iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054098

Ensembl Protein ID

ENSLAFP00000023884.1

UniProt Accession

G3U7S6; G3U7S6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KDM5C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000303.2	ENSLAFT00000027692.1	ENSLAFP00000023884.1
ENSLAFG00000000303.2	ENSLAFT00000037012.1	ENSLAFP00000028479.1
ENSLAFG00000000303.2	ENSLAFT00000000304.2	ENSLAFP00000000253.2
ENSLAFG00000000303.2	ENSLAFT00000032669.1	ENSLAFP00000020281.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.20e-10	39.7	327	373

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C +C +g+ed+ +l+ C+ C++++H  Cl ++  +e p+   w CpkC 
   Q: 327  ICRMCSRGDEDD-KLLLCDGCDDNYHIFCLLPP-LPEIPKGV-WRCPKCV 373
           7*********88.6*******************.*******8.******6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEPGSDDFLP PPECPVFEPS WEFPRTRLAY IGEKIRPIAG GSPGICKIRP PADWQPPFAV 60
EVDTSVYPRI QLIELDSAQT RVKLNYLDQI AKFWEIQGSS LKIPNVERRI LDLYSLSKIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCAG GGTCCGACGA CTTCCTACCG CCGCCGGAGT GCCCGGTGTT CGAGCCCAGC 60
TGGGGCCGAG TTTCCGAGAA CCCGCTTGGC TTACATCGGC GAAAAAATCA GGCCCATTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0003677--F:DNA binding
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001327	Ailuropoda melanoleuca	88.67	0.00e+00	2355.00
IUUC-Apl-003524	Anas platyrhynchos	89.14	0.00e+00	1182.00
IUUC-Aca-004712	Anolis carolinensis	76.02	0.00e+00	1847.00
IUUC-Bta-013099	Bos taurus	96.57	0.00e+00	1618.00
IUUC-Cja-018723	Callithrix jacchus	94.77	0.00e+00	1563.00
IUUC-Cfa-020954	Canis familiaris	88.25	0.00e+00	2307.00
IUUC-Cpo-021718	Cavia porcellus	94.48	0.00e+00	1304.00
IUUC-Csa-023946	Chlorocebus sabaeus	87.81	0.00e+00	2303.00
IUUC-Dre-028238	Danio rerio	60.04	0.00e+00	1707.00
IUUC-Dno-029435	Dasypus novemcinctus	96.79	0.00e+00	1615.00
IUUC-Dor-030226	Dipodomys ordii	81.64	0.00e+00	1572.00
IUUC-Dse-031479	Dothistroma septosporum	28.16	8.00e-103	369.00
IUUC-Eca-033834	Equus caballus	88.99	0.00e+00	2384.00
IUUC-Eeu-034692	Erinaceus europaeus	85.81	0.00e+00	1743.00
IUUC-Fca-035766	Felis catus	91.34	0.00e+00	1492.00
IUUC-Fso-038127	Fusarium solani	30.75	6.00e-108	386.00
IUUC-Gmo-039140	Gadus morhua	61.47	0.00e+00	1619.00
IUUC-Gac-041825	Gasterosteus aculeatus	60.70	0.00e+00	1662.00
IUUC-Ggo-045492	Gorilla gorilla	88.33	0.00e+00	2385.00
IUUC-Hsa-046737	Homo sapiens	88.15	0.00e+00	2364.00
IUUC-Itr-048348	Ictidomys tridecemlineatus	87.89	0.00e+00	2419.00
IUUC-Lch-050517	Latimeria chalumnae	81.16	0.00e+00	1385.00
IUUC-Mcc-055740	Macaca mulatta	88.09	0.00e+00	2380.00
IUUC-Meu-056643	Macropus eugenii	78.34	0.00e+00	2036.00
IUUC-Mmr-061032	Microcebus murinus	96.79	0.00e+00	1618.00
IUUC-Mdo-062754	Monodelphis domestica	74.55	0.00e+00	1922.00
IUUC-Mmu-063943	Mus musculus	87.60	0.00e+00	2400.00
IUUC-Mpu-066800	Mustela putorius furo	87.64	0.00e+00	2345.00
IUUC-Mlu-067109	Myotis lucifugus	96.43	0.00e+00	1612.00
IUUC-Nfi-068430	Neosartorya fischeri	29.68	3.00e-128	454.00
IUUC-Ncr-068763	Neurospora crassa	30.49	6.00e-106	379.00
IUUC-Nle-069569	Nomascus leucogenys	88.66	0.00e+00	2269.00
IUUC-Ont-072274	Oreochromis niloticus	62.69	0.00e+00	1704.00
IUUC-Oan-073160	Ornithorhynchus anatinus	80.97	0.00e+00	2048.00
IUUC-Ocu-074440	Oryctolagus cuniculus	96.67	0.00e+00	1617.00
IUUC-Oin-079273	Oryza indica	37.84	8.00e-14	69.70
IUUC-Ola-087059	Oryzias latipes	63.88	0.00e+00	1320.00
IUUC-Oga-088191	Otolemur garnettii	96.55	0.00e+00	1616.00
IUUC-Oar-090027	Ovis aries	96.57	0.00e+00	1617.00
IUUC-Ptr-091415	Pan troglodytes	87.74	0.00e+00	1462.00
IUUC-Pan-091829	Papio anubis	87.70	0.00e+00	2367.00
IUUC-Pma-094733	Petromyzon marinus	67.01	0.00e+00	1097.00
IUUC-Pfo-096645	Poecilia formosa	58.41	0.00e+00	1673.00
IUUC-Pab-097582	Pongo abelii	91.02	0.00e+00	2181.00
IUUC-Pca-100446	Procavia capensis	87.45	0.00e+00	2364.00
IUUC-Pva-102553	Pteropus vampyrus	91.56	0.00e+00	1507.00
IUUC-Rno-105359	Rattus norvegicus	84.83	0.00e+00	1503.00
IUUC-Sha-106769	Sarcophilus harrisii	92.90	0.00e+00	1466.00
IUUC-Ssl-108489	Sclerotinia sclerotiorum	30.64	2.00e-109	391.00
IUUC-Stu-112523	Solanum tuberosum	52.94	3.00e-12	65.50
IUUC-Sre-115161	Sporisorium reilianum	32.72	4.00e-120	427.00
IUUC-Ssc-116354	Sus scrofa	89.32	0.00e+00	2443.00
IUUC-Tni-119920	Tetraodon nigroviridis	61.38	0.00e+00	1640.00
IUUC-Tca-121478	Theobroma cacao	32.42	3.00e-105	377.00
IUUC-Tre-122213	Trichoderma reesei	30.69	6.00e-106	379.00
IUUC-Tme-127087	Tuber melanosporum	31.98	1.00e-117	418.00
IUUC-Tbe-128040	Tupaia belangeri	99.61	0.00e+00	1015.00
IUUC-Ttr-128979	Tursiops truncatus	88.92	0.00e+00	2372.00
IUUC-Uma-129590	Ustilago maydis	32.80	6.00e-120	426.00
IUUC-Vpa-130433	Vicugna pacos	98.23	0.00e+00	1548.00
IUUC-Xtr-132324	Xenopus tropicalis	65.78	0.00e+00	1801.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence