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Tag Content
UUCD2 ID IUUC-Bta-013081
UUCD1 version UUC-BoT-00007
Ensembl Protein ID ENSBTAP00000006533.5
UniProt Accession A0JN86; PCGF5_BOVIN
Genbank Protein ID AAI26566.1
Protein Name Polycomb group RING finger protein 5
Genbank Nucleotide ID BC126565
Gene Name PCGF5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000004964.5 ENSBTAT00000006533.5 ENSBTAP00000006533.5
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UDP/UFD/RAWUL 2.40e-32 111.4 138 249
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/RAWUL
   S: 1    islsLeplesnkakddsk...lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwk.......... 76
           i+++L++l++n++++d++   l+kk++rcs+r+tV+++kkfl++klkl+ssye+d+lc++e++++++t+e+i y+++w+          
   Q: 138  IAICLDCLRNNGQSGDNVvkgLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFI-YMTRWRlrgenfrcln 225
           79**********************************************************************.**************** PP
   S: 77   ..............kegpLvLqYr 86
                         +++p+vLqYr
   Q: 226  csasqvcsqdgplyQSYPMVLQYR 249
           ***********************9 PP
   
Organism Bos taurus
Functional Description
(View)

Functional Description


     Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
 Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
Protein Sequence
(Fasta)
MATQRKHLVK DFNPYITCYI CKGYLIKPTT VTECLHTFCK TCIVQHFEDS NDCPRCGNQV 60
HETNPLEMLR LDNTLEEIIF KLVPGLREQL ERESEFWKKN KPQENGQDDM SKVDKPKVDE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-013081|ULD,RAWUL|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGAAGATA TGGGAAAGCA GAACCACCAA AAGGAGTGAT GACCAGCGAT CTCATGAGAA 60
GTCTGGATGT TAGTTCTCAT GCCTCGGGAT ACCCAGTTGG GAACTCCACA CCAGCTCCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-013081|ULD,RAWUL|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF16207--RAWUL
SMART

SM00184--RING
Gene Ontology

GO:0005813--C:centrosome
GO:0005730--C:nucleolus
GO:0031519--C:PcG protein complex
GO:0008270--F:zinc ion binding
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
KEGG bta:528946
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002093 Ailuropoda melanoleuca 98.07 4.00e-140 489.00
IUUC-Apl-003757 Anas platyrhynchos 94.14 5.00e-120 423.00
IUUC-Aca-005032 Anolis carolinensis 88.28 7.00e-110 389.00
IUUC-Ame-011418 Astyanax mexicanus 68.73 3.00e-93 333.00
IUUC-Cja-019296 Callithrix jacchus 97.66 1.00e-137 481.00
IUUC-Cfa-020437 Canis familiaris 98.44 3.00e-140 490.00
IUUC-Cpo-022107 Cavia porcellus 98.06 5.00e-140 489.00
IUUC-Csa-023103 Chlorocebus sabaeus 98.44 6.00e-133 466.00
IUUC-Cho-025053 Choloepus hoffmanni 100.00 8.00e-38 150.00
IUUC-Dre-028409 Danio rerio 71.88 1.00e-98 352.00
IUUC-Dno-030077 Dasypus novemcinctus 98.83 7.00e-141 492.00
IUUC-Dor-030893 Dipodomys ordii 98.17 6.00e-117 412.00
IUUC-Ete-033131 Echinops telfairi 79.69 3.00e-105 374.00
IUUC-Eca-034226 Equus caballus 95.70 4.00e-136 476.00
IUUC-Eeu-034466 Erinaceus europaeus 81.64 8.00e-109 385.00
IUUC-Fca-035545 Felis catus 99.22 9.00e-142 495.00
IUUC-Fal-037615 Ficedula albicollis 94.14 5.00e-120 423.00
IUUC-Gmo-038871 Gadus morhua 65.75 8.00e-80 289.00
IUUC-Gga-040926 Gallus gallus 92.97 1.00e-125 441.00
IUUC-Gac-042006 Gasterosteus aculeatus 76.08 3.00e-98 350.00
IUUC-Ggo-045087 Gorilla gorilla 98.44 6.00e-133 466.00
IUUC-Hsa-046738 Homo sapiens 98.44 6.00e-133 466.00
IUUC-Itr-048443 Ictidomys tridecemlineatus 98.41 6.00e-99 352.00
IUUC-Lch-050434 Latimeria chalumnae 82.81 2.00e-111 394.00
IUUC-Loc-052649 Lepisosteus oculatus 78.21 9.00e-108 382.00
IUUC-Laf-053509 Loxodonta africana 98.83 6.00e-141 492.00
IUUC-Mcc-055709 Macaca mulatta 98.44 4.00e-133 466.00
IUUC-Meu-056663 Macropus eugenii 80.86 1.00e-108 385.00
IUUC-Mga-059573 Meleagris gallopavo 92.91 3.00e-124 437.00
IUUC-Mmr-060776 Microcebus murinus 99.22 2.00e-142 498.00
IUUC-Mdo-061959 Monodelphis domestica 96.88 1.00e-137 481.00
IUUC-Mmu-063483 Mus musculus 88.28 6.00e-118 416.00
IUUC-Mpu-066861 Mustela putorius furo 99.22 9.00e-142 495.00
IUUC-Mlu-067880 Myotis lucifugus 98.83 6.00e-141 492.00
IUUC-Nle-069264 Nomascus leucogenys 98.44 6.00e-133 466.00
IUUC-Opr-070746 Ochotona princeps 71.09 2.00e-89 322.00
IUUC-Ont-071361 Oreochromis niloticus 75.19 2.00e-101 361.00
IUUC-Oan-073482 Ornithorhynchus anatinus 79.07 4.00e-109 387.00
IUUC-Ocu-073885 Oryctolagus cuniculus 98.44 1.00e-140 491.00
IUUC-Ola-086999 Oryzias latipes 76.47 9.00e-105 372.00
IUUC-Oga-088504 Otolemur garnettii 98.05 2.00e-140 491.00
IUUC-Oar-089963 Ovis aries 98.44 8.00e-141 492.00
IUUC-Ptr-090820 Pan troglodytes 97.66 3.00e-132 464.00
IUUC-Pan-092600 Papio anubis 98.44 4.00e-133 466.00
IUUC-Psi-093699 Pelodiscus sinensis 94.14 2.00e-127 447.00
IUUC-Pma-094238 Petromyzon marinus 63.81 1.00e-88 318.00
IUUC-Pfo-096402 Poecilia formosa 71.71 1.00e-93 335.00
IUUC-Pab-097621 Pongo abelii 98.44 6.00e-133 466.00
IUUC-Pca-100342 Procavia capensis 97.66 7.00e-132 462.00
IUUC-Pva-103118 Pteropus vampyrus 99.22 4.00e-134 470.00
IUUC-Rno-105427 Rattus norvegicus 94.22 1.00e-112 399.00
IUUC-Sha-107627 Sarcophilus harrisii 95.24 8.00e-95 338.00
IUUC-Sit-109956 Setaria italica 36.04 3.00e-11 63.50
IUUC-Sar-113005 Sorex araneus 85.94 7.00e-127 446.00
IUUC-Ssc-116448 Sus scrofa 82.76 5.00e-82 296.00
IUUC-Tgu-117081 Taeniopygia guttata 94.14 5.00e-120 423.00
IUUC-Tru-117696 Takifugu rubripes 71.05 1.00e-94 339.00
IUUC-Tsy-119052 Tarsius syrichta 83.49 8.00e-103 365.00
IUUC-Tni-120530 Tetraodon nigroviridis 72.31 2.00e-95 341.00
IUUC-Tbe-127914 Tupaia belangeri 79.30 7.00e-105 372.00
IUUC-Ttr-128739 Tursiops truncatus 83.98 4.00e-112 397.00
IUUC-Vpa-130189 Vicugna pacos 97.66 9.00e-138 482.00
IUUC-Xtr-131995 Xenopus tropicalis 78.99 1.00e-100 358.00
IUUC-Xma-133038 Xiphophorus maculatus 76.68 3.00e-87 314.00
Created Date 25-Jun-2017

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