iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000006276.1	ENSPSIT00000006885.1	ENSPSIP00000006846.1
ENSPSIG00000006276.1	ENSPSIT00000006898.1	ENSPSIP00000006859.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-69	235.3	42	473

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsg 86
           Gl NlgNtC+mNS+LQ Ls++p++ + l +    +   ++n++++ ++l+ +l  l+++l     +++ +v+ + ll++l+ +  ++s+
   Q: 42   GLLNLGNTCFMNSLLQGLSACPSFIKWLEDfT-AQYKTDQNESSERQCLSLTLLCLLKALScqeVTEDDVVDASGLLEVLRLYRWQISS 129
           9*****************************42.333333445788899999999999999887799999******************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.s 164
           +e+qDa+E++++l ++le+e    ++ +++++++ ++ e++ e          + + ++ +++   ++ F+g+l+s++ c++c+++s +
   Q: 130  FEEQDAHELFHVLTSSLEDER--DRQPRITHLFDVHSLEQQPEvtpnqiscrtRGSLHPVSTHWKSQHPFHGRLTSNMLCKHCKQQSpV 216
           ********************9..6788889999999888888888999999888889999999************************99 PP
   S: 165  reepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfs 238
           r ++f +lsl++p      + +l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s
   Q: 217  RCDTFDSLSLSIPAAMWGRPMTLDHCLHHFISSESVKD---VVCDNCTkiqaegklngqitenQRTTFVKQLKLGKLPQCLCIHLQRLS 302
           ************************************97...9******5555555555555555555********************** PP
   S: 239  fseeqksrekinkkvefpleLdls..pfcts.....peekqke.............................................. 274
           +s++ +++ k n++v+f++ L ++  ++        +                                                    
   Q: 303  WSNQ-GMPLKRNEHVQFNEFLIMDiyKYHLPvhkssQ-----Pdlnqkgnpwmssetkdwgaptmavlqdleptcstksffmngacsps 385
           *996.8999*********8865552255555444440.....24445556777777777777777777777777777778888888888 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                               + Y+L+avvvH+G ++sGH+v+y ++          +++Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 386  lltspitfplaavpdcsspMYLYRLMAVVVHHGDMHSGHFVTYRRSpsspkaplsVSNQWLWISDDTVRKASLQEVLS---SSAYLLFY 471
           88888888888888888889**************************8887777776888*******************...******** PP
   S: 336  kr 337
           +r
   Q: 472  ER 473
           98 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

RHKIMKNWGV VGGIAAALAA GIYVLWGPIT ERKKHRKGLV PGLLNLGNTC FMNSLLQGLS 60
ACPSFIKWLE DFTAQYKTDQ NESSERQCLS LTLLCLLKAL SCQEVTEDDV VDASGLLEVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACAACAGA CTTTTCTCCT TCCTTTTTTA GGCATAAAAT AATGAAGAAC TGGGGTGTTG 60
TTGGAGGAAT AGCTGCTGCT CTGGCAGCAG GCATATATGT TCTCTGGGGT CCCATCACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	27.91	2.00e-20	93.60
IUUC-Aml-001733	Ailuropoda melanoleuca	75.65	0.00e+00	684.00
IUUC-Atr-002510	Amborella trichopoda	25.47	2.00e-22	100.00
IUUC-Apl-003645	Anas platyrhynchos	82.31	5.00e-124	436.00
IUUC-Aca-004583	Anolis carolinensis	69.74	3.00e-25	105.00
IUUC-Aly-005754	Arabidopsis lyrata	25.26	3.00e-26	112.00
IUUC-Ath-007622	Arabidopsis thaliana	27.69	4.00e-26	112.00
IUUC-Acl-008136	Aspergillus clavatus	21.48	7.00e-12	65.50
IUUC-Ame-010896	Astyanax mexicanus	62.22	1.00e-156	545.00
IUUC-Bgr-012133	Blumeria graminis	20.45	3.00e-09	56.60
IUUC-Bta-012321	Bos taurus	74.70	0.00e+00	672.00
IUUC-Bci-013590	Botrytis cinerea	22.71	3.00e-14	73.60
IUUC-Bdi-014795	Brachypodium distachyon	26.67	3.00e-15	76.30
IUUC-Bol-015637	Brassica oleracea	26.81	4.00e-23	102.00
IUUC-Bra-016801	Brassica rapa	25.84	4.00e-24	105.00
IUUC-Cel-018308	Caenorhabditis elegans	29.18	3.00e-37	149.00
IUUC-Cja-018826	Callithrix jacchus	77.08	0.00e+00	721.00
IUUC-Cfa-021206	Canis familiaris	76.06	0.00e+00	687.00
IUUC-Cpo-021343	Cavia porcellus	77.03	0.00e+00	698.00
IUUC-Csa-023419	Chlorocebus sabaeus	77.08	0.00e+00	723.00
IUUC-Cho-024475	Choloepus hoffmanni	69.68	5.00e-102	364.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.97	2.00e-12	67.40
IUUC-Cne-027061	Cryptococcus neoformans	25.52	5.00e-10	59.30
IUUC-Dre-027563	Danio rerio	61.89	5.00e-158	550.00
IUUC-Dno-029929	Dasypus novemcinctus	76.52	0.00e+00	698.00
IUUC-Dor-030166	Dipodomys ordii	67.48	3.00e-166	577.00
IUUC-Dme-031627	Drosophila melanogaster	35.92	2.00e-39	156.00
IUUC-Ete-032634	Echinops telfairi	69.17	9.00e-171	592.00
IUUC-Eca-033968	Equus caballus	76.22	0.00e+00	684.00
IUUC-Eeu-035279	Erinaceus europaeus	72.56	2.00e-51	196.00
IUUC-Fca-036525	Felis catus	76.32	0.00e+00	706.00
IUUC-Fal-036606	Ficedula albicollis	78.33	9.00e-168	582.00
IUUC-Fso-038309	Fusarium solani	22.67	2.00e-11	63.90
IUUC-Gmo-038726	Gadus morhua	57.82	8.00e-140	489.00
IUUC-Gga-040718	Gallus gallus	81.70	1.00e-177	615.00
IUUC-Gac-042645	Gasterosteus aculeatus	59.62	1.00e-149	522.00
IUUC-Gma-042890	Glycine max	25.65	5.00e-23	102.00
IUUC-Ggo-045021	Gorilla gorilla	77.48	0.00e+00	723.00
IUUC-Hsa-045832	Homo sapiens	77.48	0.00e+00	723.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	76.42	0.00e+00	690.00
IUUC-Kpa-049268	Komagataella pastoris	22.16	1.00e-13	71.20
IUUC-Lch-050662	Latimeria chalumnae	71.19	2.00e-173	601.00
IUUC-Lpe-051078	Leersia perrieri	28.17	4.00e-29	122.00
IUUC-Loc-052611	Lepisosteus oculatus	68.49	2.00e-179	621.00
IUUC-Lma-053048	Leptosphaeria maculans	20.24	4.00e-12	66.60
IUUC-Laf-053752	Loxodonta africana	76.32	0.00e+00	681.00
IUUC-Mcc-054892	Macaca mulatta	77.48	0.00e+00	726.00
IUUC-Meu-056673	Macropus eugenii	68.49	2.00e-146	511.00
IUUC-Mor-057143	Magnaporthe oryzae	22.32	6.00e-14	72.40
IUUC-Mtr-057976	Medicago truncatula	26.82	3.00e-33	136.00
IUUC-Mla-058970	Melampsora laricipopulina	21.24	1.00e-17	84.30
IUUC-Mga-059543	Meleagris gallopavo	83.44	0.00e+00	727.00
IUUC-Mmr-061534	Microcebus murinus	76.42	0.00e+00	702.00
IUUC-Mdo-062140	Monodelphis domestica	64.62	5.00e-157	547.00
IUUC-Mmu-063673	Mus musculus	74.80	0.00e+00	669.00
IUUC-Mpu-066328	Mustela putorius furo	75.81	0.00e+00	695.00
IUUC-Mlu-067938	Myotis lucifugus	76.32	0.00e+00	705.00
IUUC-Nfi-068306	Neosartorya fischeri	21.21	8.00e-14	71.60
IUUC-Nle-069426	Nomascus leucogenys	76.63	0.00e+00	669.00
IUUC-Opr-070796	Ochotona princeps	65.64	1.00e-92	333.00
IUUC-Ont-072248	Oreochromis niloticus	62.13	1.00e-153	535.00
IUUC-Oan-072916	Ornithorhynchus anatinus	77.51	0.00e+00	712.00
IUUC-Ocu-074459	Oryctolagus cuniculus	70.56	6.00e-156	543.00
IUUC-Oba-075765	Oryza barthii	26.12	2.00e-27	117.00
IUUC-Obr-076005	Oryza brachyantha	26.71	8.00e-26	111.00
IUUC-Ogl-077916	Oryza glaberrima	27.02	3.00e-30	126.00
IUUC-Ogu-078263	Oryza glumaepatula	26.32	9.00e-28	117.00
IUUC-Oin-080096	Oryza indica	26.26	3.00e-20	92.80
IUUC-Ome-081928	Oryza meridionalis	27.33	2.00e-27	116.00
IUUC-Oni-082424	Oryza nivara	26.32	9.00e-28	117.00
IUUC-Oru-085117	Oryza rufipogon	26.32	9.00e-28	117.00
IUUC-Ola-087429	Oryzias latipes	58.40	1.00e-141	495.00
IUUC-Oga-087981	Otolemur garnettii	76.42	0.00e+00	699.00
IUUC-Oar-089927	Ovis aries	75.30	0.00e+00	678.00
IUUC-Ptr-090878	Pan troglodytes	77.48	0.00e+00	723.00
IUUC-Pan-092698	Papio anubis	77.48	0.00e+00	726.00
IUUC-Pno-094855	Phaeosphaeria nodorum	24.02	2.00e-09	56.60
IUUC-Pfo-096096	Poecilia formosa	61.47	2.00e-149	521.00
IUUC-Pab-098676	Pongo abelii	76.27	0.00e+00	702.00
IUUC-Pca-100418	Procavia capensis	82.38	2.00e-111	395.00
IUUC-Ppe-101898	Prunus persica	25.05	3.00e-23	102.00
IUUC-Pva-103018	Pteropus vampyrus	74.55	0.00e+00	664.00
IUUC-Pgr-103686	Puccinia graminis	22.46	2.00e-11	64.30
IUUC-Pte-104330	Pyrenophora teres	21.50	5.00e-15	75.90
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.40	2.00e-16	81.30
IUUC-Rno-105708	Rattus norvegicus	74.59	0.00e+00	670.00
IUUC-Sha-106971	Sarcophilus harrisii	76.52	0.00e+00	708.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	22.66	6.00e-14	72.40
IUUC-Sit-110442	Setaria italica	28.99	4.00e-28	119.00
IUUC-Sly-110928	Solanum lycopersicum	25.56	1.00e-14	74.30
IUUC-Stu-112223	Solanum tuberosum	26.20	2.00e-14	73.20
IUUC-Ssc-116397	Sus scrofa	75.51	0.00e+00	678.00
IUUC-Tgu-117446	Taeniopygia guttata	71.87	0.00e+00	658.00
IUUC-Tru-118268	Takifugu rubripes	60.08	2.00e-142	498.00
IUUC-Tsy-119484	Tarsius syrichta	74.36	9.00e-40	157.00
IUUC-Tni-119735	Tetraodon nigroviridis	56.25	3.00e-123	434.00
IUUC-Tca-121660	Theobroma cacao	26.69	2.00e-27	117.00
IUUC-Tae-125383	Triticum aestivum	28.19	1.00e-27	117.00
IUUC-Tur-126458	Triticum urartu	28.75	1.00e-26	114.00
IUUC-Tbe-127740	Tupaia belangeri	69.84	3.00e-176	611.00
IUUC-Ttr-129273	Tursiops truncatus	75.60	0.00e+00	678.00
IUUC-Vvi-131177	Vitis vinifera	26.82	1.00e-26	114.00
IUUC-Xtr-132374	Xenopus tropicalis	66.46	9.00e-173	599.00
IUUC-Xma-133267	Xiphophorus maculatus	61.26	7.00e-152	530.00
IUUC-Zma-135796	Zea mays	26.34	6.00e-25	108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence