iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000020845.3	ENSCJAT00000040977.2	ENSCJAP00000038791.2
ENSCJAG00000020845.3	ENSCJAT00000040974.2	ENSCJAP00000038788.2
ENSCJAG00000020845.3	ENSCJAT00000061271.1	ENSCJAP00000045088.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.80e-28	97.8	273	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 1    ekvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           +kvC  C+++g+d+ ++++Ce C++ +H  Clk++  eelp ++ w C+ Cr +
   Q: 273  CKVCQACRKPGNDS-KMLVCETCDKGYHTFCLKPP-MEELPAHS-WKCKACRVC 323
           57999999999987.6*******************.*******8.******965 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MDSQKLPGED KDSEPAADEP AASEDPGATE SDLPNPHVGE VSVPSSGSPR LQDTPQDCSG 60
GPVRRCALCN CGEPSLHGQR ELQRFELPFD WPRCPVVSPR GSPGPNEAVL PSEDLSQIGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGCC AGAAGCTGCC TGGTGAGGAT AAAGATTCGG AACCGGCAGG TGAGTAGGAC 60
AGATTCTGTG TTTGCTTTTA GATTTCATGG GCAACCTTAC AATTCTGGTC CTGGCACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0008284--P:positive regulation of cell proliferation
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001806	Ailuropoda melanoleuca	93.06	0.00e+00	3708.00
IUUC-Aca-005364	Anolis carolinensis	52.71	0.00e+00	1224.00
IUUC-Ame-010612	Astyanax mexicanus	81.00	0.00e+00	1010.00
IUUC-Bta-013011	Bos taurus	91.35	0.00e+00	3588.00
IUUC-Cfa-021131	Canis familiaris	92.45	0.00e+00	3704.00
IUUC-Cpo-021957	Cavia porcellus	89.95	0.00e+00	3798.00
IUUC-Csa-023722	Chlorocebus sabaeus	95.64	0.00e+00	3792.00
IUUC-Dno-029932	Dasypus novemcinctus	85.39	0.00e+00	2284.00
IUUC-Dor-030192	Dipodomys ordii	86.25	0.00e+00	1692.00
IUUC-Ete-032572	Echinops telfairi	86.29	0.00e+00	2003.00
IUUC-Eca-034166	Equus caballus	92.29	0.00e+00	743.00
IUUC-Eeu-034848	Erinaceus europaeus	91.94	0.00e+00	1324.00
IUUC-Fca-035424	Felis catus	92.88	0.00e+00	3730.00
IUUC-Fal-037179	Ficedula albicollis	65.90	0.00e+00	1146.00
IUUC-Gmo-038719	Gadus morhua	82.21	0.00e+00	911.00
IUUC-Gga-040815	Gallus gallus	57.26	0.00e+00	1491.00
IUUC-Gac-042436	Gasterosteus aculeatus	79.86	0.00e+00	997.00
IUUC-Ggo-044711	Gorilla gorilla	96.59	0.00e+00	3794.00
IUUC-Hsa-046567	Homo sapiens	96.60	0.00e+00	3865.00
IUUC-Itr-048510	Ictidomys tridecemlineatus	91.27	0.00e+00	3665.00
IUUC-Loc-051979	Lepisosteus oculatus	82.64	0.00e+00	1058.00
IUUC-Laf-054377	Loxodonta africana	91.08	0.00e+00	3623.00
IUUC-Mcc-055577	Macaca mulatta	94.70	0.00e+00	3746.00
IUUC-Meu-055992	Macropus eugenii	84.39	0.00e+00	1317.00
IUUC-Mmr-061772	Microcebus murinus	89.86	0.00e+00	3655.00
IUUC-Mdo-062876	Monodelphis domestica	83.26	0.00e+00	1141.00
IUUC-Mmu-063903	Mus musculus	86.51	0.00e+00	3536.00
IUUC-Mpu-066700	Mustela putorius furo	92.20	0.00e+00	3673.00
IUUC-Mlu-068180	Myotis lucifugus	91.82	0.00e+00	3732.00
IUUC-Nle-069362	Nomascus leucogenys	95.92	0.00e+00	3794.00
IUUC-Opr-070304	Ochotona princeps	87.54	0.00e+00	3434.00
IUUC-Ont-071881	Oreochromis niloticus	64.16	0.00e+00	1204.00
IUUC-Ocu-074053	Oryctolagus cuniculus	87.49	0.00e+00	3672.00
IUUC-Ola-086384	Oryzias latipes	61.77	0.00e+00	1170.00
IUUC-Oga-088450	Otolemur garnettii	92.06	0.00e+00	3840.00
IUUC-Oar-089975	Ovis aries	89.26	0.00e+00	1643.00
IUUC-Ptr-091073	Pan troglodytes	95.76	0.00e+00	3787.00
IUUC-Pan-092871	Papio anubis	92.45	0.00e+00	3882.00
IUUC-Pfo-097525	Poecilia formosa	80.11	0.00e+00	983.00
IUUC-Pab-097679	Pongo abelii	96.67	0.00e+00	3815.00
IUUC-Pca-100499	Procavia capensis	87.42	0.00e+00	2212.00
IUUC-Pva-102898	Pteropus vampyrus	92.61	0.00e+00	3608.00
IUUC-Rno-105660	Rattus norvegicus	87.92	0.00e+00	3548.00
IUUC-Sha-107431	Sarcophilus harrisii	80.78	0.00e+00	3056.00
IUUC-Sbi-113816	Sorghum bicolor	33.71	3.00e-13	70.90
IUUC-Ssc-115678	Sus scrofa	90.97	0.00e+00	3545.00
IUUC-Tru-117922	Takifugu rubripes	80.39	0.00e+00	1012.00
IUUC-Tsy-118905	Tarsius syrichta	87.89	0.00e+00	1666.00
IUUC-Tbe-127625	Tupaia belangeri	87.50	8.00e-159	556.00
IUUC-Ttr-129162	Tursiops truncatus	91.09	0.00e+00	2102.00
IUUC-Xtr-132455	Xenopus tropicalis	66.24	0.00e+00	1167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence