iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000881.3	ENSMMUT00000001252.3	ENSMMUP00000001173.3
ENSMMUG00000000881.3	ENSMMUT00000001254.2	ENSMMUP00000001175.2
ENSMMUG00000000881.3	ENSMMUT00000001257.2	ENSMMUP00000001178.2
ENSMMUG00000000881.3	ENSMMUT00000001259.3	ENSMMUP00000001180.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.60e-06	27.3	161	200
ULD/UDP/UFD/RAWUL	2.90e-30	105.7	274	369

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 161  CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 200
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++ +          ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 274  ISLSIEFFDQNRLDRKVNkdkekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 362
           7899999999998887768888899999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 363  PLPLKYR 369
           ******9 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MELSESVQKG FQMLADPGSF DSNAFTLLLR AAFQSLLDAQ ADEAVLDHPD LKHIDPVVLK 60
HCHAAAATYI LEAGKHRADK STLSTYLEDC KFDRERIELF CTEYQNNKNS LEILLGRTLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCTCT CCGAGTCTGT GCAGAAAGGC TTCCAGATGC TGGCGGATCC CGGCTCCTTC 60
GACTCCAACG CCTTCACGCT TCTCCTCCGG GCGGCTTTCC AGAGCCTGCT GGACGCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000603	Aegilops tauschii	40.85	5.00e-12	65.90
IUUC-Aml-001498	Ailuropoda melanoleuca	98.77	1.00e-170	592.00
IUUC-Apl-004208	Anas platyrhynchos	95.14	4.00e-136	476.00
IUUC-Aca-004661	Anolis carolinensis	83.44	4.00e-140	490.00
IUUC-Ath-007649	Arabidopsis thaliana	42.50	2.00e-12	67.00
IUUC-Ame-010610	Astyanax mexicanus	72.21	1.00e-138	486.00
IUUC-Bta-012606	Bos taurus	99.08	1.00e-171	595.00
IUUC-Cja-019482	Callithrix jacchus	99.68	0.00e+00	629.00
IUUC-Cfa-020482	Canis familiaris	98.77	1.00e-170	592.00
IUUC-Cpo-022061	Cavia porcellus	99.68	0.00e+00	629.00
IUUC-Csa-024102	Chlorocebus sabaeus	95.40	0.00e+00	872.00
IUUC-Cho-025081	Choloepus hoffmanni	81.93	7.00e-113	399.00
IUUC-Cin-025612	Ciona intestinalis	49.07	2.00e-52	199.00
IUUC-Dre-027929	Danio rerio	79.75	1.00e-142	498.00
IUUC-Dno-029797	Dasypus novemcinctus	98.09	0.00e+00	648.00
IUUC-Dor-030256	Dipodomys ordii	96.50	3.00e-169	587.00
IUUC-Dme-031904	Drosophila melanogaster	45.02	1.00e-52	202.00
IUUC-Ete-033148	Echinops telfairi	64.71	3.00e-83	301.00
IUUC-Eca-033318	Equus caballus	99.39	4.00e-172	596.00
IUUC-Eeu-034547	Erinaceus europaeus	86.31	2.00e-150	525.00
IUUC-Fca-035866	Felis catus	99.39	1.00e-171	595.00
IUUC-Fal-036660	Ficedula albicollis	96.01	3.00e-161	560.00
IUUC-Gmo-039341	Gadus morhua	82.31	6.00e-126	443.00
IUUC-Gga-040611	Gallus gallus	95.54	1.00e-166	578.00
IUUC-Gac-041888	Gasterosteus aculeatus	72.49	4.00e-129	454.00
IUUC-Gma-042798	Glycine max	39.51	5.00e-12	65.90
IUUC-Ggo-045027	Gorilla gorilla	100.00	0.00e+00	630.00
IUUC-Hsa-045665	Homo sapiens	99.57	0.00e+00	924.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	99.36	2.00e-179	621.00
IUUC-Lch-049714	Latimeria chalumnae	86.24	1.00e-164	572.00
IUUC-Loc-052161	Lepisosteus oculatus	81.35	3.00e-144	504.00
IUUC-Laf-054108	Loxodonta africana	97.80	2.00e-179	621.00
IUUC-Meu-056709	Macropus eugenii	97.85	1.00e-174	605.00
IUUC-Mtr-058158	Medicago truncatula	43.42	4.00e-10	57.00
IUUC-Mga-060104	Meleagris gallopavo	92.77	2.00e-120	424.00
IUUC-Mmr-061191	Microcebus murinus	97.59	0.00e+00	908.00
IUUC-Mdo-062711	Monodelphis domestica	93.17	4.00e-154	536.00
IUUC-Mmu-064255	Mus musculus	95.22	2.00e-167	581.00
IUUC-Mpu-066466	Mustela putorius furo	98.47	1.00e-170	592.00
IUUC-Mlu-067622	Myotis lucifugus	99.36	0.00e+00	627.00
IUUC-Nle-069253	Nomascus leucogenys	93.22	0.00e+00	851.00
IUUC-Opr-070511	Ochotona princeps	99.04	4.00e-180	623.00
IUUC-Ont-072177	Oreochromis niloticus	84.23	7.00e-130	456.00
IUUC-Oan-073336	Ornithorhynchus anatinus	97.55	5.00e-172	596.00
IUUC-Ocu-074113	Oryctolagus cuniculus	99.36	3.00e-171	594.00
IUUC-Oba-075690	Oryza barthii	42.25	6.00e-12	65.10
IUUC-Ogl-077513	Oryza glaberrima	42.25	7.00e-12	65.50
IUUC-Ogu-078755	Oryza glumaepatula	42.25	8.00e-12	65.10
IUUC-Oni-082398	Oryza nivara	42.25	7.00e-12	65.50
IUUC-Oru-084965	Oryza rufipogon	42.25	7.00e-12	65.50
IUUC-Osa-086282	Oryza sativa	42.25	4.00e-12	65.90
IUUC-Ola-087057	Oryzias latipes	85.19	4.00e-124	437.00
IUUC-Oga-088346	Otolemur garnettii	100.00	0.00e+00	630.00
IUUC-Oar-089843	Ovis aries	99.08	1.00e-171	595.00
IUUC-Ptr-090486	Pan troglodytes	100.00	0.00e+00	630.00
IUUC-Pan-092667	Papio anubis	94.83	0.00e+00	794.00
IUUC-Psi-093469	Pelodiscus sinensis	95.40	9.00e-174	602.00
IUUC-Pma-094481	Petromyzon marinus	74.04	3.00e-90	323.00
IUUC-Pfo-097156	Poecilia formosa	80.41	2.00e-133	468.00
IUUC-Pab-097670	Pongo abelii	100.00	0.00e+00	630.00
IUUC-Pop-099100	Populus trichocarpa	37.65	1.00e-12	67.40
IUUC-Pva-102800	Pteropus vampyrus	100.00	0.00e+00	630.00
IUUC-Rno-105128	Rattus norvegicus	94.59	1.00e-170	592.00
IUUC-Sha-106747	Sarcophilus harrisii	97.85	2.00e-163	568.00
IUUC-Sar-113416	Sorex araneus	99.36	0.00e+00	627.00
IUUC-Ssc-115864	Sus scrofa	99.68	0.00e+00	630.00
IUUC-Tgu-116851	Taeniopygia guttata	95.14	9.00e-137	479.00
IUUC-Tru-117698	Takifugu rubripes	86.18	7.00e-125	439.00
IUUC-Tsy-119590	Tarsius syrichta	99.36	0.00e+00	627.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.85	6.00e-129	453.00
IUUC-Tae-123760	Triticum aestivum	37.21	5.00e-12	65.90
IUUC-Tur-126396	Triticum urartu	37.21	6.00e-12	65.50
IUUC-Tbe-127790	Tupaia belangeri	99.68	0.00e+00	629.00
IUUC-Ttr-129316	Tursiops truncatus	99.39	0.00e+00	627.00
IUUC-Vpa-130669	Vicugna pacos	99.69	2.00e-172	597.00
IUUC-Xtr-131912	Xenopus tropicalis	87.77	4.00e-148	517.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence