iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011332

Ensembl Protein ID

ENSAMXP00000013748.1

UniProt Accession

W5L1N6; W5L1N6_ASTMX

Genbank Protein ID

ENSAMXP00000013748

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01035012

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000013344.1	ENSAMXT00000013748.1	ENSAMXP00000013748.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-20	71.0	781	813
UBD/Beta-Prp	3.90e-44	151.2	416	698

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDl 30
           gH++ vt ++f  +d +l+++G+ D +++ W++
   Q: 781  GHSSHVTNVHFlfNDsHLVSTGGKDMSVMQWRV 813
           8************99788899**********96 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdls............. 82
           ++ +++ cv+fs++++  +tg  +g i vw   +      l   he+ v a+++ ++g +l++g++Dr i  wd +             
   Q: 416  EKPKFVLCVTFSENGD-AITGDSSGNILVWGKGSNRISLALqAAHESSVLALCMLRNG-TLLSGGKDRRITAWDGNyqkiqtveipevy 502
           44556667***99999.688999*********99999999989**************9.9*************55555999******** PP
   S: 83   ............................tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncv 143
                                       +g+ + + +gh+d+++ l+++p ++ +++ +hd+ + +wd ++ q l  t++ +d + +++
   Q: 503  gpirtvaegrgetvligttknyvlqgslDGEFTPITQGHTDELWGLAVHPLKHQFLTCGHDKLVCLWDCDQHQPLW-TKTMED-AAQSA 589
           ***************************************************************************8.777666.78999 PP
   S: 144  vvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksv 228
            +hp+g  ++ G+  +   + d +t++l++  t   ++++  +sf+++g++l+ gs+d+++ ++ ++    + + v ++ gh+++++ +
   Q: 590  GFHPSGATVAIGTQTGRWLVLDTETKDLVTMHTD-GNEQISVMSFSPDGNFLAIGSHDNYIYIYAVSengrKYSRVGKCSGHSSFITHL 677
           9****************************99997.99******************************86655555************** PP
   S: 229  rfspnderlvsgssDgsiriW 249
           + s ++++lvs s D  i  W
   Q: 678  DWSVDSQYLVSNSGDYEILYW 698
           *******************99 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

ISTGFWSFAE TRNLYICVCV YLYFLDDSAS AASSMEVTDR IASLEQRVQM QEDEIQLLKS 60
ALADVVRRLN ISEEQQALLN RKGPTKARPM IAALPLRPTV NNGTVLPKKT LPSPSGSKKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCTACTG GATTTTGGAG CTTTGCTGTG AGGATTTGAT TGCATTAAGA TGAGATAAGA 60
CAGTAGATAA GGTTTTTCCT TATTATTTAA GAGCTTGTGA GTTTCTAATA TATCTATTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036368--P:cone photoresponse recovery

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002077	Ailuropoda melanoleuca	74.97	0.00e+00	1263.00
IUUC-Apl-004179	Anas platyrhynchos	77.81	0.00e+00	1270.00
IUUC-Aca-004993	Anolis carolinensis	72.45	0.00e+00	1197.00
IUUC-Bta-013419	Bos taurus	65.19	0.00e+00	1030.00
IUUC-Cja-018976	Callithrix jacchus	76.35	0.00e+00	1271.00
IUUC-Cfa-021276	Canis familiaris	78.17	0.00e+00	1264.00
IUUC-Csa-023355	Chlorocebus sabaeus	75.97	0.00e+00	1253.00
IUUC-Cin-025784	Ciona intestinalis	55.78	0.00e+00	749.00
IUUC-Csv-026305	Ciona savignyi	49.36	0.00e+00	771.00
IUUC-Dre-028728	Danio rerio	87.88	0.00e+00	1437.00
IUUC-Dno-029055	Dasypus novemcinctus	75.98	0.00e+00	1280.00
IUUC-Dor-030628	Dipodomys ordii	75.86	0.00e+00	1241.00
IUUC-Dme-032093	Drosophila melanogaster	37.89	3.00e-119	423.00
IUUC-Eca-034266	Equus caballus	78.43	0.00e+00	1320.00
IUUC-Fca-035446	Felis catus	77.20	0.00e+00	1252.00
IUUC-Fal-036734	Ficedula albicollis	75.00	0.00e+00	1267.00
IUUC-Gmo-038689	Gadus morhua	78.53	0.00e+00	1310.00
IUUC-Gga-040934	Gallus gallus	78.48	0.00e+00	984.00
IUUC-Gac-042476	Gasterosteus aculeatus	80.64	0.00e+00	1337.00
IUUC-Ggo-044828	Gorilla gorilla	76.56	0.00e+00	1297.00
IUUC-Hsa-045664	Homo sapiens	76.85	0.00e+00	1296.00
IUUC-Lch-050508	Latimeria chalumnae	75.61	0.00e+00	1276.00
IUUC-Loc-052823	Lepisosteus oculatus	79.76	0.00e+00	1331.00
IUUC-Laf-054164	Loxodonta africana	75.22	0.00e+00	1194.00
IUUC-Mcc-055810	Macaca mulatta	74.09	0.00e+00	1239.00
IUUC-Mga-059405	Meleagris gallopavo	75.40	0.00e+00	1256.00
IUUC-Mmr-061144	Microcebus murinus	77.68	0.00e+00	1267.00
IUUC-Mdo-062834	Monodelphis domestica	75.61	0.00e+00	1273.00
IUUC-Mmu-063955	Mus musculus	77.81	0.00e+00	1263.00
IUUC-Mpu-066240	Mustela putorius furo	76.94	0.00e+00	1237.00
IUUC-Mlu-067847	Myotis lucifugus	74.75	0.00e+00	912.00
IUUC-Nle-069783	Nomascus leucogenys	76.51	0.00e+00	1281.00
IUUC-Opr-070409	Ochotona princeps	70.93	0.00e+00	1147.00
IUUC-Ont-072468	Oreochromis niloticus	82.19	0.00e+00	1360.00
IUUC-Oan-073315	Ornithorhynchus anatinus	76.00	0.00e+00	1252.00
IUUC-Ocu-074604	Oryctolagus cuniculus	76.33	0.00e+00	1042.00
IUUC-Ola-086734	Oryzias latipes	81.89	0.00e+00	1335.00
IUUC-Oga-089105	Otolemur garnettii	76.11	0.00e+00	1254.00
IUUC-Oar-090057	Ovis aries	77.96	0.00e+00	1290.00
IUUC-Ptr-091138	Pan troglodytes	76.97	0.00e+00	1297.00
IUUC-Pan-092691	Papio anubis	70.18	0.00e+00	1148.00
IUUC-Psi-093076	Pelodiscus sinensis	76.16	0.00e+00	1271.00
IUUC-Pfo-096794	Poecilia formosa	79.55	0.00e+00	1298.00
IUUC-Pab-097787	Pongo abelii	74.70	0.00e+00	1267.00
IUUC-Pva-102676	Pteropus vampyrus	75.40	0.00e+00	1243.00
IUUC-Rno-105971	Rattus norvegicus	67.83	0.00e+00	1071.00
IUUC-Sha-107530	Sarcophilus harrisii	78.22	0.00e+00	1270.00
IUUC-Tgu-117046	Taeniopygia guttata	77.58	0.00e+00	1251.00
IUUC-Tru-118596	Takifugu rubripes	79.27	0.00e+00	1313.00
IUUC-Tsy-119142	Tarsius syrichta	72.94	0.00e+00	920.00
IUUC-Tni-120377	Tetraodon nigroviridis	82.37	0.00e+00	1338.00
IUUC-Tbe-127916	Tupaia belangeri	63.51	0.00e+00	829.00
IUUC-Ttr-129042	Tursiops truncatus	76.60	0.00e+00	1291.00
IUUC-Xtr-132117	Xenopus tropicalis	74.94	0.00e+00	1236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence