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Tag Content
UUCD2 ID IUUC-Mlu-067001
UUCD1 version UUC-MyL-00316
Ensembl Protein ID ENSMLUP00000005761.2
UniProt Accession G1P6Q6; G1P6Q6_MYOLU
Genbank Protein ID ENSMLUP00000005761
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02049066
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000006302.2 ENSMLUT00000006309.2 ENSMLUP00000005761.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.30e-58 191.6 409 443
UBD/Beta-Prp 6.70e-69 232.4 322 487
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 409  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 443
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ 
   Q: 322  TLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR- 405
           4556679*************9..8**************************************..************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 406  VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 487
           ***************9..***********************************99.************..99**************7 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MEDQNEDESP KKNTLWQISN GTSSVIVSRK RPSEGNYQKE KDLCIKYFDQ WSESDQVEFV 60
EHLISRMCHY QHGHINSYLK PMLQRDFITA LPEQGLDHIA ENILSYLDAR SLCAAELVCK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067001|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAGGATC AAAATGAAGA TGAGTCCCCC AAGAAAAATA CTCTTTGGCA GGTAGGAATG 60
ACTGCGCACA GATCAGAGAG CAGTTGACTC ACTCTAGACA AGATGCCCCT CAGCTCATGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067001|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 100.00 0.00e+00 1021.00
IUUC-Apl-003449 Anas platyrhynchos 99.41 0.00e+00 1048.00
IUUC-Aca-004341 Anolis carolinensis 99.10 0.00e+00 912.00
IUUC-Ang-009766 Aspergillus niger 31.41 5.00e-52 199.00
IUUC-Ame-011393 Astyanax mexicanus 90.20 0.00e+00 954.00
IUUC-Bta-012920 Bos taurus 99.80 0.00e+00 1055.00
IUUC-Cel-018392 Caenorhabditis elegans 63.16 0.00e+00 634.00
IUUC-Cja-018879 Callithrix jacchus 100.00 0.00e+00 1021.00
IUUC-Cfa-020021 Canis familiaris 100.00 0.00e+00 1021.00
IUUC-Cpo-022151 Cavia porcellus 99.61 0.00e+00 1048.00
IUUC-Csa-024095 Chlorocebus sabaeus 100.00 0.00e+00 1056.00
IUUC-Cho-024658 Choloepus hoffmanni 99.53 1.00e-126 446.00
IUUC-Cin-025188 Ciona intestinalis 80.42 0.00e+00 823.00
IUUC-Dre-028160 Danio rerio 90.12 0.00e+00 956.00
IUUC-Dno-029485 Dasypus novemcinctus 89.30 0.00e+00 925.00
IUUC-Dor-030498 Dipodomys ordii 99.60 0.00e+00 1015.00
IUUC-Dse-031287 Dothistroma septosporum 28.95 2.00e-52 200.00
IUUC-Eca-033804 Equus caballus 100.00 0.00e+00 1021.00
IUUC-Fca-035887 Felis catus 100.00 0.00e+00 1057.00
IUUC-Fal-036783 Ficedula albicollis 99.61 0.00e+00 1053.00
IUUC-Gmo-038590 Gadus morhua 91.30 0.00e+00 929.00
IUUC-Gga-040628 Gallus gallus 99.22 0.00e+00 1048.00
IUUC-Gac-041305 Gasterosteus aculeatus 90.89 0.00e+00 931.00
IUUC-Ggo-044604 Gorilla gorilla 100.00 0.00e+00 1021.00
IUUC-Hsa-046139 Homo sapiens 100.00 0.00e+00 1021.00
IUUC-Lch-050460 Latimeria chalumnae 96.86 0.00e+00 1027.00
IUUC-Laf-053968 Loxodonta africana 100.00 0.00e+00 1057.00
IUUC-Mcc-055822 Macaca mulatta 96.76 0.00e+00 1044.00
IUUC-Mga-059225 Meleagris gallopavo 99.02 0.00e+00 1041.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 2.00e-69 257.00
IUUC-Mmr-060746 Microcebus murinus 100.00 0.00e+00 1021.00
IUUC-Mdo-062005 Monodelphis domestica 99.41 0.00e+00 1051.00
IUUC-Mmu-063851 Mus musculus 99.22 0.00e+00 1050.00
IUUC-Mpu-065716 Mustela putorius furo 100.00 0.00e+00 1056.00
IUUC-Nle-069788 Nomascus leucogenys 100.00 0.00e+00 1020.00
IUUC-Opr-071229 Ochotona princeps 99.80 0.00e+00 1020.00
IUUC-Ont-071792 Oreochromis niloticus 91.50 0.00e+00 939.00
IUUC-Oan-072782 Ornithorhynchus anatinus 99.61 0.00e+00 1053.00
IUUC-Ocu-074894 Oryctolagus cuniculus 100.00 0.00e+00 1057.00
IUUC-Ola-086985 Oryzias latipes 90.23 0.00e+00 956.00
IUUC-Oga-088604 Otolemur garnettii 94.10 0.00e+00 1039.00
IUUC-Oar-090412 Ovis aries 100.00 0.00e+00 1057.00
IUUC-Ptr-091039 Pan troglodytes 99.80 0.00e+00 1020.00
IUUC-Pan-092770 Papio anubis 100.00 0.00e+00 1009.00
IUUC-Psi-093887 Pelodiscus sinensis 98.82 0.00e+00 1043.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 2.00e-45 177.00
IUUC-Pfo-096783 Poecilia formosa 90.62 0.00e+00 958.00
IUUC-Pva-102547 Pteropus vampyrus 99.80 0.00e+00 1015.00
IUUC-Ptt-103853 Puccinia triticina 32.75 3.00e-60 226.00
IUUC-Rno-105246 Rattus norvegicus 99.22 0.00e+00 1050.00
IUUC-Sha-107339 Sarcophilus harrisii 99.41 0.00e+00 1051.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.38 4.00e-74 271.00
IUUC-Spo-108200 Schizosaccharomyces pombe 32.42 3.00e-66 246.00
IUUC-Tgu-116541 Taeniopygia guttata 99.41 0.00e+00 1049.00
IUUC-Tru-117671 Takifugu rubripes 89.65 0.00e+00 949.00
IUUC-Tni-120359 Tetraodon nigroviridis 90.04 0.00e+00 946.00
IUUC-Tbe-127418 Tupaia belangeri 93.32 0.00e+00 936.00
IUUC-Ttr-129131 Tursiops truncatus 100.00 0.00e+00 1021.00
IUUC-Vpa-130668 Vicugna pacos 100.00 0.00e+00 1021.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 8.00e-158 548.00
Created Date 25-Jun-2017

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