iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068809

Ensembl Protein ID

EAA30560

UniProt Accession

Q7S4V2; Q7S4V2_NEUCR

Genbank Protein ID

EAA30560.2

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM002242

Gene Name

NCU02375

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU02375	EAA30560	EAA30560

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-68	230.4	180	516

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalk.keaeefs...gyeqqDaqEfla 97
           G+ N g+tCY N vLQ+ ++ p lr+++l+   ++     + ++  +l++++ ++f+e++ +++++ ++  ++l+ ++ +e++ f+    +++qDa+Ef++
   Q: 180  GIYNAGATCYQNVVLQSFLHNPILRNFYLSD-GHQS---GSCDTPHCLSCAMDDMFQEFYaSETTNGYTAANILSGFWiSENKAFEnlvANKEQDAHEFFQ 276
           999***************************3.2222...2356789*************9855555566666666655155666888889*********** PP
   S: 98   flldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............. 185
           f+ ++l+e                 + +++++     +   +++i++++ g+l+++++c++c+ v+++ ++fldls+p+++ +++  +             
   Q: 277  FMAEELHERN--------------GDGKRPEI---GSEHTCNCIIHQTYYGKLQTSTTCQNCGGVTNQAQSFLDLSVPLENLTQKRGKknltngdgvastr 360
           ********99..............22334444...4567788**************************************877654447899********* PP
   S: 186  .....slqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfse.eqksrekinkkvefpleLdlspfctspeekqke..... 274
                +lq+cL e++ k ++ e    y c++c++ q+a++++++kklP+vL+++LkRf+f++ ++++ +ki++ v+fpl+L++ p++t+  +++ +     
   Q: 361  tqnsvTLQECLdEEYIKSDKCE----YRCQNCNSVQQARRQTSIKKLPNVLSIQLKRFEFKQgRNDRAQKIETPVQFPLQLNMLPYTTRARTQDLKdnyel 457
           ***********999*****999....**********************************983566889********************666665577777 PP
   S: 275  ..kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfY 335
             +++Y+L+ vvvH G ++ GHY++y++   ++W+ f+D+kV+  ++++vl+   ++aY+lfY
   Q: 458  qrSCTYDLLCVVVHVGDMDTGHYISYCRV-GDQWFAFNDHKVELAQKSDVLN---AKAYLLFY 516
           77***************************.889*******************...******** PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MSANAASSKD HKVKEPQPGQ PMYGCEHVGR LFNQDQATIN MSIQHYKTIL RAIFDINPIL 60
SHTAKGVDGQ VVTSITPTYL CLQCPSTLTD DDLTKHGNKK SHRFYVESRS GAVYCQMCDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATGTTGA CGCCGCGGAA ATCGGATGGA GATTCCAACC CCGAACAACT TCAAACCCAT 60
CTTGCTTCGG GAGAACCAAC ACAACCAGAG AAGATCCCTG TTGCTACTTT ACCGGCTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU02375

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	26.82	1.00e-36	146.00
IUUC-Aml-001343	Ailuropoda melanoleuca	29.68	2.00e-58	218.00
IUUC-Atr-002653	Amborella trichopoda	29.91	1.00e-54	205.00
IUUC-Apl-003433	Anas platyrhynchos	30.53	1.00e-56	212.00
IUUC-Aca-005347	Anolis carolinensis	28.49	7.00e-54	202.00
IUUC-Aly-006565	Arabidopsis lyrata	28.67	3.00e-44	171.00
IUUC-Ath-007536	Arabidopsis thaliana	28.35	8.00e-44	169.00
IUUC-Ago-007811	Ashbya gossypii	28.81	5.00e-48	183.00
IUUC-Acl-008124	Aspergillus clavatus	37.10	3.00e-91	327.00
IUUC-Afl-008464	Aspergillus flavus	38.48	5.00e-74	269.00
IUUC-Afu-008912	Aspergillus fumigatus	35.55	1.00e-84	305.00
IUUC-Ani-009168	Aspergillus nidulans	35.38	8.00e-86	309.00
IUUC-Ang-009694	Aspergillus niger	37.01	2.00e-89	320.00
IUUC-Aor-010035	Aspergillus oryzae	39.60	2.00e-50	190.00
IUUC-Ate-010382	Aspergillus terreus	37.53	2.00e-73	267.00
IUUC-Ame-011253	Astyanax mexicanus	29.70	2.00e-47	181.00
IUUC-Bgr-012150	Blumeria graminis	48.30	3.00e-146	509.00
IUUC-Bta-013303	Bos taurus	29.52	4.00e-60	223.00
IUUC-Bci-013604	Botrytis cinerea	57.09	2.00e-180	623.00
IUUC-Bdi-014171	Brachypodium distachyon	27.56	7.00e-46	176.00
IUUC-Bol-016509	Brassica oleracea	29.18	1.00e-48	186.00
IUUC-Bra-016962	Brassica rapa	28.82	6.00e-45	173.00
IUUC-Cel-018186	Caenorhabditis elegans	28.14	1.00e-29	122.00
IUUC-Cja-019283	Callithrix jacchus	31.94	2.00e-56	211.00
IUUC-Cfa-021239	Canis familiaris	31.25	4.00e-59	220.00
IUUC-Cpo-022354	Cavia porcellus	29.77	3.00e-59	221.00
IUUC-Csa-023145	Chlorocebus sabaeus	29.72	2.00e-60	224.00
IUUC-Cin-025109	Ciona intestinalis	30.10	3.00e-41	160.00
IUUC-Csv-026214	Ciona savignyi	31.12	1.00e-53	202.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	71.76	0.00e+00	787.00
IUUC-Cne-027085	Cryptococcus neoformans	27.08	3.00e-43	167.00
IUUC-Dre-027433	Danio rerio	30.07	3.00e-57	214.00
IUUC-Dno-030095	Dasypus novemcinctus	31.09	1.00e-58	218.00
IUUC-Dse-031415	Dothistroma septosporum	34.33	4.00e-92	330.00
IUUC-Dme-032074	Drosophila melanogaster	30.83	5.00e-50	190.00
IUUC-Ete-033175	Echinops telfairi	23.83	6.00e-33	133.00
IUUC-Eca-033736	Equus caballus	31.09	7.00e-59	219.00
IUUC-Eeu-035268	Erinaceus europaeus	25.91	5.00e-19	87.40
IUUC-Fca-035861	Felis catus	31.03	2.00e-58	218.00
IUUC-Fal-037645	Ficedula albicollis	30.53	1.00e-56	211.00
IUUC-Fox-038046	Fusarium oxysporum	70.08	0.00e+00	761.00
IUUC-Fso-038321	Fusarium solani	73.68	0.00e+00	656.00
IUUC-Gmo-038474	Gadus morhua	34.44	1.00e-35	142.00
IUUC-Ggr-040044	Gaeumannomyces graminis	70.60	0.00e+00	767.00
IUUC-Gga-040624	Gallus gallus	29.15	4.00e-57	213.00
IUUC-Gac-042197	Gasterosteus aculeatus	30.06	3.00e-53	201.00
IUUC-Gma-043469	Glycine max	31.30	3.00e-60	224.00
IUUC-Ggo-044409	Gorilla gorilla	29.54	1.00e-59	222.00
IUUC-Hsa-046521	Homo sapiens	29.72	2.00e-60	224.00
IUUC-Hvu-047739	Hordeum vulgare	28.88	2.00e-40	157.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	29.87	3.00e-59	220.00
IUUC-Kpa-049135	Komagataella pastoris	31.51	2.00e-65	241.00
IUUC-Lch-050537	Latimeria chalumnae	31.09	9.00e-58	216.00
IUUC-Lpe-050969	Leersia perrieri	27.71	1.00e-44	171.00
IUUC-Loc-052765	Lepisosteus oculatus	27.59	6.00e-49	186.00
IUUC-Lma-053105	Leptosphaeria maculans	40.19	2.00e-102	364.00
IUUC-Laf-053571	Loxodonta africana	31.30	3.00e-59	220.00
IUUC-Mcc-055166	Macaca mulatta	29.72	2.00e-60	224.00
IUUC-Meu-056697	Macropus eugenii	25.95	4.00e-22	99.00
IUUC-Mor-057103	Magnaporthe oryzae	64.69	0.00e+00	716.00
IUUC-Mpo-057621	Magnaporthe poae	69.06	0.00e+00	753.00
IUUC-Mtr-057894	Medicago truncatula	31.10	2.00e-58	218.00
IUUC-Mla-059185	Melampsora laricipopulina	29.77	7.00e-36	143.00
IUUC-Mga-059709	Meleagris gallopavo	30.53	1.00e-56	212.00
IUUC-Mvi-060530	Microbotryum violaceum	33.18	5.00e-50	189.00
IUUC-Mmr-060988	Microcebus murinus	29.71	7.00e-59	219.00
IUUC-Mdo-063065	Monodelphis domestica	31.09	1.00e-58	218.00
IUUC-Mmu-063829	Mus musculus	30.11	3.00e-60	224.00
IUUC-Mac-065419	Musa acuminata	29.16	9.00e-43	166.00
IUUC-Mpu-066687	Mustela putorius furo	30.06	9.00e-59	219.00
IUUC-Mlu-067330	Myotis lucifugus	30.40	4.00e-56	210.00
IUUC-Nfi-068423	Neosartorya fischeri	35.35	3.00e-84	303.00
IUUC-Nle-069261	Nomascus leucogenys	28.85	3.00e-53	201.00
IUUC-Opr-070469	Ochotona princeps	25.94	1.00e-39	155.00
IUUC-Ont-071961	Oreochromis niloticus	30.22	3.00e-54	204.00
IUUC-Oan-073565	Ornithorhynchus anatinus	28.71	9.00e-53	199.00
IUUC-Ocu-074435	Oryctolagus cuniculus	29.23	2.00e-56	211.00
IUUC-Oba-075688	Oryza barthii	28.50	2.00e-45	174.00
IUUC-Obr-076652	Oryza brachyantha	28.50	2.00e-45	174.00
IUUC-Ogl-077910	Oryza glaberrima	27.31	1.00e-47	182.00
IUUC-Ogu-078479	Oryza glumaepatula	27.53	4.00e-47	181.00
IUUC-Oin-079697	Oryza indica	28.15	6.00e-46	176.00
IUUC-Olo-080811	Oryza longistaminata	26.79	1.00e-29	121.00
IUUC-Ome-081706	Oryza meridionalis	27.31	2.00e-47	182.00
IUUC-Oni-083070	Oryza nivara	27.31	1.00e-47	182.00
IUUC-Opu-083605	Oryza punctata	27.40	3.00e-40	157.00
IUUC-Oru-084522	Oryza rufipogon	27.31	1.00e-47	182.00
IUUC-Osa-085351	Oryza sativa	28.09	3.00e-47	181.00
IUUC-Ola-086743	Oryzias latipes	32.50	5.00e-51	193.00
IUUC-Olu-087695	Ostreococcus lucimarinus	27.55	2.00e-35	140.00
IUUC-Oga-089131	Otolemur garnettii	29.17	1.00e-57	216.00
IUUC-Oar-089319	Ovis aries	31.30	1.00e-59	222.00
IUUC-Ptr-090783	Pan troglodytes	31.30	3.00e-59	221.00
IUUC-Pan-092927	Papio anubis	29.72	3.00e-60	224.00
IUUC-Psi-093670	Pelodiscus sinensis	30.53	1.00e-56	212.00
IUUC-Pma-094323	Petromyzon marinus	30.30	3.00e-50	191.00
IUUC-Pno-095141	Phaeosphaeria nodorum	38.51	3.00e-93	333.00
IUUC-Ppa-095413	Physcomitrella patens	30.29	6.00e-47	180.00
IUUC-Pfo-096462	Poecilia formosa	31.61	3.00e-57	214.00
IUUC-Pab-097612	Pongo abelii	29.72	2.00e-60	224.00
IUUC-Pop-099893	Populus trichocarpa	30.72	7.00e-52	196.00
IUUC-Pca-100329	Procavia capensis	30.48	2.00e-55	208.00
IUUC-Ppe-101583	Prunus persica	29.98	9.00e-50	189.00
IUUC-Pva-102721	Pteropus vampyrus	29.24	1.00e-51	195.00
IUUC-Pgr-103657	Puccinia graminis	24.02	4.00e-29	120.00
IUUC-Pte-104340	Pyrenophora teres	38.07	4.00e-94	336.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	39.39	5.00e-103	366.00
IUUC-Rno-105247	Rattus norvegicus	30.10	7.00e-60	223.00
IUUC-Sce-106247	Saccharomyces cerevisiae	28.57	4.00e-47	180.00
IUUC-Sha-107429	Sarcophilus harrisii	27.39	2.00e-23	102.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	31.54	5.00e-53	199.00
IUUC-Spo-108226	Schizosaccharomyces pombe	30.43	1.00e-59	222.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	55.11	3.00e-178	616.00
IUUC-Smo-109310	Selaginella moellendorffii	29.61	3.00e-54	204.00
IUUC-Sit-109716	Setaria italica	27.27	3.00e-47	181.00
IUUC-Sly-111077	Solanum lycopersicum	29.96	1.00e-50	192.00
IUUC-Stu-112203	Solanum tuberosum	31.12	7.00e-49	186.00
IUUC-Sar-113174	Sorex araneus	29.35	1.00e-47	182.00
IUUC-Sbi-114205	Sorghum bicolor	26.71	4.00e-46	177.00
IUUC-Sre-115195	Sporisorium reilianum	32.57	1.00e-29	123.00
IUUC-Ssc-115315	Sus scrofa	30.21	3.00e-56	210.00
IUUC-Tgu-116938	Taeniopygia guttata	31.09	1.00e-58	218.00
IUUC-Tru-117622	Takifugu rubripes	30.67	6.00e-56	209.00
IUUC-Tsy-119413	Tarsius syrichta	28.78	3.00e-51	194.00
IUUC-Tni-120119	Tetraodon nigroviridis	31.83	1.00e-56	212.00
IUUC-Tca-121154	Theobroma cacao	30.36	4.00e-54	204.00
IUUC-Tre-122139	Trichoderma reesei	72.97	0.00e+00	657.00
IUUC-Tvi-122599	Trichoderma virens	69.31	0.00e+00	780.00
IUUC-Tae-125608	Triticum aestivum	28.39	5.00e-53	200.00
IUUC-Tur-126423	Triticum urartu	27.30	4.00e-30	124.00
IUUC-Tme-127115	Tuber melanosporum	39.63	3.00e-105	373.00
IUUC-Ttr-129006	Tursiops truncatus	29.89	4.00e-54	203.00
IUUC-Uma-129455	Ustilago maydis	33.20	9.00e-32	130.00
IUUC-Vda-129829	Verticillium dahliae	75.76	1.00e-137	480.00
IUUC-Vvi-131477	Vitis vinifera	30.21	5.00e-41	160.00
IUUC-Xtr-132444	Xenopus tropicalis	30.32	5.00e-56	210.00
IUUC-Xma-133514	Xiphophorus maculatus	31.45	9.00e-58	216.00
IUUC-Yli-134357	Yarrowia lipolytica	29.59	3.00e-46	177.00
IUUC-Zma-134945	Zea mays	26.88	2.00e-46	178.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence