iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002157

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase RNF182; RING finger protein 182; RING-type E3 ubiquitin transferase RNF182

Genbank Nucleotide ID

GL192549

Gene Name

RNF182; PANDA_005987

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000020297.1	ENSAMET00000022120.1	ENSAMEP00000021351.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.14	9.00e-104	374.00	IUUC-Hsa-046401

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway.

Protein Sequence
(Fasta)

MASQSPDEAA EAQVSDELEC KICYNRYNLK QRKPKVLECC HRVCAKCLYK IIDFGDSPQG 60
VIVCPFCRFE TCLPDEEVSS LPDDSNILVN LTCGGKGKKG LPENPTELLL TPKRLASLVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAGCC AGTCACCAGA CGAGGCGGCC GAGGCTCAGG TGTCCGACGA ACTCGAGTGT 60
AAGATCTGTT ACAACCGGTA TAATCTGAAA CAGAGGAAGC CCAAAGTGCT GGAGTGTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

KEGG

aml:100469497

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003754	Anas platyrhynchos	90.57	8.00e-106	375.00
IUUC-Aca-005163	Anolis carolinensis	87.80	2.00e-101	361.00
IUUC-Ame-010899	Astyanax mexicanus	53.57	5.00e-53	200.00
IUUC-Bta-012609	Bos taurus	90.36	7.00e-94	336.00
IUUC-Cja-019820	Callithrix jacchus	95.55	7.00e-106	376.00
IUUC-Cfa-020982	Canis familiaris	88.19	3.00e-54	203.00
IUUC-Cpo-021400	Cavia porcellus	94.67	4.00e-102	363.00
IUUC-Csa-023232	Chlorocebus sabaeus	93.93	8.00e-103	366.00
IUUC-Cho-024286	Choloepus hoffmanni	92.31	9.00e-101	359.00
IUUC-Dre-027461	Danio rerio	54.13	4.00e-40	157.00
IUUC-Dno-029613	Dasypus novemcinctus	90.43	2.00e-99	355.00
IUUC-Dor-030647	Dipodomys ordii	93.06	2.00e-100	358.00
IUUC-Eca-034110	Equus caballus	95.14	3.00e-104	370.00
IUUC-Eeu-034580	Erinaceus europaeus	95.55	2.00e-105	375.00
IUUC-Fca-036483	Felis catus	94.74	2.00e-104	371.00
IUUC-Fal-037213	Ficedula albicollis	88.93	8.00e-107	379.00
IUUC-Gmo-038766	Gadus morhua	50.56	1.00e-25	107.00
IUUC-Gga-041249	Gallus gallus	92.00	9.00e-98	349.00
IUUC-Gac-042045	Gasterosteus aculeatus	49.22	3.00e-55	208.00
IUUC-Ggo-045237	Gorilla gorilla	95.14	4.00e-105	373.00
IUUC-Hsa-046401	Homo sapiens	95.14	4.00e-105	373.00
IUUC-Itr-048794	Ictidomys tridecemlineatus	91.80	2.00e-99	355.00
IUUC-Lch-050274	Latimeria chalumnae	71.14	4.00e-85	307.00
IUUC-Loc-052382	Lepisosteus oculatus	58.54	5.00e-66	244.00
IUUC-Mcc-055173	Macaca mulatta	95.14	9.00e-105	372.00
IUUC-Meu-056310	Macropus eugenii	47.58	1.00e-48	185.00
IUUC-Mga-059578	Meleagris gallopavo	90.16	2.00e-104	371.00
IUUC-Mmr-060739	Microcebus murinus	95.14	2.00e-104	370.00
IUUC-Mdo-062765	Monodelphis domestica	90.28	5.00e-106	376.00
IUUC-Mmu-064145	Mus musculus	95.49	3.00e-103	367.00
IUUC-Mpu-066170	Mustela putorius furo	97.17	7.00e-107	379.00
IUUC-Mlu-067774	Myotis lucifugus	94.72	2.00e-115	407.00
IUUC-Nle-070141	Nomascus leucogenys	94.74	2.00e-104	371.00
IUUC-Opr-070247	Ochotona princeps	91.94	5.00e-105	373.00
IUUC-Ont-072312	Oreochromis niloticus	48.11	1.00e-58	219.00
IUUC-Oan-073640	Ornithorhynchus anatinus	85.19	1.00e-95	342.00
IUUC-Ocu-074191	Oryctolagus cuniculus	94.33	1.00e-103	368.00
IUUC-Ola-086432	Oryzias latipes	52.86	7.00e-57	213.00
IUUC-Oga-088498	Otolemur garnettii	96.36	1.00e-106	379.00
IUUC-Oar-089917	Ovis aries	92.77	5.00e-100	356.00
IUUC-Ptr-090460	Pan troglodytes	95.14	4.00e-105	373.00
IUUC-Pan-092766	Papio anubis	95.14	9.00e-105	372.00
IUUC-Psi-093943	Pelodiscus sinensis	88.93	2.00e-102	364.00
IUUC-Pfo-096878	Poecilia formosa	53.81	7.00e-59	220.00
IUUC-Pab-097922	Pongo abelii	94.74	5.00e-104	369.00
IUUC-Pca-100996	Procavia capensis	94.48	1.00e-54	205.00
IUUC-Pva-102313	Pteropus vampyrus	94.31	3.00e-115	407.00
IUUC-Rno-105963	Rattus norvegicus	95.90	2.00e-103	367.00
IUUC-Sha-106544	Sarcophilus harrisii	91.09	1.00e-107	382.00
IUUC-Sar-113158	Sorex araneus	39.29	1.00e-09	56.20
IUUC-Ssc-115614	Sus scrofa	93.93	8.00e-103	366.00
IUUC-Tgu-117096	Taeniopygia guttata	88.93	7.00e-107	379.00
IUUC-Tru-117656	Takifugu rubripes	48.43	2.00e-39	155.00
IUUC-Tsy-119244	Tarsius syrichta	95.14	9.00e-105	372.00
IUUC-Tni-120008	Tetraodon nigroviridis	42.42	2.00e-32	131.00
IUUC-Tbe-127391	Tupaia belangeri	96.36	3.00e-106	377.00
IUUC-Ttr-129115	Tursiops truncatus	93.12	4.00e-102	363.00
IUUC-Vpa-130722	Vicugna pacos	94.33	2.00e-103	368.00
IUUC-Xtr-131837	Xenopus tropicalis	81.82	2.00e-89	321.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence