iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042263

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 6

Genbank Nucleotide ID

EF371371

Gene Name

socs6; SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000002698.1	ENSGACT00000003542.1	ENSGACP00000003530.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.70e-16	60.2	489	536

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +    kLPLP+++kdYL++++y
   Q: 489  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---RKLPLPNKMKDYLQEKHY 536
           5788999********************888...***************997 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MKKISLKTIR KSLSIKGKEE GDFVMLQQPS VTPEFSKDES LFGGCYTKEL SGCDLGSEED 60
KGSQNKSRSK SESLMGSLKR RLSTKQKAKV KGSPSAIGSV DDDDAFSSSS VPISFNEVKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAGA TAAGCCTTAA GACCATCCGC AAGTCCCTCA GCATAAAGGG CAAGGAGGAG 60
GGTGACTTTG TCATGCTGCA GCAGCCCTCG GTGACTCCAG AATTTTCTAA GGACGAGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	70.30	0.00e+00	664.00
IUUC-Apl-004035	Anas platyrhynchos	71.59	0.00e+00	686.00
IUUC-Aca-004782	Anolis carolinensis	70.11	0.00e+00	663.00
IUUC-Ame-011790	Astyanax mexicanus	75.05	0.00e+00	676.00
IUUC-Bta-012579	Bos taurus	90.64	3.00e-99	355.00
IUUC-Cel-018643	Caenorhabditis elegans	34.11	2.00e-11	62.00
IUUC-Cja-019528	Callithrix jacchus	70.85	0.00e+00	700.00
IUUC-Cfa-020678	Canis familiaris	70.48	0.00e+00	697.00
IUUC-Cpo-021947	Cavia porcellus	71.59	0.00e+00	711.00
IUUC-Csa-023935	Chlorocebus sabaeus	71.27	0.00e+00	697.00
IUUC-Cho-024477	Choloepus hoffmanni	68.82	0.00e+00	679.00
IUUC-Cin-025413	Ciona intestinalis	67.06	1.00e-63	237.00
IUUC-Csv-026247	Ciona savignyi	66.27	2.00e-62	232.00
IUUC-Dre-027636	Danio rerio	77.80	0.00e+00	719.00
IUUC-Dno-029048	Dasypus novemcinctus	69.19	0.00e+00	685.00
IUUC-Dor-030401	Dipodomys ordii	69.93	0.00e+00	674.00
IUUC-Dme-031876	Drosophila melanogaster	45.12	2.00e-35	144.00
IUUC-Ete-033116	Echinops telfairi	44.01	1.00e-48	186.00
IUUC-Eca-033825	Equus caballus	71.03	0.00e+00	664.00
IUUC-Fca-036253	Felis catus	69.74	0.00e+00	628.00
IUUC-Fal-037614	Ficedula albicollis	71.77	0.00e+00	690.00
IUUC-Gmo-038928	Gadus morhua	83.24	0.00e+00	812.00
IUUC-Gga-040177	Gallus gallus	70.70	0.00e+00	683.00
IUUC-Ggo-045288	Gorilla gorilla	70.53	0.00e+00	694.00
IUUC-Hsa-046409	Homo sapiens	70.90	0.00e+00	698.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	70.90	0.00e+00	671.00
IUUC-Lch-050354	Latimeria chalumnae	71.64	0.00e+00	715.00
IUUC-Loc-052319	Lepisosteus oculatus	76.58	0.00e+00	773.00
IUUC-Laf-054070	Loxodonta africana	70.72	0.00e+00	697.00
IUUC-Mcc-055045	Macaca mulatta	71.09	0.00e+00	696.00
IUUC-Meu-055917	Macropus eugenii	70.85	0.00e+00	716.00
IUUC-Mga-059273	Meleagris gallopavo	72.03	0.00e+00	701.00
IUUC-Mmr-061597	Microcebus murinus	71.03	0.00e+00	696.00
IUUC-Mdo-062492	Monodelphis domestica	41.71	6.00e-57	214.00
IUUC-Mmu-063374	Mus musculus	64.89	2.00e-177	615.00
IUUC-Mpu-065967	Mustela putorius furo	69.00	0.00e+00	663.00
IUUC-Mlu-067532	Myotis lucifugus	70.30	0.00e+00	677.00
IUUC-Nle-069373	Nomascus leucogenys	70.90	0.00e+00	696.00
IUUC-Opr-070873	Ochotona princeps	69.80	0.00e+00	717.00
IUUC-Ont-072498	Oreochromis niloticus	91.60	0.00e+00	945.00
IUUC-Oan-072943	Ornithorhynchus anatinus	57.95	8.00e-70	257.00
IUUC-Ocu-073870	Oryctolagus cuniculus	70.85	0.00e+00	677.00
IUUC-Ola-086866	Oryzias latipes	96.51	2.00e-121	427.00
IUUC-Oga-089057	Otolemur garnettii	69.85	0.00e+00	672.00
IUUC-Oar-089841	Ovis aries	50.65	2.00e-126	445.00
IUUC-Ptr-091054	Pan troglodytes	70.72	0.00e+00	696.00
IUUC-Pma-094253	Petromyzon marinus	74.67	5.00e-95	341.00
IUUC-Pfo-097179	Poecilia formosa	85.63	0.00e+00	822.00
IUUC-Pab-097702	Pongo abelii	71.09	0.00e+00	700.00
IUUC-Pca-100671	Procavia capensis	58.19	2.00e-82	300.00
IUUC-Rno-106044	Rattus norvegicus	64.40	5.00e-177	613.00
IUUC-Sha-107139	Sarcophilus harrisii	68.71	0.00e+00	633.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	7.70e-02	30.80
IUUC-Sar-112975	Sorex araneus	53.15	4.00e-27	115.00
IUUC-Ssc-115343	Sus scrofa	69.00	0.00e+00	670.00
IUUC-Tgu-117061	Taeniopygia guttata	71.43	0.00e+00	691.00
IUUC-Tni-119829	Tetraodon nigroviridis	88.06	0.00e+00	858.00
IUUC-Ttr-129148	Tursiops truncatus	68.27	0.00e+00	641.00
IUUC-Vpa-130780	Vicugna pacos	67.53	0.00e+00	629.00
IUUC-Vvi-130966	Vitis vinifera	32.69	9.60e-02	30.40
IUUC-Xtr-132513	Xenopus tropicalis	69.87	0.00e+00	688.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence