iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004411

Ensembl Protein ID

ENSACAP00000005438.2

UniProt Accession

G1KE94; G1KE94_ANOCA

Protein Name

Autophagy protein 5

Gene Name

atg5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005534.3	ENSACAT00000005556.3	ENSACAP00000005438.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	22.90	6.00e-09	56.20	IUUC-Sce-106216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Functional Description
(View)

Involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RISYLTLVTD KVRKHFQKVM 60
KQEDIGEIWF ENEGTPLKWH HPIGLLFDLH ASNTALPWNI TVHFKNFPEK DLLHCPSKDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGATGGTGTG GTTACTTGAA CCACGCACGC GGGTGAGAAA GGCTTGCCCT CTGCTGCCCC 60
CTGAAGGAGA GGCCGCGCAA CAACAAGCGG CGCCTTCAGC CCGCACTTCG TGGTGACGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0000045--P:autophagosome assembly
GO:0001974--P:blood vessel remodeling
GO:0006501--P:C-terminal protein lipidation
GO:0019725--P:cellular homeostasis
GO:0006995--P:cellular response to nitrogen starvation
GO:0071500--P:cellular response to nitrosative stress
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0044804--P:nucleophagy
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000583	Aegilops tauschii	30.99	1.00e-21	98.20
IUUC-Aml-002403	Ailuropoda melanoleuca	90.29	5.00e-149	519.00
IUUC-Atr-002645	Amborella trichopoda	25.52	2.00e-20	92.80
IUUC-Apl-003611	Anas platyrhynchos	91.37	5.00e-152	529.00
IUUC-Aly-005636	Arabidopsis lyrata	26.59	3.00e-24	105.00
IUUC-Ath-006959	Arabidopsis thaliana	27.19	8.00e-24	103.00
IUUC-Ago-007978	Ashbya gossypii	25.10	9.00e-08	50.40
IUUC-Acl-008328	Aspergillus clavatus	25.30	1.00e-17	83.20
IUUC-Afl-008638	Aspergillus flavus	26.65	6.00e-26	110.00
IUUC-Afu-009042	Aspergillus fumigatus	27.73	7.00e-27	114.00
IUUC-Ani-009364	Aspergillus nidulans	28.38	2.00e-22	99.40
IUUC-Aor-009889	Aspergillus oryzae	26.65	7.00e-26	110.00
IUUC-Ate-010511	Aspergillus terreus	34.41	6.00e-10	55.50
IUUC-Ame-011644	Astyanax mexicanus	84.81	1.00e-37	146.00
IUUC-Bgr-012153	Blumeria graminis	27.94	5.00e-15	74.30
IUUC-Bta-012360	Bos taurus	92.45	4.00e-84	303.00
IUUC-Bci-013723	Botrytis cinerea	25.43	9.00e-15	73.60
IUUC-Bdi-014520	Brachypodium distachyon	31.58	1.00e-18	87.40
IUUC-Bol-016053	Brassica oleracea	26.11	2.00e-24	106.00
IUUC-Bra-017072	Brassica rapa	26.49	7.00e-25	107.00
IUUC-Cel-018529	Caenorhabditis elegans	34.06	3.00e-36	145.00
IUUC-Cja-019569	Callithrix jacchus	89.93	5.00e-147	513.00
IUUC-Cfa-020473	Canis familiaris	90.29	3.00e-147	513.00
IUUC-Cpo-021421	Cavia porcellus	88.13	1.00e-144	504.00
IUUC-Cre-022862	Chlamydomonas reinhardtii	28.74	1.00e-16	79.30
IUUC-Csa-024197	Chlorocebus sabaeus	90.29	1.00e-147	514.00
IUUC-Cho-024521	Choloepus hoffmanni	86.78	3.00e-120	423.00
IUUC-Cin-025119	Ciona intestinalis	45.11	2.00e-65	241.00
IUUC-Csv-026192	Ciona savignyi	43.17	2.00e-63	235.00
IUUC-Cgl-026686	Colletotrichum gloeosporioides	22.83	1.00e-07	50.10
IUUC-Dre-028466	Danio rerio	80.58	1.00e-134	472.00
IUUC-Dse-031228	Dothistroma septosporum	26.95	1.00e-28	119.00
IUUC-Dme-031703	Drosophila melanogaster	46.72	2.00e-72	265.00
IUUC-Ete-032482	Echinops telfairi	86.36	8.00e-121	425.00
IUUC-Eca-034036	Equus caballus	89.21	2.00e-146	511.00
IUUC-Eeu-035235	Erinaceus europaeus	90.57	9.00e-83	299.00
IUUC-Fca-036263	Felis catus	90.29	2.00e-147	514.00
IUUC-Fal-037064	Ficedula albicollis	90.29	8.00e-151	525.00
IUUC-Fox-037813	Fusarium oxysporum	24.73	1.00e-15	76.60
IUUC-Fso-038139	Fusarium solani	25.44	2.00e-17	82.40
IUUC-Gmo-039509	Gadus morhua	81.42	2.00e-111	394.00
IUUC-Ggr-040111	Gaeumannomyces graminis	25.97	9.00e-14	70.50
IUUC-Gga-040517	Gallus gallus	90.29	2.00e-150	524.00
IUUC-Gac-042270	Gasterosteus aculeatus	70.70	2.00e-113	401.00
IUUC-Gma-044400	Glycine max	34.34	4.00e-21	94.70
IUUC-Ggo-045048	Gorilla gorilla	89.57	1.00e-145	508.00
IUUC-Hsa-046744	Homo sapiens	90.29	4.00e-147	513.00
IUUC-Kpa-049174	Komagataella pastoris	24.09	1.00e-11	63.50
IUUC-Lch-049475	Latimeria chalumnae	87.77	4.00e-146	509.00
IUUC-Lpe-051283	Leersia perrieri	34.04	4.00e-21	96.70
IUUC-Loc-052446	Lepisosteus oculatus	83.45	3.00e-140	490.00
IUUC-Lma-053278	Leptosphaeria maculans	26.33	6.00e-29	120.00
IUUC-Laf-054020	Loxodonta africana	89.57	2.00e-148	517.00
IUUC-Mcc-055176	Macaca mulatta	90.29	4.00e-147	513.00
IUUC-Mor-057164	Magnaporthe oryzae	26.77	8.00e-18	84.00
IUUC-Mpo-057428	Magnaporthe poae	28.50	2.00e-14	72.80
IUUC-Mtr-058424	Medicago truncatula	33.54	9.00e-21	93.60
IUUC-Mla-058872	Melampsora laricipopulina	29.32	4.00e-31	129.00
IUUC-Mga-059859	Meleagris gallopavo	90.29	2.00e-150	524.00
IUUC-Mmr-061482	Microcebus murinus	90.65	2.00e-147	514.00
IUUC-Mdo-062371	Monodelphis domestica	89.57	3.00e-149	520.00
IUUC-Mmu-063139	Mus musculus	88.49	5.00e-147	513.00
IUUC-Mac-065332	Musa acuminata	34.29	1.00e-23	103.00
IUUC-Mpu-066783	Mustela putorius furo	89.57	3.00e-146	510.00
IUUC-Mlu-068165	Myotis lucifugus	88.85	1.00e-146	511.00
IUUC-Nfi-068578	Neosartorya fischeri	27.90	2.00e-27	115.00
IUUC-Ncr-068636	Neurospora crassa	24.81	6.00e-12	64.70
IUUC-Nle-069740	Nomascus leucogenys	89.93	4.00e-147	513.00
IUUC-Opr-070802	Ochotona princeps	91.19	1.00e-81	296.00
IUUC-Ont-072222	Oreochromis niloticus	78.14	2.00e-132	464.00
IUUC-Oan-072760	Ornithorhynchus anatinus	91.79	2.00e-108	384.00
IUUC-Ocu-074844	Oryctolagus cuniculus	88.00	4.00e-89	320.00
IUUC-Oba-075834	Oryza barthii	32.20	3.00e-22	99.00
IUUC-Obr-076230	Oryza brachyantha	31.73	2.00e-13	69.70
IUUC-Ogl-077554	Oryza glaberrima	32.20	3.00e-22	99.00
IUUC-Ogu-078687	Oryza glumaepatula	32.20	2.00e-22	99.80
IUUC-Oin-079677	Oryza indica	25.51	2.00e-23	103.00
IUUC-Olo-081078	Oryza longistaminata	34.72	1.00e-22	100.00
IUUC-Ome-081548	Oryza meridionalis	32.77	4.00e-25	109.00
IUUC-Oni-082050	Oryza nivara	32.77	6.00e-23	101.00
IUUC-Opu-083609	Oryza punctata	32.58	6.00e-23	101.00
IUUC-Oru-085057	Oryza rufipogon	32.77	1.00e-22	100.00
IUUC-Osa-085917	Oryza sativa	32.77	1.00e-22	100.00
IUUC-Ola-087032	Oryzias latipes	77.78	3.00e-131	460.00
IUUC-Oga-088468	Otolemur garnettii	89.21	3.00e-151	527.00
IUUC-Oar-089751	Ovis aries	89.57	1.00e-146	511.00
IUUC-Ptr-091064	Pan troglodytes	90.29	4.00e-147	513.00
IUUC-Pan-092505	Papio anubis	89.93	2.00e-148	518.00
IUUC-Psi-093086	Pelodiscus sinensis	91.01	1.00e-152	531.00
IUUC-Pno-094825	Phaeosphaeria nodorum	27.82	5.00e-26	111.00
IUUC-Ppa-095419	Physcomitrella patens	31.33	1.00e-22	100.00
IUUC-Pfo-096224	Poecilia formosa	76.70	2.00e-129	454.00
IUUC-Pab-098501	Pongo abelii	89.57	6.00e-146	509.00
IUUC-Pop-099243	Populus trichocarpa	25.84	1.00e-20	93.60
IUUC-Ppe-101255	Prunus persica	25.92	1.00e-23	103.00
IUUC-Pva-102828	Pteropus vampyrus	89.21	1.00e-145	508.00
IUUC-Pgr-103672	Puccinia graminis	27.36	1.00e-26	114.00
IUUC-Ptt-104013	Puccinia triticina	24.62	2.00e-22	99.80
IUUC-Pyt-104615	Pyrenophora triticirepentis	27.83	2.00e-28	119.00
IUUC-Rno-106089	Rattus norvegicus	84.68	2.00e-124	437.00
IUUC-Sce-106216	Saccharomyces cerevisiae	22.90	2.00e-09	56.20
IUUC-Sha-106484	Sarcophilus harrisii	88.85	2.00e-148	517.00
IUUC-Sja-107699	Schizosaccharomyces japonicus	28.41	3.00e-25	108.00
IUUC-Spo-108177	Schizosaccharomyces pombe	26.59	2.00e-18	85.90
IUUC-Ssl-108475	Sclerotinia sclerotiorum	25.77	1.00e-14	73.20
IUUC-Smo-109473	Selaginella moellendorffii	25.98	6.00e-21	94.40
IUUC-Sit-110736	Setaria italica	33.51	4.00e-27	115.00
IUUC-Sly-111657	Solanum lycopersicum	35.37	7.00e-25	108.00
IUUC-Sar-113050	Sorex araneus	73.97	1.00e-98	352.00
IUUC-Sbi-114258	Sorghum bicolor	32.16	2.00e-23	102.00
IUUC-Sre-114902	Sporisorium reilianum	31.19	9.00e-23	101.00
IUUC-Ssc-116166	Sus scrofa	83.81	5.00e-138	483.00
IUUC-Tgu-116814	Taeniopygia guttata	90.29	5.00e-151	526.00
IUUC-Tru-118172	Takifugu rubripes	78.49	9.00e-131	459.00
IUUC-Tsy-119010	Tarsius syrichta	77.70	2.00e-125	441.00
IUUC-Tni-120397	Tetraodon nigroviridis	81.52	1.00e-102	364.00
IUUC-Tca-121283	Theobroma cacao	26.91	1.00e-24	107.00
IUUC-Tvi-122545	Trichoderma virens	23.21	2.00e-13	68.90
IUUC-Tae-122685	Triticum aestivum	30.41	5.00e-22	97.80
IUUC-Tur-126407	Triticum urartu	32.67	2.00e-22	99.40
IUUC-Tme-126913	Tuber melanosporum	31.51	8.00e-38	150.00
IUUC-Tbe-127738	Tupaia belangeri	81.41	4.00e-94	336.00
IUUC-Ttr-128528	Tursiops truncatus	89.57	3.00e-146	510.00
IUUC-Uma-129625	Ustilago maydis	29.49	2.00e-21	96.70
IUUC-Vda-129906	Verticillium dahliae	24.80	1.00e-11	63.20
IUUC-Vpa-130223	Vicugna pacos	88.49	8.00e-141	492.00
IUUC-Vvi-131617	Vitis vinifera	31.76	3.00e-22	99.00
IUUC-Xtr-132288	Xenopus tropicalis	87.05	1.00e-144	504.00
IUUC-Xma-134214	Xiphophorus maculatus	81.03	3.00e-97	347.00
IUUC-Yli-134377	Yarrowia lipolytica	23.27	4.00e-10	58.20
IUUC-Zma-135108	Zea mays	34.03	9.00e-22	97.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence