 Pelodiscus sinensis 78.48 0.00e+00 1007.00
IUUC-Pma-094224 Petromyzon marinus 50.34 9.00e-171 593.00
IUUC-Pfo-096149 Poecilia formosa 58.92 0.00e+00 714.00
IUUC-Pab-098097 Pongo abelii 94.81 0.00e+00 1209.00
IUUC-Pca-100118 Procavia capensis 93.75 0.00e+00 694.00
IUUC-Pva-103174 Pteropus vampyrus 91.09 4.00e-140 491.00
IUUC-Sha-106817 Sarcophilus harrisii 80.08 9.00e-123 434.00
IUUC-Sar-113490 Sorex araneus 95.34 0.00e+00 650.00
IUUC-Ssc-115827 Sus scrofa 93.83 0.00e+00 1195.00
IUUC-Tgu-116748 Taeniopygia guttata 81.75 0.00e+00 901.00
IUUC-Tru-118644 Takifugu rubripes 57.84 0.00e+00 694.00
IUUC-Tsy-118888 Tarsius syrichta 88.01 0.00e+00 986.00
IUUC-Tni-120060 Tetraodon nigroviridis 54.10 7.00e-175 607.00
IUUC-Ttr-129183 Tursiops truncatus 93.17 0.00e+00 1068.00
IUUC-Xtr-132780 Xenopus tropicalis 71.03 0.00e+00 879.00
Created Date 25-Jun-2017

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