iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000009554.6	ENSGALT00000015553.5	ENSGALP00000015537.5
ENSGALG00000009554.6	ENSGALT00000078753.1	ENSGALP00000053980.1
ENSGALG00000009554.6	ENSGALT00000067980.2	ENSGALP00000051031.1
ENSGALG00000009554.6	ENSGALT00000078303.1	ENSGALP00000056277.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.10e-21	75.9	62	129
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.20e-11	41.4	162	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e+ ah++vLaa+S++F+a+f++e++es+  +++ ik+v+   +r l++++Yt +++ +e
   Q: 62   CDVTIVAEDMEIAAHRVVLAACSPYFHAMFTGEMSESR-AKRIRIKEVDGWTLRILIDYIYTAEIQVTE 129
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
            Nclgi++fAd++ c+dL  +a++++++hF
   Q: 162  VNCLGIRAFADMHACTDLLNKANTYAEQHF 191
           6***************************** PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MTTLSSAEDA TEACRCTKLC HQKPLDLKDD NTEIHCPVTV NPWHMKKAFK VMNELRSQNL 60
LCDVTIVAED MEIAAHRVVL AACSPYFHAM FTGEMSESRA KRIRIKEVDG WTLRILIDYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTACCT TATCCAGTGC AGAGGATGCA ACTGAAGCCT GCAGGTAAGA GACTGAAAGC 60
CTGGGCCACC TCTTTCACAG ATGTCTCAGA TACACATATG AGAAATCCAA ACCTTTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0003779--F:actin binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	92.47	0.00e+00	1102.00
IUUC-Apl-003260	Anas platyrhynchos	99.14	0.00e+00	1155.00
IUUC-Aca-005143	Anolis carolinensis	88.01	0.00e+00	1087.00
IUUC-Cja-018942	Callithrix jacchus	92.47	0.00e+00	1103.00
IUUC-Cfa-020886	Canis familiaris	92.82	0.00e+00	1110.00
IUUC-Cpo-022543	Cavia porcellus	92.64	0.00e+00	1106.00
IUUC-Csa-023088	Chlorocebus sabaeus	92.81	0.00e+00	1107.00
IUUC-Dre-028082	Danio rerio	82.02	0.00e+00	985.00
IUUC-Dno-029873	Dasypus novemcinctus	90.49	0.00e+00	1085.00
IUUC-Dor-030460	Dipodomys ordii	73.63	0.00e+00	806.00
IUUC-Dse-031229	Dothistroma septosporum	33.72	5.00e-08	50.80
IUUC-Dme-032172	Drosophila melanogaster	61.72	0.00e+00	674.00
IUUC-Eca-033798	Equus caballus	91.95	0.00e+00	1100.00
IUUC-Eeu-034824	Erinaceus europaeus	85.27	0.00e+00	921.00
IUUC-Fca-036455	Felis catus	92.82	0.00e+00	1110.00
IUUC-Fal-037293	Ficedula albicollis	98.02	0.00e+00	1082.00
IUUC-Gmo-038811	Gadus morhua	78.15	0.00e+00	863.00
IUUC-Gac-041979	Gasterosteus aculeatus	80.24	0.00e+00	866.00
IUUC-Ggo-044620	Gorilla gorilla	88.03	0.00e+00	1048.00
IUUC-Hsa-046265	Homo sapiens	92.64	0.00e+00	1106.00
IUUC-Lch-049939	Latimeria chalumnae	83.56	0.00e+00	980.00
IUUC-Loc-052780	Lepisosteus oculatus	86.82	0.00e+00	1036.00
IUUC-Laf-053800	Loxodonta africana	92.64	0.00e+00	1107.00
IUUC-Mcc-055732	Macaca mulatta	91.78	0.00e+00	1095.00
IUUC-Meu-056011	Macropus eugenii	92.99	0.00e+00	1025.00
IUUC-Mmr-061067	Microcebus murinus	91.11	0.00e+00	1088.00
IUUC-Mdo-062977	Monodelphis domestica	92.29	0.00e+00	1098.00
IUUC-Mmu-064035	Mus musculus	91.67	0.00e+00	1083.00
IUUC-Mpu-066726	Mustela putorius furo	92.99	0.00e+00	1111.00
IUUC-Mlu-067020	Myotis lucifugus	92.48	0.00e+00	1106.00
IUUC-Nle-069456	Nomascus leucogenys	92.48	0.00e+00	1107.00
IUUC-Opr-071130	Ochotona princeps	83.05	0.00e+00	966.00
IUUC-Ont-072219	Oreochromis niloticus	80.85	0.00e+00	923.00
IUUC-Oan-073699	Ornithorhynchus anatinus	91.14	0.00e+00	941.00
IUUC-Ocu-074045	Oryctolagus cuniculus	92.47	0.00e+00	1104.00
IUUC-Oga-088494	Otolemur garnettii	92.48	0.00e+00	1107.00
IUUC-Oar-089645	Ovis aries	92.47	0.00e+00	1104.00
IUUC-Ptr-091063	Pan troglodytes	92.64	0.00e+00	1105.00
IUUC-Psi-093946	Pelodiscus sinensis	93.36	0.00e+00	1124.00
IUUC-Pma-094177	Petromyzon marinus	75.89	0.00e+00	801.00
IUUC-Pfo-096817	Poecilia formosa	80.51	0.00e+00	941.00
IUUC-Pab-097768	Pongo abelii	92.64	0.00e+00	1105.00
IUUC-Pca-100607	Procavia capensis	75.90	0.00e+00	773.00
IUUC-Pva-102218	Pteropus vampyrus	86.99	0.00e+00	1025.00
IUUC-Rno-105250	Rattus norvegicus	91.95	0.00e+00	1097.00
IUUC-Sce-106241	Saccharomyces cerevisiae	22.50	6.60e+00	25.40
IUUC-Sar-113249	Sorex araneus	92.17	0.00e+00	1082.00
IUUC-Sre-115091	Sporisorium reilianum	53.12	4.50e-01	30.00
IUUC-Ssc-115423	Sus scrofa	92.48	0.00e+00	1107.00
IUUC-Tgu-117050	Taeniopygia guttata	97.26	0.00e+00	1138.00
IUUC-Tru-118239	Takifugu rubripes	79.73	0.00e+00	961.00
IUUC-Tsy-119377	Tarsius syrichta	79.11	0.00e+00	945.00
IUUC-Tni-120122	Tetraodon nigroviridis	80.47	0.00e+00	865.00
IUUC-Vpa-130707	Vicugna pacos	89.06	0.00e+00	834.00
IUUC-Xtr-132035	Xenopus tropicalis	85.20	0.00e+00	1043.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence