iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011020

Ensembl Protein ID

ENSAMXP00000026285.1

UniProt Accession

W5LT74; W5LT74_ASTMX

Genbank Protein ID

ENSAMXP00000026285

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01040104

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000025580.1	ENSAMXT00000026306.1	ENSAMXP00000026285.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-19	70.5	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.80e-07	28.8	146	176

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaa+S++F+a+f+++l+es   + v+++d v pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRSFPCHRAVLAACSRYFEAMFSGGLRESL-DSDVNFRDsVHPEVLELLLDFAYSSRVIINE 114
           7************************************9.*******99******************9987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclg++ ++d+++c +L++   +++l hF
   Q: 146  SSNCLGMMLLSDAHQCKRLYELSWRMCLVHF 176
           69****************************9 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MSVSVHENRK SRTSTGSMNI SLFHKPSHPD SVLTHLNTLR KQCMFTDVTL WAGDRSFPCH 60
RAVLAACSRY FEAMFSGGLR ESLDSDVNFR DSVHPEVLEL LLDFAYSSRV IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTCA GCGTCCATGA GAACCGCAAG TCAAGGACAA GCACAGGCTC CATGAACATC 60
TCCCTCTTCC ACAAGCCCTC ACATCCGGAC AGCGTCCTGA CGCACCTCAA CACTCTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	85.57	0.00e+00	1080.00
IUUC-Apl-003543	Anas platyrhynchos	86.95	0.00e+00	1058.00
IUUC-Aca-004729	Anolis carolinensis	84.04	0.00e+00	1040.00
IUUC-Bta-012955	Bos taurus	84.38	0.00e+00	1068.00
IUUC-Cja-018839	Callithrix jacchus	84.72	0.00e+00	1070.00
IUUC-Cfa-020224	Canis familiaris	85.57	0.00e+00	1078.00
IUUC-Cpo-021593	Cavia porcellus	84.04	0.00e+00	1018.00
IUUC-Csa-023276	Chlorocebus sabaeus	85.23	0.00e+00	1076.00
IUUC-Dre-028053	Danio rerio	97.45	0.00e+00	1130.00
IUUC-Dno-029287	Dasypus novemcinctus	83.87	0.00e+00	1056.00
IUUC-Fca-035897	Felis catus	85.91	0.00e+00	1081.00
IUUC-Fal-037036	Ficedula albicollis	87.44	0.00e+00	1070.00
IUUC-Gmo-039345	Gadus morhua	92.87	0.00e+00	1077.00
IUUC-Gga-040404	Gallus gallus	87.10	0.00e+00	1068.00
IUUC-Gac-042447	Gasterosteus aculeatus	93.72	0.00e+00	1100.00
IUUC-Ggo-045060	Gorilla gorilla	85.23	0.00e+00	1076.00
IUUC-Hsa-046494	Homo sapiens	85.23	0.00e+00	1075.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	85.57	0.00e+00	1076.00
IUUC-Lch-050211	Latimeria chalumnae	90.99	0.00e+00	1099.00
IUUC-Loc-052578	Lepisosteus oculatus	95.93	0.00e+00	1145.00
IUUC-Laf-053498	Loxodonta africana	84.55	0.00e+00	1025.00
IUUC-Mcc-055033	Macaca mulatta	85.23	0.00e+00	1077.00
IUUC-Meu-056893	Macropus eugenii	87.10	0.00e+00	1094.00
IUUC-Mga-060025	Meleagris gallopavo	87.27	0.00e+00	1068.00
IUUC-Mmr-060658	Microcebus murinus	85.23	0.00e+00	1077.00
IUUC-Mdo-062667	Monodelphis domestica	87.27	0.00e+00	1093.00
IUUC-Mmu-063125	Mus musculus	83.70	0.00e+00	1024.00
IUUC-Mpu-066209	Mustela putorius furo	85.40	0.00e+00	1078.00
IUUC-Mlu-068237	Myotis lucifugus	83.87	0.00e+00	1035.00
IUUC-Nle-069454	Nomascus leucogenys	85.08	0.00e+00	1061.00
IUUC-Ont-072138	Oreochromis niloticus	94.06	0.00e+00	1091.00
IUUC-Oan-073320	Ornithorhynchus anatinus	82.00	0.00e+00	1026.00
IUUC-Ocu-073765	Oryctolagus cuniculus	81.66	0.00e+00	1003.00
IUUC-Oga-088002	Otolemur garnettii	85.23	0.00e+00	1067.00
IUUC-Oar-089481	Ovis aries	84.21	0.00e+00	1066.00
IUUC-Ptr-091200	Pan troglodytes	85.23	0.00e+00	1074.00
IUUC-Psi-093884	Pelodiscus sinensis	86.42	0.00e+00	1056.00
IUUC-Pva-102321	Pteropus vampyrus	84.38	0.00e+00	1063.00
IUUC-Rno-104835	Rattus norvegicus	83.36	0.00e+00	1022.00
IUUC-Sha-107528	Sarcophilus harrisii	86.93	0.00e+00	1092.00
IUUC-Ssc-116161	Sus scrofa	85.74	0.00e+00	1080.00
IUUC-Tgu-116569	Taeniopygia guttata	87.27	0.00e+00	1066.00
IUUC-Tni-120525	Tetraodon nigroviridis	82.74	0.00e+00	957.00
IUUC-Ttr-129297	Tursiops truncatus	85.40	0.00e+00	1076.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence