iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000023765.3	ENSMMUT00000064877.1	ENSMMUP00000060061.1
ENSMMUG00000023765.3	ENSMMUT00000063646.1	ENSMMUP00000044018.1
ENSMMUG00000023765.3	ENSMMUT00000056633.1	ENSMMUP00000048116.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.80e-49	164.4	248	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
             +ly ++a + +eL ++ Gd+++++  ++ + gWl+g   l+g+ G+fP  Fv+
   Q: 248  GVALYRFQALEPNELDFEVGDKIRIL--ATLEDGWLEG--SLKGRTGIFPYRFVK 298
           579***********************..999*******..9************97 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEAGSVVRAI FDFCPSVSEE LPLFVGDVIE VLAVVDEFWL LGKKEDVTGQ FPSSFVEIVT 60
IPSLKEGERL FVCICEFTSQ ELDSLPLHRG DLVILDGVPT AGWLQGRSCW GARGFFPSSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCACACGG GATCGACCCG CCCGCCGCTT CCAGGGGCGG AGGTGACAGC GGGCCGGGGA 60
CGGGCGGCTG CAACTGCCTG CCGCGCCGAG GGACCGTCGG GCGGTCGAAA GCAGGTCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

mcc:709334

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	82.81	0.00e+00	2366.00
IUUC-Apl-003934	Anas platyrhynchos	71.54	0.00e+00	1166.00
IUUC-Aca-005005	Anolis carolinensis	62.77	0.00e+00	1227.00
IUUC-Ame-011361	Astyanax mexicanus	60.43	0.00e+00	988.00
IUUC-Bta-013210	Bos taurus	83.71	0.00e+00	2387.00
IUUC-Cel-018396	Caenorhabditis elegans	26.77	1.00e-30	129.00
IUUC-Cja-019104	Callithrix jacchus	92.01	0.00e+00	2637.00
IUUC-Cfa-020960	Canis familiaris	82.97	0.00e+00	2361.00
IUUC-Cpo-022440	Cavia porcellus	80.92	0.00e+00	2340.00
IUUC-Csa-023391	Chlorocebus sabaeus	98.16	0.00e+00	2888.00
IUUC-Cho-024795	Choloepus hoffmanni	74.52	0.00e+00	2019.00
IUUC-Cin-025137	Ciona intestinalis	33.16	1.00e-30	125.00
IUUC-Dre-027932	Danio rerio	57.65	0.00e+00	957.00
IUUC-Dno-029750	Dasypus novemcinctus	82.55	0.00e+00	2449.00
IUUC-Dor-031109	Dipodomys ordii	77.14	0.00e+00	2147.00
IUUC-Ete-032660	Echinops telfairi	74.46	0.00e+00	1807.00
IUUC-Eca-033433	Equus caballus	84.83	0.00e+00	2351.00
IUUC-Eeu-034929	Erinaceus europaeus	76.43	0.00e+00	1377.00
IUUC-Fca-035859	Felis catus	84.80	0.00e+00	2464.00
IUUC-Fal-036653	Ficedula albicollis	72.83	0.00e+00	1161.00
IUUC-Gmo-038948	Gadus morhua	62.69	0.00e+00	795.00
IUUC-Gga-040279	Gallus gallus	71.86	0.00e+00	1142.00
IUUC-Gac-041641	Gasterosteus aculeatus	56.64	0.00e+00	951.00
IUUC-Hsa-046063	Homo sapiens	96.51	0.00e+00	2828.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	82.51	0.00e+00	2449.00
IUUC-Lch-049865	Latimeria chalumnae	48.82	0.00e+00	1164.00
IUUC-Lpe-050758	Leersia perrieri	56.52	5.30e-02	32.70
IUUC-Loc-051754	Lepisosteus oculatus	62.29	0.00e+00	1096.00
IUUC-Laf-054037	Loxodonta africana	83.08	0.00e+00	2488.00
IUUC-Meu-056420	Macropus eugenii	65.06	0.00e+00	1386.00
IUUC-Mga-059868	Meleagris gallopavo	72.28	0.00e+00	1154.00
IUUC-Mmr-060767	Microcebus murinus	86.80	0.00e+00	2547.00
IUUC-Mdo-061939	Monodelphis domestica	69.00	0.00e+00	1926.00
IUUC-Mmu-063980	Mus musculus	75.74	0.00e+00	2182.00
IUUC-Mpu-065913	Mustela putorius furo	82.49	0.00e+00	2419.00
IUUC-Mlu-067340	Myotis lucifugus	83.74	0.00e+00	2341.00
IUUC-Nle-069343	Nomascus leucogenys	96.01	0.00e+00	2781.00
IUUC-Opr-070694	Ochotona princeps	76.91	0.00e+00	2201.00
IUUC-Ont-071844	Oreochromis niloticus	58.10	0.00e+00	932.00
IUUC-Oan-073605	Ornithorhynchus anatinus	42.32	4.00e-64	238.00
IUUC-Ocu-074406	Oryctolagus cuniculus	82.58	0.00e+00	2371.00
IUUC-Ola-087343	Oryzias latipes	59.97	0.00e+00	693.00
IUUC-Oga-088847	Otolemur garnettii	86.73	0.00e+00	2501.00
IUUC-Oar-089817	Ovis aries	81.74	0.00e+00	2328.00
IUUC-Pan-092104	Papio anubis	98.73	0.00e+00	2910.00
IUUC-Psi-094045	Pelodiscus sinensis	64.09	2.00e-92	333.00
IUUC-Pma-094663	Petromyzon marinus	42.04	2.00e-152	533.00
IUUC-Pfo-096714	Poecilia formosa	54.57	0.00e+00	939.00
IUUC-Pab-097918	Pongo abelii	95.88	0.00e+00	2809.00
IUUC-Pca-101096	Procavia capensis	77.63	0.00e+00	1294.00
IUUC-Pva-102490	Pteropus vampyrus	82.83	0.00e+00	2437.00
IUUC-Rno-105908	Rattus norvegicus	75.08	0.00e+00	2107.00
IUUC-Sha-107509	Sarcophilus harrisii	69.46	0.00e+00	1832.00
IUUC-Ssc-115250	Sus scrofa	82.13	0.00e+00	2295.00
IUUC-Tru-118279	Takifugu rubripes	56.30	0.00e+00	979.00
IUUC-Tni-120459	Tetraodon nigroviridis	63.80	0.00e+00	762.00
IUUC-Tbe-127753	Tupaia belangeri	69.72	0.00e+00	1064.00
IUUC-Ttr-129096	Tursiops truncatus	83.38	0.00e+00	1716.00
IUUC-Vpa-130643	Vicugna pacos	80.32	0.00e+00	1979.00
IUUC-Xtr-131979	Xenopus tropicalis	55.70	0.00e+00	1596.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence