iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Meu-056170

Ensembl Protein ID

ENSMEUP00000000593.1

UniProt Accession

M1KQ50; M1KQ50_MACEU

Genbank Protein ID

AGE97657.1

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

KC153241

Gene Name

LYN; LynB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMEUG00000000638.1	ENSMEUT00000000645.1	ENSMEUP00000000593.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.20e-18	64.2	130	187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +v +lydyea ++++L+++kGd++ v+   e+ ++W+k+++ l++k+G++P+n+v+k++
   Q: 130  DITVVALYDYEAIHKEDLSFRKGDQMMVL---EKHGEWWKAKSLLNKKEGFIPSNYVAKIN 187
           56899************************...999***********************997 PP

Organism

Macropus eugenii

Protein Sequence
(Fasta)

VPLWLPGAVL ELALKLWGCS RLSWPREERP PLNSWWASNS PFLSVSRSLL PSSLFPKPPW 60
ASPPCRLPHS GLKSPWSSSA PNFPNQEGNM GCIKSKRKDS STQDGIDLKT QPVLTPDSQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCCTCTCT GGCTGCCAGG GGCTGGGTGC TCGAGCTTGC CCTGAAACTC TGGGGCTGCT 60
CTAGACTTTT TCTTGGCCCA GGGAAGAGCG GCCACCCCTC AATTCCTGGT GGGCCTCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	78.32	0.00e+00	798.00
IUUC-Apl-004139	Anas platyrhynchos	73.50	0.00e+00	751.00
IUUC-Aca-004333	Anolis carolinensis	73.15	0.00e+00	744.00
IUUC-Ame-011257	Astyanax mexicanus	68.87	0.00e+00	655.00
IUUC-Bta-013257	Bos taurus	78.32	0.00e+00	802.00
IUUC-Cja-018827	Callithrix jacchus	78.12	0.00e+00	797.00
IUUC-Cfa-020816	Canis familiaris	78.32	0.00e+00	797.00
IUUC-Cpo-021423	Cavia porcellus	78.32	0.00e+00	795.00
IUUC-Csa-024244	Chlorocebus sabaeus	78.71	0.00e+00	801.00
IUUC-Dre-028518	Danio rerio	68.87	0.00e+00	661.00
IUUC-Dno-029322	Dasypus novemcinctus	79.30	0.00e+00	804.00
IUUC-Dor-030706	Dipodomys ordii	76.67	0.00e+00	763.00
IUUC-Eca-034193	Equus caballus	78.71	0.00e+00	800.00
IUUC-Fal-037273	Ficedula albicollis	74.37	0.00e+00	769.00
IUUC-Gga-040417	Gallus gallus	76.47	0.00e+00	763.00
IUUC-Ggo-045096	Gorilla gorilla	78.71	0.00e+00	803.00
IUUC-Hsa-046214	Homo sapiens	78.71	0.00e+00	803.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	78.71	0.00e+00	804.00
IUUC-Lch-049991	Latimeria chalumnae	68.74	0.00e+00	687.00
IUUC-Loc-052309	Lepisosteus oculatus	65.63	0.00e+00	673.00
IUUC-Laf-053568	Loxodonta africana	77.93	0.00e+00	794.00
IUUC-Mcc-054849	Macaca mulatta	78.71	0.00e+00	801.00
IUUC-Mmr-061519	Microcebus murinus	78.32	0.00e+00	799.00
IUUC-Mdo-062090	Monodelphis domestica	75.56	0.00e+00	760.00
IUUC-Mmu-063760	Mus musculus	78.12	0.00e+00	795.00
IUUC-Mpu-065677	Mustela putorius furo	78.12	0.00e+00	799.00
IUUC-Mlu-067386	Myotis lucifugus	77.93	0.00e+00	795.00
IUUC-Nle-069742	Nomascus leucogenys	78.52	0.00e+00	799.00
IUUC-Oan-073193	Ornithorhynchus anatinus	76.65	0.00e+00	790.00
IUUC-Ocu-074501	Oryctolagus cuniculus	78.91	0.00e+00	806.00
IUUC-Oga-088069	Otolemur garnettii	77.43	0.00e+00	795.00
IUUC-Oar-090091	Ovis aries	78.21	0.00e+00	803.00
IUUC-Ptr-091409	Pan troglodytes	78.71	0.00e+00	803.00
IUUC-Pan-092268	Papio anubis	78.12	0.00e+00	808.00
IUUC-Psi-093685	Pelodiscus sinensis	73.31	0.00e+00	748.00
IUUC-Pab-098601	Pongo abelii	78.71	0.00e+00	803.00
IUUC-Pva-102160	Pteropus vampyrus	71.95	0.00e+00	719.00
IUUC-Rno-105557	Rattus norvegicus	78.12	0.00e+00	799.00
IUUC-Sha-106643	Sarcophilus harrisii	78.60	0.00e+00	808.00
IUUC-Sar-113555	Sorex araneus	84.31	5.00e-148	516.00
IUUC-Ssc-116317	Sus scrofa	73.29	0.00e+00	736.00
IUUC-Tgu-116865	Taeniopygia guttata	74.27	0.00e+00	764.00
IUUC-Tsy-119440	Tarsius syrichta	78.56	0.00e+00	825.00
IUUC-Ttr-128481	Tursiops truncatus	75.51	0.00e+00	700.00
IUUC-Xtr-131907	Xenopus tropicalis	62.98	1.00e-179	622.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence