iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001367

Ensembl Protein ID

ENSAMEP00000009220.1

UniProt Accession

G1LQ89; G1LQ89_AILME

Genbank Protein ID

ENSAMEP00000009220

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01057700

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000008746.1	ENSAMET00000009617.1	ENSAMEP00000009220.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	48.15	2.00e-08	57.40	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	90.86	3.00e-168	588.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	90.86	3.00e-168	588.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	87.97	2.00e-169	592.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	88.24	3.00e-167	584.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

HNLDEDGDLV AFSSDEELRM AMSYVKDDIF RIYIKEKKEC RRDHRPPCAQ EAPRGLVHPN 60
VICDGCNGPV VGTRYKCSVC PDYDLCAACE GKGLHREHSK LVFPAAFGPF SEGFSHSRWL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAACCTAG ATGAGGACGG AGACTTGGTG GCCTTTTCCA GTGACGAGGA ACTGCGCATG 60
GCAATGTCCT ACGTGAAGGA TGACATCTTC CGGATTTACA TCAAAGGTAA GGGTCTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003897	Anas platyrhynchos	57.99	2.00e-115	409.00
IUUC-Aca-004699	Anolis carolinensis	49.48	2.00e-85	309.00
IUUC-Ame-010982	Astyanax mexicanus	45.37	6.00e-65	241.00
IUUC-Bta-012634	Bos taurus	90.59	0.00e+00	651.00
IUUC-Cel-018660	Caenorhabditis elegans	43.75	5.00e-11	60.50
IUUC-Cja-019684	Callithrix jacchus	89.78	5.00e-178	617.00
IUUC-Cfa-020573	Canis familiaris	91.42	3.00e-153	534.00
IUUC-Cpo-021425	Cavia porcellus	80.00	6.00e-155	540.00
IUUC-Csa-023968	Chlorocebus sabaeus	90.03	2.00e-174	604.00
IUUC-Cho-024596	Choloepus hoffmanni	83.23	2.00e-52	199.00
IUUC-Cin-025557	Ciona intestinalis	28.57	8.00e-14	71.20
IUUC-Csv-025974	Ciona savignyi	57.50	6.00e-09	54.70
IUUC-Cne-027045	Cryptococcus neoformans	50.98	9.00e-10	59.70
IUUC-Dre-028621	Danio rerio	45.48	4.00e-84	305.00
IUUC-Dno-029060	Dasypus novemcinctus	87.80	0.00e+00	647.00
IUUC-Dor-030547	Dipodomys ordii	89.81	5.00e-111	394.00
IUUC-Dme-031659	Drosophila melanogaster	48.15	2.00e-09	57.80
IUUC-Ete-033201	Echinops telfairi	79.03	4.00e-159	553.00
IUUC-Eca-033456	Equus caballus	90.74	0.00e+00	673.00
IUUC-Eeu-035157	Erinaceus europaeus	85.14	1.00e-170	592.00
IUUC-Fca-035403	Felis catus	94.89	0.00e+00	652.00
IUUC-Fal-036798	Ficedula albicollis	58.94	1.00e-118	419.00
IUUC-Gmo-039619	Gadus morhua	44.88	4.00e-43	168.00
IUUC-Gga-040137	Gallus gallus	57.68	3.00e-117	414.00
IUUC-Gac-042410	Gasterosteus aculeatus	47.51	5.00e-84	304.00
IUUC-Ggo-044690	Gorilla gorilla	91.40	5.00e-176	610.00
IUUC-Hsa-046390	Homo sapiens	90.86	2.00e-175	608.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	91.13	0.00e+00	671.00
IUUC-Lch-049658	Latimeria chalumnae	49.61	1.00e-98	353.00
IUUC-Loc-052589	Lepisosteus oculatus	49.61	2.00e-98	352.00
IUUC-Laf-053746	Loxodonta africana	77.48	2.00e-153	535.00
IUUC-Mcc-055635	Macaca mulatta	90.30	2.00e-176	611.00
IUUC-Meu-056528	Macropus eugenii	50.94	3.00e-93	335.00
IUUC-Mga-059458	Meleagris gallopavo	58.12	9.00e-117	413.00
IUUC-Mvi-060347	Microbotryum violaceum	51.16	1.00e-07	52.80
IUUC-Mmr-061539	Microcebus murinus	83.53	6.00e-111	394.00
IUUC-Mdo-063083	Monodelphis domestica	64.32	1.00e-126	446.00
IUUC-Mmu-063589	Mus musculus	86.90	0.00e+00	649.00
IUUC-Mpu-065727	Mustela putorius furo	95.69	0.00e+00	672.00
IUUC-Mlu-067026	Myotis lucifugus	87.37	0.00e+00	627.00
IUUC-Nle-069356	Nomascus leucogenys	58.59	1.00e-87	316.00
IUUC-Opr-071091	Ochotona princeps	70.23	3.00e-85	308.00
IUUC-Ont-071864	Oreochromis niloticus	48.66	1.00e-90	326.00
IUUC-Oan-073308	Ornithorhynchus anatinus	64.95	2.00e-128	451.00
IUUC-Ocu-074110	Oryctolagus cuniculus	89.33	4.00e-180	624.00
IUUC-Ola-086944	Oryzias latipes	47.25	8.00e-40	156.00
IUUC-Oga-088869	Otolemur garnettii	89.04	1.00e-179	622.00
IUUC-Oar-089857	Ovis aries	90.67	0.00e+00	649.00
IUUC-Ptr-091640	Pan troglodytes	90.86	2.00e-175	608.00
IUUC-Pan-092831	Papio anubis	90.88	2.00e-176	611.00
IUUC-Psi-093925	Pelodiscus sinensis	58.96	2.00e-115	409.00
IUUC-Pma-094576	Petromyzon marinus	32.08	4.00e-22	99.40
IUUC-Pfo-097297	Poecilia formosa	46.80	6.00e-82	298.00
IUUC-Pab-098725	Pongo abelii	79.84	1.00e-151	529.00
IUUC-Pca-101106	Procavia capensis	88.71	3.00e-170	591.00
IUUC-Pva-102710	Pteropus vampyrus	87.93	6.00e-163	566.00
IUUC-Rno-105539	Rattus norvegicus	88.24	0.00e+00	664.00
IUUC-Sha-107469	Sarcophilus harrisii	59.59	4.00e-121	427.00
IUUC-Ssc-115526	Sus scrofa	91.67	0.00e+00	629.00
IUUC-Tgu-117194	Taeniopygia guttata	60.68	2.00e-117	415.00
IUUC-Tru-117896	Takifugu rubripes	50.80	2.00e-90	325.00
IUUC-Tni-119943	Tetraodon nigroviridis	49.60	3.00e-80	292.00
IUUC-Ttr-128676	Tursiops truncatus	90.86	0.00e+00	670.00
IUUC-Vda-129812	Verticillium dahliae	36.36	1.00e-07	51.60
IUUC-Vpa-130319	Vicugna pacos	94.00	1.00e-55	209.00
IUUC-Xtr-132907	Xenopus tropicalis	54.62	2.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence