iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093099

Ensembl Protein ID

ENSPSIP00000012177.1

UniProt Accession

K7FVW7; K7FVW7_PELSI

Genbank Protein ID

ENSPSIP00000012177

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01112133

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010986.1	ENSPSIT00000012235.1	ENSPSIP00000012177.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.20e-12	46.7	116	158

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 6    llrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +l ++ +SLqh CR++I++c+ +     i++LPLP +Lk+YL++++yq
   Q: 116  PLYTSTPSLQHRCRITINKCTSK-----IWELPLPTRLKEYLKEYQYQ 158
           677889***************99.....8****************986 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MEELRRAGWY WGNMNVAEAK ERLQDTPEGT FLVRDSSHSE YLLTISVKTS AGPTNLRIEY 60
QNGKFRLDSI ICVRSRLKQF DSVVDLIEYY VLTCKDRKTG PETPPNGTVH LYLNKPLYTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNGTG 60
ACCGAGAGTG CGGCGGCGGA GCGCCTGGCC GCGGCGATGG AGGAGCTGAG GCGGGCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

KEGG

pss:102453265

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	76.10	1.00e-72	265.00
IUUC-Apl-003484	Anas platyrhynchos	88.82	1.00e-77	281.00
IUUC-Aca-004253	Anolis carolinensis	83.02	4.00e-78	283.00
IUUC-Ame-011267	Astyanax mexicanus	60.12	7.00e-55	206.00
IUUC-Bta-013183	Bos taurus	78.95	2.00e-72	264.00
IUUC-Cja-018862	Callithrix jacchus	77.92	1.00e-72	265.00
IUUC-Cfa-020226	Canis familiaris	78.43	1.00e-71	261.00
IUUC-Cpo-022414	Cavia porcellus	79.61	2.00e-72	264.00
IUUC-Csa-023758	Chlorocebus sabaeus	77.92	4.00e-72	263.00
IUUC-Cho-024471	Choloepus hoffmanni	72.61	8.00e-61	225.00
IUUC-Dre-028288	Danio rerio	61.96	2.00e-56	211.00
IUUC-Dno-029036	Dasypus novemcinctus	76.73	1.00e-73	268.00
IUUC-Dor-030447	Dipodomys ordii	78.81	2.00e-71	260.00
IUUC-Ete-033023	Echinops telfairi	77.36	1.00e-73	268.00
IUUC-Fca-036469	Felis catus	77.92	4.00e-72	263.00
IUUC-Fal-036642	Ficedula albicollis	87.10	4.00e-77	280.00
IUUC-Gmo-039331	Gadus morhua	62.07	3.00e-31	126.00
IUUC-Gga-040809	Gallus gallus	89.94	5.00e-82	295.00
IUUC-Gac-041398	Gasterosteus aculeatus	59.38	2.00e-54	204.00
IUUC-Ggo-045341	Gorilla gorilla	78.57	9.00e-73	265.00
IUUC-Hsa-046557	Homo sapiens	77.36	5.00e-74	270.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	76.77	1.00e-71	261.00
IUUC-Lch-050160	Latimeria chalumnae	65.49	4.00e-52	196.00
IUUC-Loc-051825	Lepisosteus oculatus	63.35	1.00e-58	218.00
IUUC-Laf-053560	Loxodonta africana	77.27	6.00e-71	259.00
IUUC-Mcc-055890	Macaca mulatta	77.27	1.00e-71	261.00
IUUC-Meu-056218	Macropus eugenii	81.76	3.00e-78	283.00
IUUC-Mga-059755	Meleagris gallopavo	89.47	1.00e-77	281.00
IUUC-Mmr-061387	Microcebus murinus	77.92	4.00e-72	263.00
IUUC-Mdo-062383	Monodelphis domestica	83.02	9.00e-79	285.00
IUUC-Mmu-063443	Mus musculus	76.62	6.00e-71	259.00
IUUC-Mpu-066459	Mustela putorius furo	76.62	1.00e-70	258.00
IUUC-Mlu-068040	Myotis lucifugus	76.73	2.00e-73	267.00
IUUC-Nle-069016	Nomascus leucogenys	79.61	2.00e-72	264.00
IUUC-Opr-071087	Ochotona princeps	75.66	1.00e-69	255.00
IUUC-Ont-072340	Oreochromis niloticus	59.64	5.00e-56	209.00
IUUC-Oan-073443	Ornithorhynchus anatinus	83.65	2.00e-78	284.00
IUUC-Ocu-074539	Oryctolagus cuniculus	76.47	6.00e-70	256.00
IUUC-Ola-087004	Oryzias latipes	56.96	1.00e-51	194.00
IUUC-Oga-088438	Otolemur garnettii	78.57	2.00e-72	264.00
IUUC-Oar-089932	Ovis aries	80.26	4.00e-73	266.00
IUUC-Ptr-091037	Pan troglodytes	78.57	9.00e-73	265.00
IUUC-Pan-092767	Papio anubis	77.92	3.00e-72	263.00
IUUC-Pfo-097073	Poecilia formosa	54.04	2.00e-49	188.00
IUUC-Pab-098319	Pongo abelii	77.36	6.00e-74	269.00
IUUC-Pca-101117	Procavia capensis	77.92	7.00e-71	259.00
IUUC-Pva-102117	Pteropus vampyrus	78.29	4.00e-71	260.00
IUUC-Rno-105913	Rattus norvegicus	75.97	7.00e-70	256.00
IUUC-Sha-106500	Sarcophilus harrisii	82.28	2.00e-77	281.00
IUUC-Ssc-115252	Sus scrofa	78.95	7.00e-72	262.00
IUUC-Tgu-117524	Taeniopygia guttata	88.05	2.00e-79	287.00
IUUC-Tsy-119335	Tarsius syrichta	77.48	1.00e-70	257.00
IUUC-Tni-120263	Tetraodon nigroviridis	57.40	2.00e-52	197.00
IUUC-Tbe-127915	Tupaia belangeri	77.92	1.00e-71	261.00
IUUC-Ttr-128372	Tursiops truncatus	77.92	7.00e-72	262.00
IUUC-Vpa-130422	Vicugna pacos	78.81	4.00e-71	259.00
IUUC-Xtr-132941	Xenopus tropicalis	77.99	1.00e-71	261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence