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Tag Content
UUCD2 ID IUUC-Itr-047895
UUCD1 version UUC-SpT-00190
Ensembl Protein ID ENSSTOP00000003148.2
UniProt Accession I3M2E9; I3M2E9_ICTTR
Genbank Protein ID ENSSTOP00000003148
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTP01085324
Gene Name RNF41
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000003519.2 ENSSTOT00000003516.2 ENSSTOP00000003148.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.00e-06 27.6 18 57
E3 activity/RING/U-box 1.10e-06 28.6 12 69
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC   +++ p+  p C H+f+  C+ +w       s++++CP++r
   Q: 18   CPICSGVLEE-PVQAPhCEHAFCNACITQW------FSQQQTCPVDR 57
           ****999999.777777*************......********987 PP
   

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnl 59
           v e+++CpI   + ++Pv +p + + +  ++I +w++++++ cPv+r+ +t   l P  
   Q: 12   VDEDLICPICSGVLEEPVQAPhCEHAFCNACITQWFSQQQT-CPVDRSVVTVAHLRPVP 69
           56899******************************998887.******99998887764 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MGYDVTRFQG DVDEDLICPI CSGVLEEPVQ APHCEHAFCN ACITQWFSQQ QTCPVDRSVV 60
TVAHLRPVPR IMRNMLSKLQ IACDNAVFGC SAVVRLDNLM SHLSDCEHNP KRPVTCEQGC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-047895|E3,RING;E3,U-box|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGATTGTGA CATTACATTC ATCCGTTGGT GATGGAGTTT GTCACTAGGA AGGAAGACTC 60
AATTGGAGAA TAGCCAACAA GATGGGTTAC TTGGAGCATC TCCTGAGTGG TACTGAGTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-047895|E3,RING;E3,U-box|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR008974--TRAF-like
IPR015036--USP8_interacting
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR013010--Znf_SIAH
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS51081--ZF_SIAH
Pfam

PF08941--USP8_interact
SMART

SM00184--RING
Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0031386--F:protein tag
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0030336--P:negative regulation of cell migration
GO:0008285--P:negative regulation of cell proliferation
GO:1901525--P:negative regulation of macromitophagy
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0010498--P:proteasomal protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:2000114--P:regulation of establishment of cell polarity
GO:0045619--P:regulation of lymphocyte differentiation
GO:0043408--P:regulation of MAPK cascade
GO:0045637--P:regulation of myeloid cell differentiation
GO:0051896--P:regulation of protein kinase B signaling
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002398 Ailuropoda melanoleuca 99.68 0.00e+00 659.00
IUUC-Apl-003568 Anas platyrhynchos 96.23 0.00e+00 633.00
IUUC-Aca-005119 Anolis carolinensis 96.85 0.00e+00 645.00
IUUC-Ame-010708 Astyanax mexicanus 91.17 3.00e-179 620.00
IUUC-Bta-013428 Bos taurus 93.69 6.00e-179 619.00
IUUC-Cja-019844 Callithrix jacchus 99.69 0.00e+00 655.00
IUUC-Cfa-021124 Canis familiaris 100.00 0.00e+00 660.00
IUUC-Cpo-022325 Cavia porcellus 99.68 0.00e+00 659.00
IUUC-Csa-023113 Chlorocebus sabaeus 100.00 0.00e+00 660.00
IUUC-Cho-024991 Choloepus hoffmanni 99.48 2.00e-114 404.00
IUUC-Cne-026870 Cryptococcus neoformans 38.52 4.00e-20 93.20
IUUC-Dre-028730 Danio rerio 90.85 7.00e-179 619.00
IUUC-Dno-028908 Dasypus novemcinctus 99.65 4.00e-172 596.00
IUUC-Dor-030411 Dipodomys ordii 99.68 0.00e+00 660.00
IUUC-Dme-031868 Drosophila melanogaster 57.46 6.00e-111 393.00
IUUC-Ete-032896 Echinops telfairi 81.51 3.00e-125 440.00
IUUC-Eca-034135 Equus caballus 100.00 0.00e+00 660.00
IUUC-Eeu-034675 Erinaceus europaeus 99.68 0.00e+00 659.00
IUUC-Fca-035612 Felis catus 100.00 0.00e+00 660.00
IUUC-Fal-036922 Ficedula albicollis 98.77 9.00e-43 163.00
IUUC-Gmo-039648 Gadus morhua 87.70 2.00e-172 597.00
IUUC-Gga-040474 Gallus gallus 97.16 0.00e+00 646.00
IUUC-Gac-041951 Gasterosteus aculeatus 88.96 2.00e-175 607.00
IUUC-Ggo-045126 Gorilla gorilla 99.69 0.00e+00 655.00
IUUC-Hsa-046402 Homo sapiens 100.00 0.00e+00 660.00
IUUC-Lch-050266 Latimeria chalumnae 93.69 0.00e+00 630.00
IUUC-Loc-052547 Lepisosteus oculatus 92.11 4.00e-180 623.00
IUUC-Laf-054332 Loxodonta africana 99.37 0.00e+00 655.00
IUUC-Mcc-055869 Macaca mulatta 100.00 0.00e+00 660.00
IUUC-Meu-056735 Macropus eugenii 100.00 2.00e-172 597.00
IUUC-Mla-059147 Melampsora laricipopulina 37.11 4.00e-13 68.90
IUUC-Mga-060100 Meleagris gallopavo 97.16 0.00e+00 646.00
IUUC-Mmr-061382 Microcebus murinus 100.00 0.00e+00 660.00
IUUC-Mmu-064225 Mus musculus 99.68 0.00e+00 659.00
IUUC-Mpu-066709 Mustela putorius furo 100.00 0.00e+00 660.00
IUUC-Mlu-067168 Myotis lucifugus 99.05 0.00e+00 658.00
IUUC-Nle-070176 Nomascus leucogenys 100.00 0.00e+00 660.00
IUUC-Opr-070259 Ochotona princeps 99.68 0.00e+00 659.00
IUUC-Ont-071235 Oreochromis niloticus 90.22 1.00e-177 614.00
IUUC-Oan-072850 Ornithorhynchus anatinus 96.05 7.00e-84 303.00
IUUC-Ocu-074165 Oryctolagus cuniculus 99.68 0.00e+00 659.00
IUUC-Ola-086658 Oryzias latipes 88.64 1.00e-173 601.00
IUUC-Oga-088933 Otolemur garnettii 100.00 0.00e+00 660.00
IUUC-Oar-090089 Ovis aries 99.68 0.00e+00 660.00
IUUC-Ptr-091263 Pan troglodytes 100.00 0.00e+00 660.00
IUUC-Pan-092926 Papio anubis 100.00 0.00e+00 660.00
IUUC-Psi-093934 Pelodiscus sinensis 89.62 1.00e-168 585.00
IUUC-Pma-094578 Petromyzon marinus 68.97 4.00e-127 447.00
IUUC-Pno-094854 Phaeosphaeria nodorum 36.59 1.00e-13 70.90
IUUC-Pfo-097431 Poecilia formosa 90.22 3.00e-177 613.00
IUUC-Pab-097852 Pongo abelii 100.00 0.00e+00 660.00
IUUC-Pca-100496 Procavia capensis 91.51 4.00e-169 586.00
IUUC-Pva-103157 Pteropus vampyrus 99.00 7.00e-117 412.00
IUUC-Pgr-103416 Puccinia graminis 32.04 2.00e-13 70.50
IUUC-Pyt-104429 Pyrenophora triticirepentis 37.61 1.00e-12 67.80
IUUC-Rno-105928 Rattus norvegicus 99.68 0.00e+00 659.00
IUUC-Sha-107556 Sarcophilus harrisii 99.37 0.00e+00 654.00
IUUC-Sar-113208 Sorex araneus 100.00 0.00e+00 660.00
IUUC-Ssc-116011 Sus scrofa 99.68 0.00e+00 660.00
IUUC-Tgu-116882 Taeniopygia guttata 75.00 1.00e-73 268.00
IUUC-Tru-117987 Takifugu rubripes 89.91 6.00e-177 612.00
IUUC-Tsy-118785 Tarsius syrichta 99.68 0.00e+00 654.00
IUUC-Tni-120165 Tetraodon nigroviridis 89.59 2.00e-176 611.00
IUUC-Tbe-127920 Tupaia belangeri 99.50 7.00e-119 418.00
IUUC-Ttr-129160 Tursiops truncatus 99.37 0.00e+00 659.00
IUUC-Vpa-130629 Vicugna pacos 100.00 0.00e+00 660.00
IUUC-Xtr-131895 Xenopus tropicalis 95.27 0.00e+00 636.00
Created Date 25-Jun-2017

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