iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036745

Ensembl Protein ID

ENSFALP00000015126.1

UniProt Accession

U3KJC2; U3KJC2_FICAL

Genbank Protein ID

ENSFALP00000015126

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011853

Gene Name

TRIM32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000014511.1	ENSFALT00000015191.1	ENSFALP00000015126.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.0	18	62

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg...plvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iC+e+f ++   p++l CgH+++++Cl+k+     +s + +rCP C
   Q: 18   CPICMESFTEEhlrPKLLHCGHTICKQCLEKL---LANSINGIRCPFC 62
           ********776677999************888...66799******** PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MAAAPYLNSD ALREVLECPI CMESFTEEHL RPKLLHCGHT ICKQCLEKLL ANSINGIRCP 60
FCSKITRITS LAQLTDNLTV LKIIDTAGLG EVVGLLMCKV CGRRLPRHFC KSCSLVLCEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCCG CCCCTTATCT CAACTCGGAC GCGCTGCGAG AGGTCCTGGA GTGCCCCATC 60
TGCATGGAAT CCTTCACCGA GGAGCACCTG AGGCCCAAAC TCCTGCACTG TGGCCACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001258--NHL_repeat
IPR013017--NHL_repeat_subgr
IPR033569--TRIM32
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51125--NHL
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01436--NHL
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005863--C:striated muscle myosin thick filament
GO:0003723--F:RNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007014--P:actin ubiquitination
GO:0061564--P:axon development
GO:0045444--P:fat cell differentiation
GO:0045087--P:innate immune response
GO:0046716--P:muscle cell cellular homeostasis
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0045787--P:positive regulation of cell cycle
GO:0030307--P:positive regulation of cell growth
GO:0030335--P:positive regulation of cell migration
GO:1903886--P:positive regulation of chemokine (C-C motif) ligand 20 production
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1903883--P:positive regulation of interleukin-17-mediated signaling pathway
GO:0045666--P:positive regulation of neuron differentiation
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045732--P:positive regulation of protein catabolic process
GO:0045862--P:positive regulation of proteolysis
GO:0051155--P:positive regulation of striated muscle cell differentiation
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0034612--P:response to tumor necrosis factor
GO:0009411--P:response to UV
GO:0001894--P:tissue homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000568	Aegilops tauschii	36.51	7.00e-06	43.90
IUUC-Aml-001554	Ailuropoda melanoleuca	84.37	0.00e+00	1098.00
IUUC-Aca-004290	Anolis carolinensis	88.31	0.00e+00	1159.00
IUUC-Aly-006480	Arabidopsis lyrata	41.82	6.00e-09	57.40
IUUC-Ame-011474	Astyanax mexicanus	59.77	0.00e+00	824.00
IUUC-Bta-013335	Bos taurus	82.20	0.00e+00	1068.00
IUUC-Cja-019836	Callithrix jacchus	84.77	0.00e+00	1108.00
IUUC-Cfa-020126	Canis familiaris	84.37	0.00e+00	1099.00
IUUC-Cpo-021619	Cavia porcellus	84.62	0.00e+00	1107.00
IUUC-Csa-023381	Chlorocebus sabaeus	84.98	0.00e+00	1105.00
IUUC-Cho-024696	Choloepus hoffmanni	83.54	0.00e+00	1079.00
IUUC-Dre-028768	Danio rerio	62.78	0.00e+00	848.00
IUUC-Dno-029162	Dasypus novemcinctus	84.67	0.00e+00	1103.00
IUUC-Dor-030490	Dipodomys ordii	85.01	0.00e+00	1090.00
IUUC-Ete-032250	Echinops telfairi	80.34	0.00e+00	1034.00
IUUC-Eca-033392	Equus caballus	84.98	0.00e+00	1105.00
IUUC-Fca-035512	Felis catus	84.52	0.00e+00	1097.00
IUUC-Fox-038006	Fusarium oxysporum	42.86	1.00e-05	43.50
IUUC-Gmo-038737	Gadus morhua	57.51	0.00e+00	768.00
IUUC-Gga-040258	Gallus gallus	93.66	0.00e+00	1205.00
IUUC-Gac-041657	Gasterosteus aculeatus	59.28	0.00e+00	786.00
IUUC-Ggo-045473	Gorilla gorilla	85.14	0.00e+00	1107.00
IUUC-Hsa-046653	Homo sapiens	85.29	0.00e+00	1108.00
IUUC-Hvu-047109	Hordeum vulgare	38.10	5.00e-06	44.30
IUUC-Itr-048947	Ictidomys tridecemlineatus	85.23	0.00e+00	1113.00
IUUC-Lch-049791	Latimeria chalumnae	70.94	0.00e+00	935.00
IUUC-Loc-052573	Lepisosteus oculatus	66.25	0.00e+00	877.00
IUUC-Laf-054514	Loxodonta africana	84.37	0.00e+00	1102.00
IUUC-Mcc-055244	Macaca mulatta	84.98	0.00e+00	1105.00
IUUC-Meu-056655	Macropus eugenii	77.74	0.00e+00	1033.00
IUUC-Mtr-058731	Medicago truncatula	36.00	6.00e-11	62.00
IUUC-Mga-059343	Meleagris gallopavo	90.28	0.00e+00	1135.00
IUUC-Mmr-061774	Microcebus murinus	84.83	0.00e+00	1105.00
IUUC-Mmu-063743	Mus musculus	84.23	0.00e+00	1102.00
IUUC-Mpu-066801	Mustela putorius furo	84.83	0.00e+00	1104.00
IUUC-Nle-069880	Nomascus leucogenys	84.98	0.00e+00	1106.00
IUUC-Ont-071805	Oreochromis niloticus	58.70	0.00e+00	783.00
IUUC-Oan-073221	Ornithorhynchus anatinus	80.06	0.00e+00	998.00
IUUC-Ocu-074609	Oryctolagus cuniculus	84.52	0.00e+00	1077.00
IUUC-Olo-080692	Oryza longistaminata	38.10	2.00e-06	46.20
IUUC-Osa-086244	Oryza sativa	37.88	6.00e-08	51.60
IUUC-Oga-088597	Otolemur garnettii	85.29	0.00e+00	1110.00
IUUC-Oar-089322	Ovis aries	85.29	0.00e+00	692.00
IUUC-Ptr-091638	Pan troglodytes	85.14	0.00e+00	1107.00
IUUC-Pan-092001	Papio anubis	84.98	0.00e+00	1105.00
IUUC-Psi-093112	Pelodiscus sinensis	90.73	0.00e+00	1199.00
IUUC-Ppa-095766	Physcomitrella patens	39.19	1.00e-11	63.20
IUUC-Pfo-097226	Poecilia formosa	59.02	0.00e+00	805.00
IUUC-Pab-098115	Pongo abelii	85.14	0.00e+00	1107.00
IUUC-Pte-104037	Pyrenophora teres	36.54	8.00e-07	47.80
IUUC-Rno-104950	Rattus norvegicus	84.54	0.00e+00	1105.00
IUUC-Sha-106842	Sarcophilus harrisii	79.91	0.00e+00	1049.00
IUUC-Smo-109517	Selaginella moellendorffii	37.31	5.00e-10	55.10
IUUC-Sly-111188	Solanum lycopersicum	41.79	1.00e-07	50.10
IUUC-Stu-112246	Solanum tuberosum	42.62	2.00e-07	48.90
IUUC-Ssc-115577	Sus scrofa	84.67	0.00e+00	1101.00
IUUC-Tgu-116636	Taeniopygia guttata	98.92	0.00e+00	1273.00
IUUC-Tsy-119479	Tarsius syrichta	85.14	0.00e+00	1108.00
IUUC-Tni-120872	Tetraodon nigroviridis	57.10	0.00e+00	763.00
IUUC-Tae-125903	Triticum aestivum	36.51	6.00e-06	43.90
IUUC-Tur-126036	Triticum urartu	36.51	7.00e-06	43.90
IUUC-Ttr-129170	Tursiops truncatus	84.83	0.00e+00	1112.00
IUUC-Xtr-132839	Xenopus tropicalis	72.62	0.00e+00	977.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence