iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005005

Ensembl Protein ID

ENSACAP00000004057.3

UniProt Accession

G1KCK3; G1KCK3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

DNMBP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004166.3	ENSACAT00000004151.3	ENSACAP00000004057.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.10e-45	151.0	280	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++ly++ a ++ eL ++ Gd ++++     d gWl+g  el+g+rG+fP+ Fv+
   Q: 280  GIALYQFRALESSELDFEVGDRIRIV--GVLDDGWLEG--ELRGRRGIFPHRFVR 330
           579***********************..899*******..9************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MDRQAGGRAV LCEPAKKQRR RQQGTQCRGK IPRMEVGSVV RAIFDFCPSV SEELPLFVGD 60
VTEVLAVIDE FWLLGKKEGV TGQFPSSFVE LLYVPALNQG EKLFVCTSNF TSQAPGSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTCATAGT AGCAAACCTC GCTTTTCTCT GGTCCTACCA TGTTCACTTG TCTACAAATG 60
GCAAACTGAA AGCTATCTTA TCTTTACCTG GGTGTATTGT GGATCAGGGC ATTTGTGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	68.66	0.00e+00	1025.00
IUUC-Apl-003934	Anas platyrhynchos	74.25	0.00e+00	1207.00
IUUC-Ame-011361	Astyanax mexicanus	67.28	0.00e+00	851.00
IUUC-Bta-013210	Bos taurus	68.26	0.00e+00	1030.00
IUUC-Cel-018396	Caenorhabditis elegans	27.71	5.00e-31	130.00
IUUC-Cja-019104	Callithrix jacchus	66.87	0.00e+00	994.00
IUUC-Cfa-020960	Canis familiaris	67.39	0.00e+00	1027.00
IUUC-Cpo-022440	Cavia porcellus	75.99	0.00e+00	997.00
IUUC-Csa-023391	Chlorocebus sabaeus	68.99	0.00e+00	1036.00
IUUC-Cho-024795	Choloepus hoffmanni	59.60	0.00e+00	735.00
IUUC-Cin-025137	Ciona intestinalis	34.69	7.00e-33	133.00
IUUC-Cne-027023	Cryptococcus neoformans	29.18	6.00e-13	70.10
IUUC-Dre-027932	Danio rerio	65.95	0.00e+00	835.00
IUUC-Dno-029750	Dasypus novemcinctus	58.03	0.00e+00	1553.00
IUUC-Dor-031109	Dipodomys ordii	65.57	0.00e+00	991.00
IUUC-Ete-032660	Echinops telfairi	61.07	0.00e+00	860.00
IUUC-Eca-033433	Equus caballus	68.47	0.00e+00	1107.00
IUUC-Eeu-034929	Erinaceus europaeus	59.63	2.00e-153	537.00
IUUC-Fca-035859	Felis catus	75.44	0.00e+00	1003.00
IUUC-Fal-036653	Ficedula albicollis	61.68	0.00e+00	1654.00
IUUC-Gmo-038948	Gadus morhua	60.32	0.00e+00	738.00
IUUC-Gga-040279	Gallus gallus	61.92	0.00e+00	1662.00
IUUC-Gac-041641	Gasterosteus aculeatus	59.97	0.00e+00	801.00
IUUC-Ggo-044900	Gorilla gorilla	30.10	8.00e-67	248.00
IUUC-Hsa-046063	Homo sapiens	70.26	0.00e+00	1040.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	62.16	0.00e+00	1125.00
IUUC-Lch-049865	Latimeria chalumnae	56.54	0.00e+00	748.00
IUUC-Loc-051754	Lepisosteus oculatus	59.08	0.00e+00	991.00
IUUC-Laf-054037	Loxodonta africana	62.55	0.00e+00	1177.00
IUUC-Mcc-055002	Macaca mulatta	69.89	0.00e+00	1039.00
IUUC-Meu-056420	Macropus eugenii	64.33	0.00e+00	927.00
IUUC-Mga-059868	Meleagris gallopavo	62.49	0.00e+00	1660.00
IUUC-Mmr-060767	Microcebus murinus	63.29	0.00e+00	1148.00
IUUC-Mdo-061939	Monodelphis domestica	64.10	0.00e+00	1125.00
IUUC-Mmu-063980	Mus musculus	55.53	0.00e+00	1462.00
IUUC-Mpu-065913	Mustela putorius furo	73.79	0.00e+00	1030.00
IUUC-Mlu-067340	Myotis lucifugus	69.40	0.00e+00	1056.00
IUUC-Nle-069343	Nomascus leucogenys	70.50	0.00e+00	1037.00
IUUC-Opr-070694	Ochotona princeps	66.92	0.00e+00	1069.00
IUUC-Ont-071844	Oreochromis niloticus	62.16	0.00e+00	799.00
IUUC-Oan-073605	Ornithorhynchus anatinus	63.64	1.00e-26	114.00
IUUC-Ocu-074406	Oryctolagus cuniculus	68.47	0.00e+00	1108.00
IUUC-Ola-087343	Oryzias latipes	59.33	0.00e+00	687.00
IUUC-Oga-088847	Otolemur garnettii	63.08	0.00e+00	1129.00
IUUC-Oar-089817	Ovis aries	67.11	0.00e+00	1019.00
IUUC-Ptr-090508	Pan troglodytes	29.33	6.00e-67	248.00
IUUC-Pan-092104	Papio anubis	69.49	0.00e+00	1029.00
IUUC-Psi-094045	Pelodiscus sinensis	51.75	0.00e+00	686.00
IUUC-Pma-094663	Petromyzon marinus	43.05	7.00e-132	465.00
IUUC-Pfo-096714	Poecilia formosa	56.01	0.00e+00	809.00
IUUC-Pab-097918	Pongo abelii	60.31	0.00e+00	1436.00
IUUC-Pca-101096	Procavia capensis	49.63	0.00e+00	733.00
IUUC-Pva-102490	Pteropus vampyrus	58.15	0.00e+00	1429.00
IUUC-Rno-105908	Rattus norvegicus	62.88	0.00e+00	1090.00
IUUC-Sha-107509	Sarcophilus harrisii	71.64	0.00e+00	1045.00
IUUC-Ssc-115250	Sus scrofa	68.36	0.00e+00	1012.00
IUUC-Tru-118279	Takifugu rubripes	61.30	0.00e+00	849.00
IUUC-Tni-120459	Tetraodon nigroviridis	63.67	0.00e+00	719.00
IUUC-Tbe-127753	Tupaia belangeri	49.65	2.00e-102	367.00
IUUC-Ttr-129096	Tursiops truncatus	64.84	0.00e+00	1014.00
IUUC-Vpa-130643	Vicugna pacos	62.70	0.00e+00	890.00
IUUC-Xtr-131979	Xenopus tropicalis	54.61	0.00e+00	1506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence