iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020428

Ensembl Protein ID

ENSCAFP00000022395.3

UniProt Accession

E2RF98; E2RF98_CANLF

Genbank Protein ID

ENSCAFP00000022395

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014891

Gene Name

CRKL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000015188.3	ENSCAFT00000024123.3	ENSCAFP00000022395.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-19	69.5	124	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++e+v++lyd+ +++ ++L +kkG+++ +i  e+ +e W+++ ++ eg+ G++P  +vekl
   Q: 124  NLEYVRTLYDFLGNDAEDLPFKKGEILVII--EKPEEQWWSA-RNKEGRIGMIPVPYVEKL 181
           5789**************************..88999***99.6**************997 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSSARFDSSD RSAWYMGPVS RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH 60
YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPM GSVSAPNLPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTCCG CCAGGTTCGA CTCCTCAGAC CGCTCCGCCT GGTACATGGG GCCGGTGTCT 60
CGCCAGGAGG CGCAGACCCG GCTGCAGGGC CAGCGCCACG GAATGTTCCT AGTTCGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0003723--F:RNA binding
GO:0009887--P:animal organ morphogenesis
GO:0009952--P:anterior/posterior pattern specification
GO:0001568--P:blood vessel development
GO:0007507--P:heart development
GO:0060017--P:parathyroid gland development
GO:0008284--P:positive regulation of cell proliferation
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0048538--P:thymus development

KEGG

cfa:608125

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002025	Ailuropoda melanoleuca	99.31	3.00e-173	600.00
IUUC-Apl-004166	Anas platyrhynchos	89.40	9.00e-158	548.00
IUUC-Aca-004695	Anolis carolinensis	52.54	5.00e-84	303.00
IUUC-Ame-011285	Astyanax mexicanus	79.80	2.00e-139	488.00
IUUC-Bta-013076	Bos taurus	79.39	1.00e-111	395.00
IUUC-Cja-019850	Callithrix jacchus	97.24	3.00e-170	590.00
IUUC-Cpo-022079	Cavia porcellus	97.24	2.00e-170	590.00
IUUC-Csa-023877	Chlorocebus sabaeus	96.90	4.00e-170	590.00
IUUC-Cin-025128	Ciona intestinalis	51.71	2.00e-81	295.00
IUUC-Csv-026340	Ciona savignyi	47.63	1.00e-70	259.00
IUUC-Dre-027833	Danio rerio	81.69	6.00e-136	476.00
IUUC-Dno-029510	Dasypus novemcinctus	96.21	1.00e-170	592.00
IUUC-Dor-030297	Dipodomys ordii	97.36	3.00e-176	610.00
IUUC-Dme-031600	Drosophila melanogaster	44.19	1.00e-69	256.00
IUUC-Eca-033810	Equus caballus	98.28	5.00e-172	596.00
IUUC-Fca-036412	Felis catus	99.31	3.00e-173	600.00
IUUC-Fal-037170	Ficedula albicollis	92.07	3.00e-153	533.00
IUUC-Gga-040733	Gallus gallus	92.41	2.00e-140	491.00
IUUC-Gac-042398	Gasterosteus aculeatus	80.77	6.00e-145	506.00
IUUC-Ggo-044447	Gorilla gorilla	95.98	9.00e-113	398.00
IUUC-Hsa-046989	Homo sapiens	97.24	2.00e-170	590.00
IUUC-Itr-048092	Ictidomys tridecemlineatus	98.62	4.00e-172	596.00
IUUC-Lch-050385	Latimeria chalumnae	60.20	5.00e-100	357.00
IUUC-Loc-052916	Lepisosteus oculatus	86.23	6.00e-150	523.00
IUUC-Laf-053545	Loxodonta africana	97.50	1.00e-114	404.00
IUUC-Mga-059586	Meleagris gallopavo	93.79	5.00e-154	536.00
IUUC-Mvi-060518	Microbotryum violaceum	36.07	4.00e-10	58.50
IUUC-Mdo-061868	Monodelphis domestica	90.00	2.00e-159	554.00
IUUC-Mmu-063179	Mus musculus	96.55	5.00e-170	589.00
IUUC-Mpu-065863	Mustela putorius furo	98.97	1.00e-172	598.00
IUUC-Mlu-067290	Myotis lucifugus	98.28	3.00e-172	597.00
IUUC-Nle-069118	Nomascus leucogenys	97.24	2.00e-170	590.00
IUUC-Opr-070565	Ochotona princeps	95.71	2.00e-173	601.00
IUUC-Ont-071608	Oreochromis niloticus	81.79	2.00e-148	518.00
IUUC-Oan-072801	Ornithorhynchus anatinus	88.45	2.00e-161	561.00
IUUC-Ocu-073759	Oryctolagus cuniculus	97.93	3.00e-171	593.00
IUUC-Ola-086748	Oryzias latipes	75.33	2.00e-124	438.00
IUUC-Oga-088248	Otolemur garnettii	98.62	5.00e-173	599.00
IUUC-Oar-089525	Ovis aries	75.77	2.00e-121	428.00
IUUC-Ptr-091553	Pan troglodytes	97.24	2.00e-170	590.00
IUUC-Pan-092639	Papio anubis	97.24	2.00e-170	590.00
IUUC-Psi-093546	Pelodiscus sinensis	87.73	3.00e-102	364.00
IUUC-Pma-094340	Petromyzon marinus	60.32	6.00e-104	370.00
IUUC-Pfo-096090	Poecilia formosa	82.03	2.00e-148	518.00
IUUC-Pab-097876	Pongo abelii	96.57	1.00e-134	471.00
IUUC-Pca-100447	Procavia capensis	98.28	2.00e-172	597.00
IUUC-Pva-102346	Pteropus vampyrus	98.62	1.00e-170	592.00
IUUC-Rno-106017	Rattus norvegicus	96.55	9.00e-170	588.00
IUUC-Sha-106511	Sarcophilus harrisii	90.21	8.00e-104	369.00
IUUC-Sar-113583	Sorex araneus	96.55	4.00e-170	590.00
IUUC-Sre-115190	Sporisorium reilianum	29.67	2.00e-09	58.20
IUUC-Ssc-115339	Sus scrofa	96.90	4.00e-169	587.00
IUUC-Tgu-116454	Taeniopygia guttata	92.31	8.00e-98	349.00
IUUC-Tru-118580	Takifugu rubripes	77.81	9.00e-139	486.00
IUUC-Tsy-119327	Tarsius syrichta	96.22	3.00e-167	580.00
IUUC-Tni-120626	Tetraodon nigroviridis	77.56	5.00e-139	486.00
IUUC-Ttr-128248	Tursiops truncatus	97.24	1.00e-170	591.00
IUUC-Xtr-132626	Xenopus tropicalis	87.46	3.00e-152	530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence