iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003182

Ensembl Protein ID

ENSAPLP00000016048.1

UniProt Accession

U3J970; U3J970_ANAPL

Genbank Protein ID

ENSAPLP00000016048

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01001259

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000016162.1	ENSAPLT00000016860.1	ENSAPLP00000016048.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-07	31.0	391	422
E3 activity/RING/RING	9.20e-06	25.8	139	183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
            +v+++++  +d +++ +G  +g+i+++Dlr+
   Q: 391  RPVWSCCWclDDtNYIYAGLVNGSIMIYDLRD 422
           68*******9888****************997 PP

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+e      ++ +  l+CgH+f  +C+++w     +  ++ +CP C+
   Q: 139  CAICFEQWtnagDHRLSALRCGHLFGYTCIERW-----LRGQAGKCPQCN 183
           ******99777633388899*************.....4555559****6 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

ARRQQSIGGS QRTVSARCRA SLVRFFQISM SQVQATTPAA RLEPSHVAGS NQEEGSPEME 60
LSGSASSASE EEEEEEAEAA APPSPAAQET PAAASSDGKC CVCLNKCLYI FILKSRSPLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCGCAGGC AGCAGAGCAT CGGGGGCTCC CAGAGGACGG TCAGTGCCAG GTAAAGCAGC 60
AATGATTTGT GCTGTGCTTC CTCGCTCCAG GGCTGTGGCC AAATTCTGAG CACCTCACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000799	Aegilops tauschii	43.18	2.00e-09	56.60
IUUC-Aml-001188	Ailuropoda melanoleuca	70.87	0.00e+00	767.00
IUUC-Atr-003034	Amborella trichopoda	29.64	3.00e-17	82.00
IUUC-Aca-004619	Anolis carolinensis	80.43	0.00e+00	868.00
IUUC-Aly-006391	Arabidopsis lyrata	25.25	1.00e-31	130.00
IUUC-Ath-007300	Arabidopsis thaliana	25.47	3.00e-34	139.00
IUUC-Ame-010890	Astyanax mexicanus	65.72	0.00e+00	684.00
IUUC-Bta-013051	Bos taurus	69.57	0.00e+00	755.00
IUUC-Bdi-014519	Brachypodium distachyon	25.68	2.00e-23	103.00
IUUC-Bol-015271	Brassica oleracea	27.92	4.00e-33	135.00
IUUC-Bra-017931	Brassica rapa	28.68	9.00e-33	134.00
IUUC-Cja-019240	Callithrix jacchus	60.97	0.00e+00	746.00
IUUC-Cfa-021010	Canis familiaris	70.31	0.00e+00	763.00
IUUC-Cpo-022308	Cavia porcellus	67.89	0.00e+00	720.00
IUUC-Csa-023501	Chlorocebus sabaeus	68.79	0.00e+00	741.00
IUUC-Cho-024900	Choloepus hoffmanni	60.30	0.00e+00	662.00
IUUC-Cin-025403	Ciona intestinalis	37.35	1.00e-93	337.00
IUUC-Csv-025819	Ciona savignyi	36.54	7.00e-44	169.00
IUUC-Cme-027123	Cyanidioschyzon merolae	24.57	2.00e-18	87.00
IUUC-Dre-028354	Danio rerio	60.29	7.00e-176	610.00
IUUC-Dno-029400	Dasypus novemcinctus	71.91	0.00e+00	768.00
IUUC-Dor-030320	Dipodomys ordii	62.65	0.00e+00	640.00
IUUC-Dme-031949	Drosophila melanogaster	26.20	2.00e-38	153.00
IUUC-Ete-032691	Echinops telfairi	59.57	3.00e-98	352.00
IUUC-Eca-034320	Equus caballus	62.00	0.00e+00	778.00
IUUC-Fca-035732	Felis catus	69.98	0.00e+00	759.00
IUUC-Fal-036648	Ficedula albicollis	91.63	0.00e+00	957.00
IUUC-Gmo-038609	Gadus morhua	61.05	7.00e-153	533.00
IUUC-Gga-040522	Gallus gallus	89.73	3.00e-140	491.00
IUUC-Gac-042318	Gasterosteus aculeatus	59.71	8.00e-148	516.00
IUUC-Gma-043184	Glycine max	42.17	2.00e-15	77.00
IUUC-Ggo-044464	Gorilla gorilla	69.13	0.00e+00	745.00
IUUC-Hsa-045991	Homo sapiens	69.38	0.00e+00	747.00
IUUC-Hvu-047705	Hordeum vulgare	27.58	5.00e-27	115.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	70.04	0.00e+00	765.00
IUUC-Lch-050112	Latimeria chalumnae	71.81	0.00e+00	747.00
IUUC-Lpe-051605	Leersia perrieri	25.86	4.00e-18	86.30
IUUC-Loc-052241	Lepisosteus oculatus	68.90	0.00e+00	693.00
IUUC-Laf-054559	Loxodonta africana	68.94	0.00e+00	669.00
IUUC-Mcc-055093	Macaca mulatta	68.99	0.00e+00	743.00
IUUC-Meu-056417	Macropus eugenii	66.99	0.00e+00	681.00
IUUC-Mtr-058533	Medicago truncatula	27.53	8.00e-33	134.00
IUUC-Mga-059498	Meleagris gallopavo	75.16	0.00e+00	893.00
IUUC-Mmr-061782	Microcebus murinus	69.07	0.00e+00	730.00
IUUC-Mdo-062053	Monodelphis domestica	74.00	0.00e+00	768.00
IUUC-Mmu-063352	Mus musculus	65.69	0.00e+00	708.00
IUUC-Mac-064582	Musa acuminata	27.75	2.00e-26	113.00
IUUC-Mpu-066087	Mustela putorius furo	70.82	0.00e+00	749.00
IUUC-Mlu-068147	Myotis lucifugus	68.47	0.00e+00	719.00
IUUC-Nle-069503	Nomascus leucogenys	64.92	0.00e+00	686.00
IUUC-Opr-070479	Ochotona princeps	64.31	0.00e+00	674.00
IUUC-Ont-071700	Oreochromis niloticus	61.74	0.00e+00	645.00
IUUC-Oan-073702	Ornithorhynchus anatinus	79.64	0.00e+00	821.00
IUUC-Ocu-074886	Oryctolagus cuniculus	68.85	0.00e+00	738.00
IUUC-Oba-075729	Oryza barthii	26.47	1.00e-29	124.00
IUUC-Obr-076562	Oryza brachyantha	27.42	1.00e-21	97.80
IUUC-Ogl-077615	Oryza glaberrima	26.47	1.00e-29	124.00
IUUC-Ogu-078921	Oryza glumaepatula	26.47	4.00e-30	125.00
IUUC-Oin-079250	Oryza indica	23.43	7.00e-19	88.20
IUUC-Olo-080758	Oryza longistaminata	25.60	1.00e-27	117.00
IUUC-Ome-081707	Oryza meridionalis	24.44	5.00e-22	99.00
IUUC-Oni-083006	Oryza nivara	26.47	7.00e-30	125.00
IUUC-Opu-083650	Oryza punctata	25.38	1.00e-27	117.00
IUUC-Oru-084924	Oryza rufipogon	26.53	1.00e-30	127.00
IUUC-Osa-085820	Oryza sativa	28.53	3.00e-29	122.00
IUUC-Ola-087229	Oryzias latipes	62.71	4.00e-154	536.00
IUUC-Oga-088243	Otolemur garnettii	70.23	0.00e+00	738.00
IUUC-Oar-089461	Ovis aries	70.23	0.00e+00	761.00
IUUC-Ptr-090527	Pan troglodytes	69.38	0.00e+00	741.00
IUUC-Pan-092431	Papio anubis	68.23	0.00e+00	667.00
IUUC-Psi-093156	Pelodiscus sinensis	84.05	0.00e+00	922.00
IUUC-Ppa-095305	Physcomitrella patens	38.58	2.00e-21	98.20
IUUC-Pfo-097065	Poecilia formosa	61.90	2.00e-178	618.00
IUUC-Pab-098272	Pongo abelii	69.19	0.00e+00	746.00
IUUC-Pop-099827	Populus trichocarpa	25.92	4.00e-31	129.00
IUUC-Pca-100713	Procavia capensis	54.57	0.00e+00	639.00
IUUC-Ppe-102103	Prunus persica	28.95	1.00e-32	134.00
IUUC-Pva-103133	Pteropus vampyrus	67.47	2.00e-171	595.00
IUUC-Pte-104191	Pyrenophora teres	38.20	1.00e-07	50.10
IUUC-Pyt-104734	Pyrenophora triticirepentis	48.00	2.00e-07	49.70
IUUC-Sha-107628	Sarcophilus harrisii	73.67	0.00e+00	778.00
IUUC-Sit-109891	Setaria italica	26.82	8.00e-29	121.00
IUUC-Sly-111779	Solanum lycopersicum	29.32	2.00e-31	130.00
IUUC-Stu-112817	Solanum tuberosum	41.13	5.00e-20	90.90
IUUC-Sar-113124	Sorex araneus	60.99	6.00e-143	501.00
IUUC-Sbi-114107	Sorghum bicolor	26.19	2.00e-29	123.00
IUUC-Ssc-115850	Sus scrofa	71.63	0.00e+00	751.00
IUUC-Tgu-117295	Taeniopygia guttata	90.35	0.00e+00	940.00
IUUC-Tru-117539	Takifugu rubripes	60.23	0.00e+00	633.00
IUUC-Tsy-118805	Tarsius syrichta	55.59	4.00e-88	318.00
IUUC-Tni-120274	Tetraodon nigroviridis	60.93	0.00e+00	630.00
IUUC-Tca-121162	Theobroma cacao	29.68	1.00e-33	137.00
IUUC-Tae-124822	Triticum aestivum	24.42	3.00e-28	119.00
IUUC-Tur-126768	Triticum urartu	34.58	2.00e-16	80.50
IUUC-Tbe-127884	Tupaia belangeri	77.10	5.00e-58	218.00
IUUC-Ttr-128665	Tursiops truncatus	70.24	8.00e-108	384.00
IUUC-Vpa-130385	Vicugna pacos	62.78	0.00e+00	761.00
IUUC-Vvi-131464	Vitis vinifera	27.16	9.00e-27	114.00
IUUC-Xtr-132015	Xenopus tropicalis	65.04	0.00e+00	773.00
IUUC-Xma-133109	Xiphophorus maculatus	62.12	3.00e-176	611.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence