iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052791

Ensembl Protein ID

ENSLOCP00000005211.1

UniProt Accession

W5MA02; W5MA02_LEPOC

Genbank Protein ID

ENSLOCP00000005211

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01005106

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000004355.1	ENSLOCT00000005219.1	ENSLOCP00000005211.1
ENSLOCG00000004355.1	ENSLOCT00000005232.1	ENSLOCP00000005224.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.10e-113	377.6	709	1073

Active Site

Position(s)	Description	Evidence
1041	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf++++++ e l+p+p+s++++ +hl+lFef+G++lgka+++g
   Q: 709  SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFRTTSGN-ERLYPSPTSYIHE-NHLQLFEFVGKMLGKAVYEG 793
           578899****************************************888765.5669*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + d+++lgl+l+++  e+++g+  ++eL+pgG++ipVtn
   Q: 794  IVVDVPFASFFLSQVLGHhhstfYSSIDELPSLDSEFYKNLTSIKKRYDGDVSDLGLTLSYD--EDVMGQLVCHELIPGGKTIPVTN 878
           ******************777777999********************999999988888775..889******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ik q++af +Gf+ +i++e+l +F++ e++ li+G+ +eid+edlkk+t y gg+++++++i+w+w++l
   Q: 879  ENKISYIHLMAHFRMHTQIKDQTTAFIRGFRCIINPEWLHMFSTPEVQRLISGDnAEIDLEDLKKHTVYYGGFHSSHRVIIWLWDIL 965
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f++eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+
   Q: 966  sNDFTAEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSK 1052
           999************************************************************9999******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1053 KSILRDKLRYAISMNTGFELS 1073
           ******************985 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MFGTVQSSKS QFLDKARQAR EERKGQKERE KAATQIQALV RRFLCRCKLQ KQIRKEVDEF 60
FEACDTGSWK RNALSIFKIA RKLLFIFNLK EDKVSHDRFE KLCRCILGSM EVENEPKVWY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGAAATC CCACACATGC AAAAATAGTT CCATTGCTGC ATGAAAATTC GTTATTTTAA 60
AAGGAGTAAT GCAAAAAAAA TCAGTATAGC GTGAAATTTG TGACTGTAAT TATACTGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.75	4.00e-106	379.00
IUUC-Aml-002107	Ailuropoda melanoleuca	83.05	0.00e+00	1824.00
IUUC-Atr-003017	Amborella trichopoda	39.47	2.00e-111	397.00
IUUC-Apl-003328	Anas platyrhynchos	86.21	0.00e+00	1808.00
IUUC-Aly-005794	Arabidopsis lyrata	39.57	2.00e-107	384.00
IUUC-Ath-007269	Arabidopsis thaliana	39.93	3.00e-110	393.00
IUUC-Bta-013547	Bos taurus	83.05	0.00e+00	1856.00
IUUC-Bdi-014502	Brachypodium distachyon	39.43	9.00e-110	391.00
IUUC-Bol-015093	Brassica oleracea	40.46	2.00e-111	397.00
IUUC-Bra-016722	Brassica rapa	40.46	3.00e-112	399.00
IUUC-Cel-018447	Caenorhabditis elegans	37.93	0.00e+00	689.00
IUUC-Cja-019855	Callithrix jacchus	82.68	0.00e+00	1812.00
IUUC-Cfa-020066	Canis familiaris	82.78	0.00e+00	1803.00
IUUC-Cpo-021504	Cavia porcellus	82.39	0.00e+00	1837.00
IUUC-Csa-023579	Chlorocebus sabaeus	82.87	0.00e+00	1820.00
IUUC-Cho-024430	Choloepus hoffmanni	72.82	0.00e+00	1321.00
IUUC-Cin-025750	Ciona intestinalis	45.89	0.00e+00	948.00
IUUC-Csv-026016	Ciona savignyi	47.85	0.00e+00	1013.00
IUUC-Dre-028271	Danio rerio	90.97	0.00e+00	1934.00
IUUC-Dno-029054	Dasypus novemcinctus	83.43	0.00e+00	1831.00
IUUC-Dor-030938	Dipodomys ordii	76.79	0.00e+00	1644.00
IUUC-Dme-031602	Drosophila melanogaster	48.53	0.00e+00	970.00
IUUC-Ete-033041	Echinops telfairi	67.59	0.00e+00	1208.00
IUUC-Eca-034411	Equus caballus	83.61	0.00e+00	1815.00
IUUC-Eeu-035201	Erinaceus europaeus	77.20	0.00e+00	744.00
IUUC-Fca-036594	Felis catus	82.03	0.00e+00	1791.00
IUUC-Fal-037317	Ficedula albicollis	82.93	0.00e+00	1833.00
IUUC-Gmo-039412	Gadus morhua	86.68	0.00e+00	1911.00
IUUC-Gga-040149	Gallus gallus	86.59	0.00e+00	1855.00
IUUC-Gac-042088	Gasterosteus aculeatus	90.59	0.00e+00	1996.00
IUUC-Gma-042728	Glycine max	40.96	3.00e-111	396.00
IUUC-Ggo-045279	Gorilla gorilla	82.68	0.00e+00	1813.00
IUUC-Hsa-045660	Homo sapiens	82.50	0.00e+00	1809.00
IUUC-Hvu-047102	Hordeum vulgare	36.89	4.00e-106	379.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	76.37	0.00e+00	875.00
IUUC-Lch-050664	Latimeria chalumnae	87.81	0.00e+00	1914.00
IUUC-Lpe-050755	Leersia perrieri	37.30	6.00e-97	348.00
IUUC-Laf-053902	Loxodonta africana	83.61	0.00e+00	1837.00
IUUC-Mcc-054730	Macaca mulatta	82.77	0.00e+00	1819.00
IUUC-Meu-056527	Macropus eugenii	78.16	0.00e+00	1650.00
IUUC-Mtr-057671	Medicago truncatula	40.43	6.00e-111	395.00
IUUC-Mga-059260	Meleagris gallopavo	86.25	0.00e+00	1851.00
IUUC-Mmr-060804	Microcebus murinus	81.92	0.00e+00	1771.00
IUUC-Mdo-062575	Monodelphis domestica	81.77	0.00e+00	1749.00
IUUC-Mmu-063636	Mus musculus	80.91	0.00e+00	1736.00
IUUC-Mac-064989	Musa acuminata	39.93	9.00e-109	388.00
IUUC-Mpu-066677	Mustela putorius furo	81.90	0.00e+00	1696.00
IUUC-Mlu-067952	Myotis lucifugus	83.32	0.00e+00	1774.00
IUUC-Nle-069153	Nomascus leucogenys	82.68	0.00e+00	1813.00
IUUC-Opr-070554	Ochotona princeps	83.47	0.00e+00	1675.00
IUUC-Ont-071372	Oreochromis niloticus	91.99	0.00e+00	1972.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.21	0.00e+00	747.00
IUUC-Ocu-074183	Oryctolagus cuniculus	82.03	0.00e+00	1792.00
IUUC-Oba-075213	Oryza barthii	39.30	5.00e-106	379.00
IUUC-Obr-076320	Oryza brachyantha	39.89	1.00e-108	387.00
IUUC-Ogl-077093	Oryza glaberrima	39.65	1.00e-108	387.00
IUUC-Ogu-078947	Oryza glumaepatula	37.54	9.00e-111	395.00
IUUC-Oin-080058	Oryza indica	39.55	2.00e-108	387.00
IUUC-Olo-080742	Oryza longistaminata	39.37	6.00e-108	386.00
IUUC-Ome-081741	Oryza meridionalis	39.15	2.00e-101	363.00
IUUC-Oni-082385	Oryza nivara	37.54	9.00e-111	394.00
IUUC-Opu-083529	Oryza punctata	39.65	3.00e-108	387.00
IUUC-Oru-085128	Oryza rufipogon	36.98	4.00e-95	343.00
IUUC-Osa-085557	Oryza sativa	39.55	5.00e-108	385.00
IUUC-Ola-087337	Oryzias latipes	91.33	0.00e+00	1915.00
IUUC-Oga-088342	Otolemur garnettii	82.14	0.00e+00	1736.00
IUUC-Oar-090234	Ovis aries	82.50	0.00e+00	1826.00
IUUC-Ptr-091661	Pan troglodytes	82.68	0.00e+00	1813.00
IUUC-Pan-092728	Papio anubis	82.60	0.00e+00	1814.00
IUUC-Psi-093251	Pelodiscus sinensis	85.46	0.00e+00	1720.00
IUUC-Pma-094195	Petromyzon marinus	71.34	0.00e+00	1477.00
IUUC-Ppa-095544	Physcomitrella patens	38.46	1.00e-110	394.00
IUUC-Pfo-097472	Poecilia formosa	91.99	0.00e+00	1981.00
IUUC-Pab-098570	Pongo abelii	82.87	0.00e+00	1815.00
IUUC-Pca-100110	Procavia capensis	72.35	0.00e+00	1519.00
IUUC-Ppe-101281	Prunus persica	39.47	2.00e-106	380.00
IUUC-Pva-102887	Pteropus vampyrus	78.33	0.00e+00	1684.00
IUUC-Rno-106028	Rattus norvegicus	78.88	0.00e+00	1649.00
IUUC-Sha-107331	Sarcophilus harrisii	82.53	0.00e+00	1773.00
IUUC-Smo-109488	Selaginella moellendorffii	38.08	1.00e-106	381.00
IUUC-Sit-109811	Setaria italica	39.54	4.00e-108	385.00
IUUC-Sar-113287	Sorex araneus	68.75	8.00e-170	590.00
IUUC-Sbi-114433	Sorghum bicolor	36.90	2.00e-109	390.00
IUUC-Ssc-116103	Sus scrofa	83.52	0.00e+00	1815.00
IUUC-Tgu-117275	Taeniopygia guttata	85.75	0.00e+00	1833.00
IUUC-Tru-118681	Takifugu rubripes	90.40	0.00e+00	1991.00
IUUC-Tsy-118985	Tarsius syrichta	74.32	0.00e+00	859.00
IUUC-Tni-120850	Tetraodon nigroviridis	97.00	0.00e+00	811.00
IUUC-Tca-121770	Theobroma cacao	39.47	1.00e-110	394.00
IUUC-Tae-125466	Triticum aestivum	37.01	3.00e-106	380.00
IUUC-Tur-126086	Triticum urartu	40.25	2.00e-105	377.00
IUUC-Tbe-127461	Tupaia belangeri	79.07	0.00e+00	1667.00
IUUC-Ttr-129269	Tursiops truncatus	82.87	0.00e+00	1795.00
IUUC-Vpa-130523	Vicugna pacos	75.17	3.00e-115	409.00
IUUC-Vvi-131524	Vitis vinifera	39.61	6.00e-109	389.00
IUUC-Xtr-132146	Xenopus tropicalis	83.64	0.00e+00	1846.00
IUUC-Xma-133526	Xiphophorus maculatus	91.33	0.00e+00	1971.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence