iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020403

Ensembl Protein ID

ENSCAFP00000030928.2

UniProt Accession

E2QX80; E2QX80_CANLF

Genbank Protein ID

ENSCAFP00000030928

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03001403

Gene Name

RNF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006241.3	ENSCAFT00000035645.2	ENSCAFP00000030928.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	9.50e-56	189.4	220	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e++++leC+h++Ck+Clk+y+e++i++gqv++++cp+++cp+ +++ ++ke lv++el++ry++lll+++++ +a++ +
   Q: 220  CNICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKE-LVDTELFARYDRLLLQSTLDLMADVVY 308
           **************************************************************.7************************** PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+p+C+l+v++e+     ++  c++c+++fC+ C+ ++H  + Ck ++ekl++ ++e+                        ee+eske
   Q: 309  CPRPCCQLPVMQEPG---CTMGiCSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYlqadeankrfleqrygkrviqkalEEMESKE 395
           *************95...33337**********************************99******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C ++iek +gCn+mtC+ C+++fCw+C
   Q: 396  WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWIC 433
           ************************************** PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSSEDREAQE DELLALASIY DGDEFRKAES VQGGETRIYL DLPQNFKIFV SGNSNECLQN 60
GGFEYTICFL PPLVLNFELP PDYPSSSPPS FTLSGKWLSP TQLSALCKHL DNLWEEHRGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGAGCCCC GGGGGCACAG AAGCTGCGTT TGTATCAACT TGCCAGGGCC GCGTGTGGGG 60
CGCGGTGACG GGACCGCGCC GGCAGCGCCG CCTTTGGCCT GCAGGGGGCG ACCGAGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0007165--P:signal transduction

KEGG

cfa:478042

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	29.85	1.00e-50	194.00
IUUC-Aml-001458	Ailuropoda melanoleuca	98.53	0.00e+00	937.00
IUUC-Atr-002560	Amborella trichopoda	30.94	1.00e-45	178.00
IUUC-Apl-003680	Anas platyrhynchos	82.70	0.00e+00	780.00
IUUC-Aca-005000	Anolis carolinensis	71.64	0.00e+00	667.00
IUUC-Aly-006288	Arabidopsis lyrata	31.25	3.00e-54	206.00
IUUC-Ath-006719	Arabidopsis thaliana	31.17	7.00e-54	205.00
IUUC-Acl-008213	Aspergillus clavatus	24.84	8.00e-30	125.00
IUUC-Afl-008433	Aspergillus flavus	24.34	1.00e-30	128.00
IUUC-Afu-008772	Aspergillus fumigatus	25.00	1.00e-32	135.00
IUUC-Ani-009249	Aspergillus nidulans	25.42	3.00e-32	133.00
IUUC-Ang-009757	Aspergillus niger	27.75	3.00e-36	146.00
IUUC-Aor-009963	Aspergillus oryzae	24.34	3.00e-30	127.00
IUUC-Ate-010460	Aspergillus terreus	25.11	2.00e-31	130.00
IUUC-Ame-011312	Astyanax mexicanus	58.61	4.00e-145	507.00
IUUC-Bgr-012052	Blumeria graminis	23.11	3.00e-29	123.00
IUUC-Bta-013529	Bos taurus	97.26	0.00e+00	930.00
IUUC-Bci-013729	Botrytis cinerea	24.29	3.00e-26	113.00
IUUC-Bdi-014940	Brachypodium distachyon	31.82	7.00e-49	188.00
IUUC-Bra-016998	Brassica rapa	29.91	3.00e-50	193.00
IUUC-Cel-018547	Caenorhabditis elegans	30.75	4.00e-51	195.00
IUUC-Cja-019791	Callithrix jacchus	94.73	0.00e+00	911.00
IUUC-Cpo-022229	Cavia porcellus	90.97	0.00e+00	863.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	33.95	4.00e-29	120.00
IUUC-Csa-024115	Chlorocebus sabaeus	95.99	0.00e+00	920.00
IUUC-Cho-024911	Choloepus hoffmanni	97.47	0.00e+00	931.00
IUUC-Cin-025578	Ciona intestinalis	42.13	1.00e-97	350.00
IUUC-Csv-026355	Ciona savignyi	41.05	4.00e-85	308.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	22.85	3.00e-24	107.00
IUUC-Cne-026782	Cryptococcus neoformans	25.07	7.00e-30	125.00
IUUC-Dre-027380	Danio rerio	57.33	2.00e-154	538.00
IUUC-Dno-029640	Dasypus novemcinctus	96.84	0.00e+00	922.00
IUUC-Dor-030681	Dipodomys ordii	95.57	0.00e+00	916.00
IUUC-Dse-031208	Dothistroma septosporum	23.81	9.00e-30	125.00
IUUC-Ete-033122	Echinops telfairi	60.53	3.00e-133	468.00
IUUC-Eca-033755	Equus caballus	95.50	0.00e+00	899.00
IUUC-Eeu-035034	Erinaceus europaeus	97.26	2.00e-72	266.00
IUUC-Fca-036461	Felis catus	97.68	0.00e+00	934.00
IUUC-Fal-037516	Ficedula albicollis	81.05	0.00e+00	773.00
IUUC-Fso-038307	Fusarium solani	24.84	2.00e-24	107.00
IUUC-Gmo-039563	Gadus morhua	57.93	5.00e-149	520.00
IUUC-Ggr-039920	Gaeumannomyces graminis	25.24	2.00e-23	104.00
IUUC-Gga-040331	Gallus gallus	81.74	0.00e+00	764.00
IUUC-Gac-042164	Gasterosteus aculeatus	59.45	2.00e-160	558.00
IUUC-Gma-044080	Glycine max	31.96	3.00e-58	219.00
IUUC-Ggo-045257	Gorilla gorilla	95.57	0.00e+00	919.00
IUUC-Hsa-046887	Homo sapiens	96.30	0.00e+00	896.00
IUUC-Hvu-047317	Hordeum vulgare	29.55	4.00e-48	185.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	96.41	0.00e+00	926.00
IUUC-Lch-050155	Latimeria chalumnae	63.73	3.00e-164	571.00
IUUC-Lpe-051669	Leersia perrieri	30.65	7.00e-39	155.00
IUUC-Loc-051779	Lepisosteus oculatus	59.59	8.00e-154	536.00
IUUC-Lma-052969	Leptosphaeria maculans	23.86	2.00e-29	123.00
IUUC-Laf-053488	Loxodonta africana	93.25	0.00e+00	893.00
IUUC-Mcc-054701	Macaca mulatta	96.74	0.00e+00	899.00
IUUC-Meu-056577	Macropus eugenii	83.27	4.00e-127	447.00
IUUC-Mor-057157	Magnaporthe oryzae	22.57	6.00e-27	115.00
IUUC-Mpo-057518	Magnaporthe poae	23.49	3.00e-27	117.00
IUUC-Mtr-058125	Medicago truncatula	30.18	1.00e-46	181.00
IUUC-Mga-059906	Meleagris gallopavo	81.74	0.00e+00	761.00
IUUC-Mvi-060374	Microbotryum violaceum	32.17	9.00e-34	138.00
IUUC-Mmr-061786	Microcebus murinus	97.89	0.00e+00	934.00
IUUC-Mdo-062453	Monodelphis domestica	90.57	0.00e+00	835.00
IUUC-Mmu-063521	Mus musculus	91.15	0.00e+00	823.00
IUUC-Mac-065119	Musa acuminata	29.93	6.00e-40	158.00
IUUC-Mpu-066274	Mustela putorius furo	98.31	0.00e+00	941.00
IUUC-Mlu-067202	Myotis lucifugus	92.39	0.00e+00	846.00
IUUC-Nfi-068564	Neosartorya fischeri	25.00	1.00e-31	131.00
IUUC-Ncr-068823	Neurospora crassa	23.89	1.00e-29	125.00
IUUC-Nle-068987	Nomascus leucogenys	96.53	0.00e+00	900.00
IUUC-Opr-070453	Ochotona princeps	92.83	0.00e+00	888.00
IUUC-Ont-072611	Oreochromis niloticus	57.98	7.00e-158	550.00
IUUC-Oan-073738	Ornithorhynchus anatinus	82.61	0.00e+00	751.00
IUUC-Ocu-074396	Oryctolagus cuniculus	95.15	0.00e+00	910.00
IUUC-Oba-075472	Oryza barthii	31.87	4.00e-43	169.00
IUUC-Obr-076277	Oryza brachyantha	31.15	2.00e-45	177.00
IUUC-Ogl-077046	Oryza glaberrima	31.56	8.00e-42	165.00
IUUC-Ogu-078634	Oryza glumaepatula	31.87	2.00e-43	170.00
IUUC-Oin-080080	Oryza indica	29.58	4.00e-44	172.00
IUUC-Olo-080828	Oryza longistaminata	29.00	2.00e-41	164.00
IUUC-Ome-081387	Oryza meridionalis	29.57	9.00e-47	181.00
IUUC-Oni-082934	Oryza nivara	31.87	2.00e-43	170.00
IUUC-Opu-083719	Oryza punctata	29.04	2.00e-41	163.00
IUUC-Oru-084518	Oryza rufipogon	31.87	2.00e-43	170.00
IUUC-Ola-087312	Oryzias latipes	58.88	2.00e-157	548.00
IUUC-Olu-087661	Ostreococcus lucimarinus	29.03	1.00e-47	184.00
IUUC-Oga-089129	Otolemur garnettii	97.25	0.00e+00	929.00
IUUC-Oar-089839	Ovis aries	97.05	0.00e+00	929.00
IUUC-Ptr-091626	Pan troglodytes	96.52	0.00e+00	898.00
IUUC-Pan-092798	Papio anubis	96.74	0.00e+00	899.00
IUUC-Psi-093253	Pelodiscus sinensis	81.82	0.00e+00	787.00
IUUC-Pma-094512	Petromyzon marinus	55.17	2.00e-144	505.00
IUUC-Pno-094937	Phaeosphaeria nodorum	23.25	1.00e-27	117.00
IUUC-Ppa-095211	Physcomitrella patens	30.50	6.00e-54	205.00
IUUC-Pfo-097049	Poecilia formosa	53.67	1.00e-138	486.00
IUUC-Pab-097911	Pongo abelii	96.30	0.00e+00	897.00
IUUC-Pop-099841	Populus trichocarpa	30.55	4.00e-49	189.00
IUUC-Pca-100814	Procavia capensis	74.62	0.00e+00	668.00
IUUC-Ppe-101972	Prunus persica	31.93	8.00e-51	194.00
IUUC-Pva-103038	Pteropus vampyrus	96.20	0.00e+00	920.00
IUUC-Pgr-103277	Puccinia graminis	32.70	5.00e-39	155.00
IUUC-Ptt-103855	Puccinia triticina	30.37	5.00e-35	142.00
IUUC-Pte-104113	Pyrenophora teres	23.25	2.00e-26	113.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	25.61	7.00e-28	118.00
IUUC-Rno-106003	Rattus norvegicus	91.77	0.00e+00	841.00
IUUC-Sce-106287	Saccharomyces cerevisiae	28.29	1.00e-24	107.00
IUUC-Sha-106652	Sarcophilus harrisii	90.24	0.00e+00	843.00
IUUC-Spo-108167	Schizosaccharomyces pombe	30.25	5.00e-51	194.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	25.00	8.00e-10	59.30
IUUC-Smo-109393	Selaginella moellendorffii	30.82	4.00e-48	186.00
IUUC-Sit-110529	Setaria italica	33.76	4.00e-42	166.00
IUUC-Sly-111829	Solanum lycopersicum	30.60	9.00e-52	198.00
IUUC-Stu-112811	Solanum tuberosum	31.26	9.00e-53	201.00
IUUC-Sar-113259	Sorex araneus	91.01	2.00e-139	488.00
IUUC-Sbi-114591	Sorghum bicolor	31.88	2.00e-35	144.00
IUUC-Sre-115227	Sporisorium reilianum	28.01	3.00e-36	147.00
IUUC-Ssc-115293	Sus scrofa	95.15	0.00e+00	913.00
IUUC-Tgu-117335	Taeniopygia guttata	82.20	0.00e+00	772.00
IUUC-Tru-118458	Takifugu rubripes	57.42	1.00e-154	539.00
IUUC-Tsy-119475	Tarsius syrichta	88.40	0.00e+00	820.00
IUUC-Tni-119827	Tetraodon nigroviridis	57.32	4.00e-153	534.00
IUUC-Tca-121023	Theobroma cacao	32.24	6.00e-52	199.00
IUUC-Tre-121965	Trichoderma reesei	23.48	1.00e-29	124.00
IUUC-Tvi-122564	Trichoderma virens	21.32	4.00e-26	113.00
IUUC-Tae-124793	Triticum aestivum	33.19	1.00e-39	157.00
IUUC-Tur-126258	Triticum urartu	30.47	9.00e-45	174.00
IUUC-Tbe-127227	Tupaia belangeri	75.00	6.00e-80	291.00
IUUC-Ttr-128984	Tursiops truncatus	73.63	0.00e+00	637.00
IUUC-Uma-129565	Ustilago maydis	27.36	1.00e-33	138.00
IUUC-Vpa-130301	Vicugna pacos	97.89	0.00e+00	937.00
IUUC-Vvi-131244	Vitis vinifera	31.33	1.00e-52	201.00
IUUC-Xtr-132880	Xenopus tropicalis	60.59	1.00e-166	579.00
IUUC-Xma-134055	Xiphophorus maculatus	59.66	3.00e-159	555.00
IUUC-Yli-134342	Yarrowia lipolytica	29.74	1.00e-43	170.00
IUUC-Zma-135021	Zea mays	32.78	4.00e-38	152.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence