iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090628

Ensembl Protein ID

ENSPTRP00000027058.3

UniProt Accession

H2QNY2; H2QNY2_PANTR

Genbank Protein ID

JAA05853.1; JAA17677.1; JAA31972.1; JAA37134.1

Protein Name

B-cell CLL/lymphoma 6

Genbank Nucleotide ID

AACZ03026861; GABF01004468; GABD01001128; GABE01007605

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000015728.4	ENSPTRT00000029314.3	ENSPTRP00000027058.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.10e-14	53.1	32	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv++vv +e+f+ahk vL+a+S  Fy+ f+ +l+ +   + ++++ ++ pe f  ll+F+Yt++l++ 
   Q: 32   TDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCN--LSVINLDpEINPEGFCILLDFMYTSRLNLR 98
           7**********************************76..699999988*****************9875 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL MACSGLFYSI 60
FTDQLKCNLS VINLDPEINP EGFCILLDFM YTSRLNLREG NIMAVMATAM YLQMEHVVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCATCGTCT TGGGCCCGGG GAGGGAGAGC CACCTTCAGG CCCCTCGAGC CTCGAACCGG 60
AACCTCCAAA TCCGAGACGC TCTGCTTATG AGGACCTCGA AATATGCCGG CCAGTGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0042127--P:regulation of cell proliferation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

KEGG

ptr:460926

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	96.05	0.00e+00	1366.00
IUUC-Atr-002779	Amborella trichopoda	34.44	1.00e-05	45.10
IUUC-Apl-003263	Anas platyrhynchos	78.48	0.00e+00	1132.00
IUUC-Ame-010714	Astyanax mexicanus	58.95	0.00e+00	805.00
IUUC-Bta-012576	Bos taurus	95.33	0.00e+00	1343.00
IUUC-Cja-018906	Callithrix jacchus	97.73	0.00e+00	1403.00
IUUC-Cfa-021058	Canis familiaris	94.59	0.00e+00	1345.00
IUUC-Cpo-022328	Cavia porcellus	95.89	0.00e+00	1382.00
IUUC-Csa-023942	Chlorocebus sabaeus	98.73	0.00e+00	1418.00
IUUC-Cho-024599	Choloepus hoffmanni	90.72	0.00e+00	776.00
IUUC-Cin-025470	Ciona intestinalis	80.99	8.00e-60	225.00
IUUC-Csv-025860	Ciona savignyi	82.11	9.00e-60	224.00
IUUC-Dre-027605	Danio rerio	60.39	0.00e+00	828.00
IUUC-Dno-029476	Dasypus novemcinctus	89.57	0.00e+00	1300.00
IUUC-Dor-030724	Dipodomys ordii	95.04	0.00e+00	1340.00
IUUC-Dme-031902	Drosophila melanogaster	42.39	6.00e-14	72.40
IUUC-Ete-032678	Echinops telfairi	91.22	0.00e+00	1281.00
IUUC-Eca-034377	Equus caballus	96.46	0.00e+00	1373.00
IUUC-Eeu-034532	Erinaceus europaeus	91.39	0.00e+00	847.00
IUUC-Fca-036465	Felis catus	96.60	0.00e+00	1378.00
IUUC-Fal-036977	Ficedula albicollis	78.57	0.00e+00	1149.00
IUUC-Gmo-039515	Gadus morhua	80.50	1.00e-113	402.00
IUUC-Gga-040505	Gallus gallus	78.76	0.00e+00	1139.00
IUUC-Gac-041393	Gasterosteus aculeatus	59.25	0.00e+00	807.00
IUUC-Gma-043945	Glycine max	32.58	7.00e-05	42.70
IUUC-Ggo-044500	Gorilla gorilla	99.72	0.00e+00	1433.00
IUUC-Hsa-046648	Homo sapiens	99.72	0.00e+00	1437.00
IUUC-Itr-048732	Ictidomys tridecemlineatus	92.50	0.00e+00	1317.00
IUUC-Lch-050387	Latimeria chalumnae	58.00	0.00e+00	751.00
IUUC-Loc-052103	Lepisosteus oculatus	62.24	0.00e+00	863.00
IUUC-Laf-053636	Loxodonta africana	95.34	0.00e+00	1378.00
IUUC-Mcc-055290	Macaca mulatta	98.73	0.00e+00	1422.00
IUUC-Meu-055910	Macropus eugenii	79.92	0.00e+00	1162.00
IUUC-Mga-059925	Meleagris gallopavo	78.34	0.00e+00	1126.00
IUUC-Mmr-060855	Microcebus murinus	96.74	0.00e+00	1374.00
IUUC-Mmu-063292	Mus musculus	94.91	0.00e+00	1331.00
IUUC-Mpu-066598	Mustela putorius furo	95.61	0.00e+00	1345.00
IUUC-Mlu-067370	Myotis lucifugus	94.49	0.00e+00	1328.00
IUUC-Nle-069870	Nomascus leucogenys	98.87	0.00e+00	1423.00
IUUC-Opr-070986	Ochotona princeps	92.92	0.00e+00	1300.00
IUUC-Ont-072475	Oreochromis niloticus	59.80	0.00e+00	775.00
IUUC-Oan-073596	Ornithorhynchus anatinus	84.69	0.00e+00	1192.00
IUUC-Ocu-073970	Oryctolagus cuniculus	95.20	0.00e+00	1381.00
IUUC-Ola-087102	Oryzias latipes	60.00	0.00e+00	812.00
IUUC-Oga-088873	Otolemur garnettii	96.05	0.00e+00	1383.00
IUUC-Oar-090083	Ovis aries	90.08	0.00e+00	1249.00
IUUC-Pan-092324	Papio anubis	98.31	0.00e+00	1411.00
IUUC-Psi-093695	Pelodiscus sinensis	79.61	0.00e+00	1108.00
IUUC-Pfo-096460	Poecilia formosa	58.38	0.00e+00	793.00
IUUC-Pab-098012	Pongo abelii	99.86	0.00e+00	1439.00
IUUC-Pca-100127	Procavia capensis	93.47	0.00e+00	1251.00
IUUC-Pva-102830	Pteropus vampyrus	94.62	0.00e+00	1343.00
IUUC-Rno-105752	Rattus norvegicus	95.33	0.00e+00	1335.00
IUUC-Sha-107259	Sarcophilus harrisii	83.19	0.00e+00	1193.00
IUUC-Sar-113610	Sorex araneus	92.09	0.00e+00	1062.00
IUUC-Ssc-115327	Sus scrofa	95.18	0.00e+00	1360.00
IUUC-Tgu-116457	Taeniopygia guttata	79.61	0.00e+00	1164.00
IUUC-Tru-118520	Takifugu rubripes	59.00	0.00e+00	798.00
IUUC-Tni-119969	Tetraodon nigroviridis	59.41	0.00e+00	797.00
IUUC-Tbe-127327	Tupaia belangeri	90.93	0.00e+00	1283.00
IUUC-Ttr-129204	Tursiops truncatus	93.48	0.00e+00	1310.00
IUUC-Xtr-132937	Xenopus tropicalis	67.28	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence