iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000040481.17	ENSMUST00000106763.7	ENSMUSP00000102374.1
ENSMUSG00000040481.17	ENSMUST00000106762.7	ENSMUSP00000102373.1
ENSMUSG00000040481.17	ENSMUST00000208369.1	ENSMUSP00000146600.1
ENSMUSG00000040481.17	ENSMUST00000133317.1	ENSMUSP00000118875.1
ENSMUSG00000040481.17	ENSMUST00000149486.1	ENSMUSP00000122575.1
ENSMUSG00000040481.17	ENSMUST00000057892.14	ENSMUSP00000052303.8

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-14	54.8	2859	2907

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           +C +C+ +++++k  + C++C++w+H +C+++  ++e    +++ Cp+C+s
   Q: 2859 YC-ICKTPYDESKFYIGCDRCQNWYHGRCVGIL-QSEADLIDEYVCPQCQS 2907
           89.*****************************9.888888888******87 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MRGRRGRPPK QPAAPAAERC APAPPPPPPP PPPPPPPPPP PPPASGPIGG LRSRHRGSSR 60
GRWAAAQAEV APKTRLSSPR GGGRRKQPPP PPPASGSSAS GPGRGGRGGG GGRTGGGGGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAACAAGAT GGCGGCTGCA GGCGATCCGG AGCGGGGCCC CGGCAATTCG GACTGAGCCT 60
TCTCCCTCCA CCCCGCCGCT GCCGGGCCGC GCCCCTCCCG CCCGGACCCC GGCGCCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR018501--DDT_dom
IPR028942--WHIM1_dom
IPR028941--WHIM2_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50827--DDT
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF02791--DDT
PF00628--PHD
PF15612--WHIM1
PF15613--WSD

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00571--DDT
SM00249--PHD

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0016589--C:NURF complex
GO:0043565--F:sequence-specific DNA binding
GO:0008134--F:transcription factor binding
GO:0008270--F:zinc ion binding
GO:0009952--P:anterior/posterior pattern specification
GO:0007420--P:brain development
GO:0006338--P:chromatin remodeling
GO:0001892--P:embryonic placenta development
GO:0007492--P:endoderm development
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000221	Aegilops tauschii	28.74	4.00e-11	65.10
IUUC-Aml-001431	Ailuropoda melanoleuca	80.31	0.00e+00	3039.00
IUUC-Apl-003251	Anas platyrhynchos	60.35	0.00e+00	1305.00
IUUC-Aca-005148	Anolis carolinensis	70.52	2.00e-151	530.00
IUUC-Ame-011093	Astyanax mexicanus	54.96	1.00e-151	532.00
IUUC-Bta-012701	Bos taurus	79.92	0.00e+00	3070.00
IUUC-Bol-015269	Brassica oleracea	26.62	5.00e-17	84.30
IUUC-Bra-018092	Brassica rapa	26.26	2.00e-16	82.40
IUUC-Cel-018283	Caenorhabditis elegans	34.32	2.00e-54	208.00
IUUC-Cja-018809	Callithrix jacchus	83.88	1.00e-166	580.00
IUUC-Cfa-021079	Canis familiaris	79.85	0.00e+00	3105.00
IUUC-Cpo-021892	Cavia porcellus	76.03	0.00e+00	1823.00
IUUC-Csa-023142	Chlorocebus sabaeus	78.39	0.00e+00	3096.00
IUUC-Cho-024758	Choloepus hoffmanni	70.37	0.00e+00	1019.00
IUUC-Cin-025225	Ciona intestinalis	52.85	1.00e-41	164.00
IUUC-Csv-026235	Ciona savignyi	49.71	6.00e-56	210.00
IUUC-Dre-028054	Danio rerio	74.41	2.00e-172	601.00
IUUC-Dno-029508	Dasypus novemcinctus	69.45	0.00e+00	1561.00
IUUC-Dor-030950	Dipodomys ordii	61.93	0.00e+00	724.00
IUUC-Dme-032140	Drosophila melanogaster	50.44	4.00e-101	364.00
IUUC-Ete-032789	Echinops telfairi	70.58	0.00e+00	1797.00
IUUC-Eca-033972	Equus caballus	79.62	0.00e+00	3042.00
IUUC-Eeu-034541	Erinaceus europaeus	68.47	0.00e+00	1070.00
IUUC-Fca-036272	Felis catus	78.50	0.00e+00	2120.00
IUUC-Fal-037141	Ficedula albicollis	63.70	0.00e+00	2055.00
IUUC-Gmo-039453	Gadus morhua	76.36	2.00e-168	588.00
IUUC-Gga-040833	Gallus gallus	60.31	0.00e+00	2136.00
IUUC-Gac-042513	Gasterosteus aculeatus	72.35	0.00e+00	658.00
IUUC-Ggo-045377	Gorilla gorilla	84.02	8.00e-173	601.00
IUUC-Hsa-046878	Homo sapiens	79.54	0.00e+00	3051.00
IUUC-Hvu-047760	Hordeum vulgare	25.46	4.00e-17	84.70
IUUC-Itr-048740	Ictidomys tridecemlineatus	78.71	0.00e+00	1989.00
IUUC-Lch-049744	Latimeria chalumnae	58.09	0.00e+00	1905.00
IUUC-Loc-052694	Lepisosteus oculatus	71.10	0.00e+00	642.00
IUUC-Laf-054223	Loxodonta africana	79.79	0.00e+00	2936.00
IUUC-Mcc-054601	Macaca mulatta	80.01	0.00e+00	3083.00
IUUC-Mtr-058758	Medicago truncatula	25.77	9.00e-21	97.10
IUUC-Mga-060204	Meleagris gallopavo	59.90	0.00e+00	1862.00
IUUC-Mmr-061332	Microcebus murinus	78.73	0.00e+00	2069.00
IUUC-Mdo-062245	Monodelphis domestica	67.50	0.00e+00	2477.00
IUUC-Mac-065252	Musa acuminata	24.45	4.00e-18	87.80
IUUC-Mpu-066289	Mustela putorius furo	77.90	0.00e+00	3018.00
IUUC-Mlu-066991	Myotis lucifugus	79.17	0.00e+00	3020.00
IUUC-Nle-070095	Nomascus leucogenys	80.15	0.00e+00	3077.00
IUUC-Ont-071778	Oreochromis niloticus	77.99	0.00e+00	649.00
IUUC-Oan-073261	Ornithorhynchus anatinus	64.18	0.00e+00	2289.00
IUUC-Ocu-074848	Oryctolagus cuniculus	78.11	0.00e+00	3591.00
IUUC-Ogu-078676	Oryza glumaepatula	22.28	8.00e-17	84.00
IUUC-Olo-080881	Oryza longistaminata	25.00	1.00e-15	79.30
IUUC-Ome-081742	Oryza meridionalis	25.00	2.00e-16	82.00
IUUC-Oru-084745	Oryza rufipogon	22.28	8.00e-17	84.00
IUUC-Ola-086685	Oryzias latipes	74.27	0.00e+00	635.00
IUUC-Oga-088994	Otolemur garnettii	80.11	0.00e+00	3021.00
IUUC-Oar-090271	Ovis aries	79.82	0.00e+00	3033.00
IUUC-Ptr-090821	Pan troglodytes	79.67	0.00e+00	3058.00
IUUC-Pan-092346	Papio anubis	66.45	6.00e-104	372.00
IUUC-Psi-093425	Pelodiscus sinensis	68.24	0.00e+00	1480.00
IUUC-Pma-094355	Petromyzon marinus	65.04	8.00e-148	519.00
IUUC-Pno-094853	Phaeosphaeria nodorum	39.73	6.00e-16	79.70
IUUC-Pfo-096749	Poecilia formosa	69.29	0.00e+00	654.00
IUUC-Pab-098056	Pongo abelii	77.76	0.00e+00	3018.00
IUUC-Pop-099219	Populus trichocarpa	29.17	2.00e-14	76.30
IUUC-Pca-100922	Procavia capensis	76.37	0.00e+00	2036.00
IUUC-Pva-103167	Pteropus vampyrus	77.50	0.00e+00	1996.00
IUUC-Pgr-103292	Puccinia graminis	50.00	2.00e-14	73.60
IUUC-Ptt-104009	Puccinia triticina	42.50	1.00e-16	80.90
IUUC-Rno-105749	Rattus norvegicus	88.82	0.00e+00	3347.00
IUUC-Sha-106874	Sarcophilus harrisii	67.55	0.00e+00	2391.00
IUUC-Sja-107953	Schizosaccharomyces japonicus	50.00	2.00e-13	70.50
IUUC-Sly-111813	Solanum lycopersicum	28.22	1.00e-11	66.60
IUUC-Stu-112841	Solanum tuberosum	42.55	4.00e-10	58.50
IUUC-Sar-113725	Sorex araneus	82.92	0.00e+00	786.00
IUUC-Tgu-117339	Taeniopygia guttata	95.51	7.00e-110	392.00
IUUC-Tru-118620	Takifugu rubripes	58.32	0.00e+00	1079.00
IUUC-Tni-120313	Tetraodon nigroviridis	51.97	0.00e+00	988.00
IUUC-Tbe-127684	Tupaia belangeri	70.40	0.00e+00	1702.00
IUUC-Ttr-128434	Tursiops truncatus	76.13	0.00e+00	1947.00
IUUC-Vpa-130338	Vicugna pacos	75.19	0.00e+00	1035.00
IUUC-Xtr-132434	Xenopus tropicalis	60.62	0.00e+00	1168.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence