iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059343

UUCD1 version

UUC-MeG-00156

Ensembl Protein ID

ENSMGAP00000002907.1

UniProt Accession

G1MW22; G1MW22_MELGA

Protein Name

Uncharacterized protein

Gene Name

TRIM32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003227.1	ENSMGAT00000003597.1	ENSMGAP00000002907.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.50e-07	31.6	21	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg...plvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iC+e+f ++   p++l CgH+++++Cl+k+      s + +rCP C
   Q: 21   CPICMESFTEEhlrPKLLHCGHTICKQCLEKL---LATSINGIRCPFC 65
           ********776677999************888...66799******** PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VETMASAPQL NSDALREVLE CPICMESFTE EHLRPKLLHC GHTICKQCLE KLLATSINGI 60
RCPFCSKITR IKTLAQLTDN LTVLKIIDTT GLGEVVGLLM CKVCGRRLPR HFCKSCGLVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAAACCA TGGCTTCTGC CCCTCAGCTC AACTCGGATG CACTCCGAGA GGTCCTGGAG 60
TGCCCCATTT GCATGGAGTC CTTTACTGAG GAGCACCTGA GACCCAAGCT CTTACACTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001258--NHL_repeat
IPR013017--NHL_repeat_subgr
IPR033569--TRIM32
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51125--NHL
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01436--NHL
PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005863--C:striated muscle myosin thick filament
GO:0003723--F:RNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007014--P:actin ubiquitination
GO:0061564--P:axon development
GO:0045444--P:fat cell differentiation
GO:0045087--P:innate immune response
GO:0046716--P:muscle cell cellular homeostasis
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0045787--P:positive regulation of cell cycle
GO:0030307--P:positive regulation of cell growth
GO:0030335--P:positive regulation of cell migration
GO:1903886--P:positive regulation of chemokine (C-C motif) ligand 20 production
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1903883--P:positive regulation of interleukin-17-mediated signaling pathway
GO:0045666--P:positive regulation of neuron differentiation
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045732--P:positive regulation of protein catabolic process
GO:0045862--P:positive regulation of proteolysis
GO:0051155--P:positive regulation of striated muscle cell differentiation
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0034612--P:response to tumor necrosis factor
GO:0009411--P:response to UV
GO:0001894--P:tissue homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000568	Aegilops tauschii	36.51	4.00e-06	44.30
IUUC-Aml-001554	Ailuropoda melanoleuca	78.98	0.00e+00	1018.00
IUUC-Aca-004290	Anolis carolinensis	83.44	0.00e+00	1083.00
IUUC-Aly-006480	Arabidopsis lyrata	35.62	3.00e-09	57.80
IUUC-Ame-011474	Astyanax mexicanus	56.89	0.00e+00	760.00
IUUC-Bta-013335	Bos taurus	76.82	0.00e+00	987.00
IUUC-Bol-015127	Brassica oleracea	36.36	8.00e-10	56.60
IUUC-Cel-018405	Caenorhabditis elegans	26.42	6.00e-12	64.30
IUUC-Cja-019836	Callithrix jacchus	79.26	0.00e+00	1029.00
IUUC-Cfa-020126	Canis familiaris	78.98	0.00e+00	1018.00
IUUC-Cpo-021619	Cavia porcellus	79.26	0.00e+00	1029.00
IUUC-Csa-023381	Chlorocebus sabaeus	79.44	0.00e+00	1023.00
IUUC-Cho-024696	Choloepus hoffmanni	77.88	0.00e+00	995.00
IUUC-Dre-028768	Danio rerio	59.06	0.00e+00	786.00
IUUC-Dno-029162	Dasypus novemcinctus	79.29	0.00e+00	1022.00
IUUC-Dor-030490	Dipodomys ordii	79.63	0.00e+00	1010.00
IUUC-Ete-032250	Echinops telfairi	77.59	0.00e+00	995.00
IUUC-Eca-033392	Equus caballus	79.44	0.00e+00	1022.00
IUUC-Fca-035512	Felis catus	79.29	0.00e+00	1017.00
IUUC-Fal-036745	Ficedula albicollis	90.28	0.00e+00	1142.00
IUUC-Fox-038006	Fusarium oxysporum	39.68	2.00e-05	42.70
IUUC-Gmo-038737	Gadus morhua	54.42	0.00e+00	709.00
IUUC-Gga-040258	Gallus gallus	95.52	0.00e+00	1207.00
IUUC-Gac-041657	Gasterosteus aculeatus	56.84	0.00e+00	728.00
IUUC-Ggo-045473	Gorilla gorilla	80.06	0.00e+00	1027.00
IUUC-Hsa-046653	Homo sapiens	80.06	0.00e+00	1026.00
IUUC-Hvu-047109	Hordeum vulgare	38.10	3.00e-06	45.10
IUUC-Itr-048947	Ictidomys tridecemlineatus	79.42	0.00e+00	1028.00
IUUC-Lch-049791	Latimeria chalumnae	68.41	0.00e+00	884.00
IUUC-Loc-052573	Lepisosteus oculatus	62.75	0.00e+00	817.00
IUUC-Laf-054514	Loxodonta africana	79.44	0.00e+00	1025.00
IUUC-Mcc-055244	Macaca mulatta	79.44	0.00e+00	1023.00
IUUC-Meu-056655	Macropus eugenii	73.61	0.00e+00	964.00
IUUC-Mtr-058731	Medicago truncatula	36.00	6.00e-11	62.00
IUUC-Mmr-061774	Microcebus murinus	79.29	0.00e+00	1022.00
IUUC-Mmu-063743	Mus musculus	78.70	0.00e+00	1016.00
IUUC-Mpu-066801	Mustela putorius furo	79.44	0.00e+00	1022.00
IUUC-Nle-069880	Nomascus leucogenys	79.75	0.00e+00	1026.00
IUUC-Ont-071805	Oreochromis niloticus	55.59	0.00e+00	715.00
IUUC-Oan-073221	Ornithorhynchus anatinus	75.12	0.00e+00	922.00
IUUC-Ocu-074609	Oryctolagus cuniculus	79.13	0.00e+00	998.00
IUUC-Olo-080692	Oryza longistaminata	33.72	9.00e-07	47.00
IUUC-Osa-086244	Oryza sativa	34.85	4.00e-07	48.50
IUUC-Oga-088597	Otolemur garnettii	79.75	0.00e+00	1027.00
IUUC-Oar-089322	Ovis aries	78.97	4.00e-180	624.00
IUUC-Ptr-091638	Pan troglodytes	80.06	0.00e+00	1028.00
IUUC-Pan-092001	Papio anubis	79.44	0.00e+00	1023.00
IUUC-Psi-093112	Pelodiscus sinensis	87.19	0.00e+00	1135.00
IUUC-Ppa-095766	Physcomitrella patens	39.19	5.00e-12	63.90
IUUC-Pfo-097226	Poecilia formosa	55.98	0.00e+00	741.00
IUUC-Pab-098115	Pongo abelii	79.60	0.00e+00	1025.00
IUUC-Pte-104037	Pyrenophora teres	36.54	8.00e-07	47.80
IUUC-Rno-104950	Rattus norvegicus	79.01	0.00e+00	1021.00
IUUC-Sha-106842	Sarcophilus harrisii	76.12	0.00e+00	978.00
IUUC-Smo-109517	Selaginella moellendorffii	37.31	2.00e-10	56.60
IUUC-Ssc-115577	Sus scrofa	79.29	0.00e+00	1020.00
IUUC-Tgu-116636	Taeniopygia guttata	90.14	0.00e+00	1144.00
IUUC-Tsy-119479	Tarsius syrichta	79.60	0.00e+00	1026.00
IUUC-Tni-120872	Tetraodon nigroviridis	54.40	0.00e+00	699.00
IUUC-Tae-124848	Triticum aestivum	36.51	5.00e-06	44.30
IUUC-Tur-126036	Triticum urartu	36.51	4.00e-06	44.70
IUUC-Ttr-129170	Tursiops truncatus	79.44	0.00e+00	1035.00
IUUC-Xtr-132839	Xenopus tropicalis	68.82	0.00e+00	909.00
IUUC-Xma-133992	Xiphophorus maculatus	55.71	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence