iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020960

Ensembl Protein ID

ENSCAFP00000014051.3

UniProt Accession

E2RP94; E2RP94_CANLF

Genbank Protein ID

ENSCAFP00000014051

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03015466

Gene Name

DNMBP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009561.3	ENSCAFT00000015184.3	ENSCAFP00000014051.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-48	161.1	248	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            ++ly ++a + +eL ++ Gd+++++   + + gWl+g   l+g+ G+fP  Fv+ 
   Q: 248  GIALYRFQALEPNELDFEVGDKIRIL--GTLEDGWLEG--SLKGRTGIFPYRFVKL 299
           689***********************..88899*****..9*************85 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEAGSVVRAI FDFCPSVSEE LPLFVGDIIE VLAVVDEFWL LGKKEDVTGQ FPSSFVEIVT 60
IPSLKEGERL FVCISEFTSQ ELNSLPLHRG DLVILDDAPT ASWLQGRSCW GARGFFPSSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTATAAAAC ATGGAGGCTG GCTCAGTGGT TCGAGCCATC TTTGACTTCT GCCCCAGTGT 60
ATCAGAAGAA CTACCGCTCT TTGTGGGAGA TATTATTGAG GTGTTGGCAG TGGTGGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

KEGG

cfa:477794

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	88.63	0.00e+00	2525.00
IUUC-Apl-003934	Anas platyrhynchos	77.94	0.00e+00	1045.00
IUUC-Aca-005005	Anolis carolinensis	68.45	0.00e+00	1103.00
IUUC-Ame-011361	Astyanax mexicanus	58.95	0.00e+00	961.00
IUUC-Bta-013210	Bos taurus	83.76	0.00e+00	2368.00
IUUC-Cel-018396	Caenorhabditis elegans	27.00	2.00e-31	131.00
IUUC-Cja-019104	Callithrix jacchus	80.57	0.00e+00	2254.00
IUUC-Cpo-022440	Cavia porcellus	78.48	0.00e+00	2248.00
IUUC-Csa-023391	Chlorocebus sabaeus	82.53	0.00e+00	2381.00
IUUC-Cho-024795	Choloepus hoffmanni	72.45	0.00e+00	1924.00
IUUC-Cin-025137	Ciona intestinalis	34.18	9.00e-32	129.00
IUUC-Dre-027932	Danio rerio	63.92	0.00e+00	851.00
IUUC-Dno-029750	Dasypus novemcinctus	81.88	0.00e+00	2358.00
IUUC-Dor-031109	Dipodomys ordii	74.08	0.00e+00	2009.00
IUUC-Ete-032660	Echinops telfairi	74.76	0.00e+00	1796.00
IUUC-Eca-033433	Equus caballus	84.03	0.00e+00	2336.00
IUUC-Eeu-034929	Erinaceus europaeus	76.11	0.00e+00	1371.00
IUUC-Fca-035859	Felis catus	89.08	0.00e+00	2595.00
IUUC-Fal-036653	Ficedula albicollis	71.07	0.00e+00	1145.00
IUUC-Gmo-038948	Gadus morhua	61.18	0.00e+00	773.00
IUUC-Gga-040279	Gallus gallus	69.86	0.00e+00	1133.00
IUUC-Gac-041641	Gasterosteus aculeatus	56.92	0.00e+00	924.00
IUUC-Hsa-046063	Homo sapiens	82.91	0.00e+00	2382.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	79.00	0.00e+00	2321.00
IUUC-Kpa-049278	Komagataella pastoris	29.46	5.00e-17	83.20
IUUC-Lch-049865	Latimeria chalumnae	48.48	0.00e+00	1137.00
IUUC-Lpe-050758	Leersia perrieri	56.52	5.40e-02	32.70
IUUC-Loc-051754	Lepisosteus oculatus	56.54	0.00e+00	1107.00
IUUC-Laf-054037	Loxodonta africana	80.68	0.00e+00	2399.00
IUUC-Mcc-055002	Macaca mulatta	82.97	0.00e+00	2400.00
IUUC-Meu-056420	Macropus eugenii	62.76	0.00e+00	1352.00
IUUC-Mga-059868	Meleagris gallopavo	71.41	0.00e+00	1125.00
IUUC-Mmr-060767	Microcebus murinus	82.18	0.00e+00	2391.00
IUUC-Mdo-061939	Monodelphis domestica	68.48	0.00e+00	1909.00
IUUC-Mmu-063980	Mus musculus	72.10	0.00e+00	2046.00
IUUC-Mpu-065913	Mustela putorius furo	88.51	0.00e+00	2622.00
IUUC-Mlu-067340	Myotis lucifugus	82.91	0.00e+00	2309.00
IUUC-Nle-069343	Nomascus leucogenys	82.60	0.00e+00	2344.00
IUUC-Opr-070694	Ochotona princeps	74.27	0.00e+00	2086.00
IUUC-Ont-071844	Oreochromis niloticus	58.37	0.00e+00	912.00
IUUC-Oan-073605	Ornithorhynchus anatinus	40.42	7.00e-55	207.00
IUUC-Ocu-074406	Oryctolagus cuniculus	79.65	0.00e+00	2257.00
IUUC-Ola-087343	Oryzias latipes	59.35	0.00e+00	681.00
IUUC-Oga-088847	Otolemur garnettii	82.33	0.00e+00	2338.00
IUUC-Oar-089817	Ovis aries	81.48	0.00e+00	2308.00
IUUC-Pan-092104	Papio anubis	82.79	0.00e+00	2385.00
IUUC-Psi-094045	Pelodiscus sinensis	64.43	2.00e-93	337.00
IUUC-Pma-094663	Petromyzon marinus	44.51	6.00e-133	469.00
IUUC-Pfo-096714	Poecilia formosa	54.93	0.00e+00	919.00
IUUC-Pab-097918	Pongo abelii	82.84	0.00e+00	2362.00
IUUC-Pca-101096	Procavia capensis	74.66	0.00e+00	1239.00
IUUC-Pva-102490	Pteropus vampyrus	81.79	0.00e+00	2389.00
IUUC-Rno-105908	Rattus norvegicus	72.38	0.00e+00	2024.00
IUUC-Sha-107509	Sarcophilus harrisii	67.53	0.00e+00	1784.00
IUUC-Ssc-115250	Sus scrofa	82.17	0.00e+00	2258.00
IUUC-Tru-118279	Takifugu rubripes	56.12	0.00e+00	963.00
IUUC-Tni-120459	Tetraodon nigroviridis	63.31	0.00e+00	744.00
IUUC-Tbe-127753	Tupaia belangeri	65.97	0.00e+00	964.00
IUUC-Ttr-129096	Tursiops truncatus	82.77	0.00e+00	1728.00
IUUC-Vpa-130643	Vicugna pacos	80.85	0.00e+00	1977.00
IUUC-Xtr-131979	Xenopus tropicalis	53.95	0.00e+00	1533.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence