iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069041

Ensembl Protein ID

ENSNLEP00000008358.1

UniProt Accession

G1R586; G1R586_NOMLE

Genbank Protein ID

ENSNLEP00000008358

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

ADFV01007421

Gene Name

YES1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000006863.2	ENSNLET00000008751.2	ENSNLEP00000008358.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.30e-15	54.5	96	151

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++++L++kkG+  ++i  ++++++W+++ + ++gk+G +P+n+v+ ++
   Q: 96   FVALYDYEARTTEDLSFKKGERFQII--NNTEGDWWEARSIATGKNGYIPSNYVAPAD 151
           789***********************..8999**********************9875 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MGCIKSKENK SPAIKYRPEN TPEPVSTSVS HYGAEPTTVS PCPSSSAKGT AVNFSSLSMT 60
PFGGSSGVTP FGGASSSFSV VPSSYPAGLT GGVTIFVALY DYEARTTEDL SFKKGERFQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGCA TTAAAAGTAA AGAAAACAAA AGTCCAGCCA TTAAATACAG ACCTGAAAAT 60
ACTCCAGAGC CTGTCAGTAC AAGTGTGAGC CATTATGGAG CAGAACCCAC TACAGTGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	93.38	0.00e+00	997.00
IUUC-Apl-004032	Anas platyrhynchos	88.21	0.00e+00	955.00
IUUC-Aca-004255	Anolis carolinensis	86.56	0.00e+00	962.00
IUUC-Ame-010954	Astyanax mexicanus	81.72	0.00e+00	917.00
IUUC-Bta-013503	Bos taurus	92.82	0.00e+00	971.00
IUUC-Cja-019694	Callithrix jacchus	94.29	0.00e+00	987.00
IUUC-Cfa-020402	Canis familiaris	93.55	0.00e+00	1001.00
IUUC-Cpo-022506	Cavia porcellus	92.27	0.00e+00	988.00
IUUC-Csa-023713	Chlorocebus sabaeus	95.58	0.00e+00	1003.00
IUUC-Dre-027978	Danio rerio	80.59	0.00e+00	880.00
IUUC-Dno-029897	Dasypus novemcinctus	91.63	0.00e+00	870.00
IUUC-Dor-030202	Dipodomys ordii	92.92	0.00e+00	871.00
IUUC-Eca-034157	Equus caballus	93.92	0.00e+00	1005.00
IUUC-Eeu-034950	Erinaceus europaeus	92.09	7.00e-179	619.00
IUUC-Fca-036233	Felis catus	93.19	0.00e+00	1020.00
IUUC-Fal-037461	Ficedula albicollis	88.21	0.00e+00	974.00
IUUC-Gmo-038929	Gadus morhua	78.69	0.00e+00	853.00
IUUC-Gga-041107	Gallus gallus	87.85	0.00e+00	956.00
IUUC-Gac-042321	Gasterosteus aculeatus	79.96	0.00e+00	887.00
IUUC-Ggo-044597	Gorilla gorilla	78.21	0.00e+00	808.00
IUUC-Hsa-047010	Homo sapiens	95.58	0.00e+00	1031.00
IUUC-Lch-050239	Latimeria chalumnae	85.45	0.00e+00	951.00
IUUC-Loc-052314	Lepisosteus oculatus	83.73	0.00e+00	885.00
IUUC-Laf-053517	Loxodonta africana	93.00	0.00e+00	975.00
IUUC-Mcc-055626	Macaca mulatta	95.58	0.00e+00	1002.00
IUUC-Mga-059310	Meleagris gallopavo	87.85	0.00e+00	956.00
IUUC-Mmr-061652	Microcebus murinus	93.00	0.00e+00	998.00
IUUC-Mdo-062963	Monodelphis domestica	87.48	0.00e+00	966.00
IUUC-Mmu-064128	Mus musculus	91.90	0.00e+00	1005.00
IUUC-Mpu-065906	Mustela putorius furo	93.74	0.00e+00	1004.00
IUUC-Mlu-067035	Myotis lucifugus	93.04	0.00e+00	995.00
IUUC-Opr-070299	Ochotona princeps	83.06	0.00e+00	868.00
IUUC-Ont-072337	Oreochromis niloticus	81.35	0.00e+00	905.00
IUUC-Oan-072997	Ornithorhynchus anatinus	92.53	0.00e+00	873.00
IUUC-Ocu-074171	Oryctolagus cuniculus	93.00	0.00e+00	1002.00
IUUC-Ola-086619	Oryzias latipes	80.40	0.00e+00	903.00
IUUC-Oga-087957	Otolemur garnettii	92.27	0.00e+00	983.00
IUUC-Oar-089670	Ovis aries	89.87	0.00e+00	966.00
IUUC-Ptr-091352	Pan troglodytes	95.58	0.00e+00	1029.00
IUUC-Pan-092202	Papio anubis	95.58	0.00e+00	1002.00
IUUC-Psi-093310	Pelodiscus sinensis	87.29	0.00e+00	964.00
IUUC-Pfo-096137	Poecilia formosa	79.57	0.00e+00	877.00
IUUC-Pab-098301	Pongo abelii	95.26	0.00e+00	912.00
IUUC-Pva-102592	Pteropus vampyrus	92.63	0.00e+00	976.00
IUUC-Rno-105544	Rattus norvegicus	91.53	0.00e+00	969.00
IUUC-Sar-113364	Sorex araneus	88.95	0.00e+00	920.00
IUUC-Tgu-117380	Taeniopygia guttata	88.21	0.00e+00	974.00
IUUC-Tru-117594	Takifugu rubripes	80.58	0.00e+00	889.00
IUUC-Tni-120433	Tetraodon nigroviridis	80.65	0.00e+00	882.00
IUUC-Ttr-128893	Tursiops truncatus	93.37	0.00e+00	1003.00
IUUC-Vpa-130060	Vicugna pacos	93.74	0.00e+00	991.00
IUUC-Xtr-132322	Xenopus tropicalis	86.00	0.00e+00	947.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence