iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021711

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007350

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000024005.1	ENSCPOT00000019530.1	ENSCPOP00000014269.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.00e-19	69.7	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.70e-08	31.3	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+A+l+d+++L ++ +++ilk+F
   Q: 150  ENILDVYRLAELFDLSRLTEQLDTYILKNF 179
           8***************************** PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MAEEQEFTQL CKLPTQPSHP HCINNTYRST KHSQALLRGL LALRDSGILF DVVLVVEGRH 60
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAGG AGCAGGAGTT CACCCAGCTT TGTAAGTTGC CCACACAGCC CTCCCACCCA 60
CACTGCATCA ACAATACCTA CCGCAGTACA AAGCACTCCC AGGCTTTGCT CCGGGGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	96.53	0.00e+00	1231.00
IUUC-Apl-004081	Anas platyrhynchos	77.59	0.00e+00	1019.00
IUUC-Aca-005015	Anolis carolinensis	66.13	0.00e+00	855.00
IUUC-Ame-011712	Astyanax mexicanus	59.47	0.00e+00	724.00
IUUC-Bta-012594	Bos taurus	92.74	0.00e+00	1213.00
IUUC-Cja-019752	Callithrix jacchus	96.83	0.00e+00	1028.00
IUUC-Cfa-020884	Canis familiaris	96.85	0.00e+00	1265.00
IUUC-Csa-023211	Chlorocebus sabaeus	97.16	0.00e+00	1267.00
IUUC-Dre-028395	Danio rerio	60.75	0.00e+00	761.00
IUUC-Dno-030096	Dasypus novemcinctus	93.26	0.00e+00	1215.00
IUUC-Dor-030709	Dipodomys ordii	95.41	0.00e+00	706.00
IUUC-Eca-033388	Equus caballus	96.69	0.00e+00	1264.00
IUUC-Eeu-034616	Erinaceus europaeus	84.86	0.00e+00	1093.00
IUUC-Fca-035815	Felis catus	96.85	0.00e+00	1265.00
IUUC-Fal-037311	Ficedula albicollis	79.84	0.00e+00	1001.00
IUUC-Gmo-039571	Gadus morhua	52.43	4.00e-159	554.00
IUUC-Gga-040992	Gallus gallus	77.43	0.00e+00	1019.00
IUUC-Gac-042041	Gasterosteus aculeatus	55.80	0.00e+00	691.00
IUUC-Ggo-045141	Gorilla gorilla	91.48	0.00e+00	1191.00
IUUC-Hsa-045984	Homo sapiens	97.32	0.00e+00	1270.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	97.95	0.00e+00	1276.00
IUUC-Lch-049700	Latimeria chalumnae	60.97	0.00e+00	737.00
IUUC-Loc-052141	Lepisosteus oculatus	61.83	0.00e+00	814.00
IUUC-Laf-053487	Loxodonta africana	93.81	0.00e+00	1213.00
IUUC-Mcc-054682	Macaca mulatta	96.89	0.00e+00	1019.00
IUUC-Meu-055937	Macropus eugenii	74.61	0.00e+00	967.00
IUUC-Mga-059953	Meleagris gallopavo	77.43	0.00e+00	1019.00
IUUC-Mmr-061743	Microcebus murinus	96.53	0.00e+00	1254.00
IUUC-Mdo-062328	Monodelphis domestica	82.60	0.00e+00	1087.00
IUUC-Mmu-063979	Mus musculus	93.62	0.00e+00	1213.00
IUUC-Mpu-066750	Mustela putorius furo	96.69	0.00e+00	1262.00
IUUC-Mlu-066960	Myotis lucifugus	94.95	0.00e+00	1232.00
IUUC-Nle-069690	Nomascus leucogenys	97.67	0.00e+00	1139.00
IUUC-Opr-071059	Ochotona princeps	88.98	0.00e+00	1136.00
IUUC-Ont-072004	Oreochromis niloticus	58.47	0.00e+00	690.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.41	0.00e+00	739.00
IUUC-Ocu-074310	Oryctolagus cuniculus	95.08	3.00e-153	533.00
IUUC-Ola-086599	Oryzias latipes	57.54	0.00e+00	700.00
IUUC-Oga-087980	Otolemur garnettii	96.21	0.00e+00	1248.00
IUUC-Oar-089956	Ovis aries	77.69	0.00e+00	910.00
IUUC-Ptr-090598	Pan troglodytes	97.50	0.00e+00	1142.00
IUUC-Pan-092387	Papio anubis	96.69	0.00e+00	1019.00
IUUC-Psi-093484	Pelodiscus sinensis	78.84	0.00e+00	1051.00
IUUC-Pma-094224	Petromyzon marinus	49.59	7.00e-173	600.00
IUUC-Pfo-096149	Poecilia formosa	57.46	0.00e+00	709.00
IUUC-Pab-098097	Pongo abelii	97.16	0.00e+00	1271.00
IUUC-Pca-100118	Procavia capensis	94.32	0.00e+00	695.00
IUUC-Pva-103174	Pteropus vampyrus	95.44	4.00e-154	538.00
IUUC-Rno-105350	Rattus norvegicus	93.99	0.00e+00	1200.00
IUUC-Sha-106817	Sarcophilus harrisii	83.52	6.00e-135	474.00
IUUC-Sar-113490	Sorex araneus	94.75	0.00e+00	644.00
IUUC-Ssc-115827	Sus scrofa	94.48	0.00e+00	1239.00
IUUC-Tgu-116748	Taeniopygia guttata	82.13	0.00e+00	895.00
IUUC-Tru-118644	Takifugu rubripes	58.36	0.00e+00	700.00
IUUC-Tsy-118888	Tarsius syrichta	90.14	0.00e+00	1034.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.97	2.00e-177	615.00
IUUC-Ttr-129183	Tursiops truncatus	94.62	0.00e+00	1108.00
IUUC-Xtr-132780	Xenopus tropicalis	68.37	0.00e+00	900.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence