iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115958

Ensembl Protein ID

ENSSSCP00000008695.2

UniProt Accession

F1SU21; F1SU21_PIG

Genbank Protein ID

ENSSSCP00000008695

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP104541

Gene Name

NCK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000008144.2	ENSSSCT00000008921.2	ENSSSCP00000008695.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.50e-46	153.9	197	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++vq+ly++++++++eL++ kG++++viek e+d +W+++ ++++g+ Gl+P+n+v+ l+
   Q: 197  LHVVQTLYPFSSVTEEELNFDKGETMEVIEKPENDPEWWRC-RNARGQVGLVPKNYVVVLS 256
           689**************************************.5**************9886 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANRTGY VPSNYVERKN 60
SLKKGSLVRN LKDTLGLGRT RRKTSARDAS PTPSTDAEFP ANGGGADRIY DLSIPAIVKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGAAG AAGTCATCGT GATAGCCAAG TGGGACTACA CGGCCCAGCA GGACCAGGAG 60
CTGGACATCA AGAAGAACGA GCGCCTGTGG CTGCTGGACG ACTCCAAGAC ATGGTGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR017304--NCK
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0012506--C:vesicle membrane
GO:0007015--P:actin filament organization
GO:0016477--P:cell migration
GO:0048013--P:ephrin receptor signaling pathway
GO:0030032--P:lamellipodium assembly
GO:1903912--P:negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:0033137--P:negative regulation of peptidyl-serine phosphorylation
GO:1903898--P:negative regulation of PERK-mediated unfolded protein response
GO:1990441--P:negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:0030838--P:positive regulation of actin filament polymerization
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0036493--P:positive regulation of translation in response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001404	Ailuropoda melanoleuca	87.82	2.00e-165	575.00
IUUC-Apl-003456	Anas platyrhynchos	83.33	6.00e-160	556.00
IUUC-Aca-005105	Anolis carolinensis	83.65	2.00e-161	561.00
IUUC-Bta-012424	Bos taurus	95.45	4.00e-161	560.00
IUUC-Cja-019898	Callithrix jacchus	87.82	2.00e-165	574.00
IUUC-Cfa-020830	Canis familiaris	88.46	7.00e-166	576.00
IUUC-Cpo-021487	Cavia porcellus	84.29	2.00e-149	521.00
IUUC-Csa-023693	Chlorocebus sabaeus	87.82	2.00e-165	574.00
IUUC-Dre-028334	Danio rerio	78.80	2.00e-145	508.00
IUUC-Dno-028973	Dasypus novemcinctus	86.22	4.00e-163	566.00
IUUC-Dor-031003	Dipodomys ordii	85.58	6.00e-152	530.00
IUUC-Ete-032792	Echinops telfairi	85.62	1.00e-163	568.00
IUUC-Eca-033656	Equus caballus	88.46	5.00e-166	576.00
IUUC-Eeu-035169	Erinaceus europaeus	83.05	9.00e-96	342.00
IUUC-Fca-036347	Felis catus	87.82	3.00e-165	573.00
IUUC-Fal-037095	Ficedula albicollis	83.01	5.00e-160	556.00
IUUC-Gga-040155	Gallus gallus	83.33	6.00e-160	556.00
IUUC-Ggo-044805	Gorilla gorilla	88.14	8.00e-166	575.00
IUUC-Hsa-046585	Homo sapiens	88.14	7.00e-166	576.00
IUUC-Itr-048887	Ictidomys tridecemlineatus	86.54	2.00e-157	548.00
IUUC-Lch-049795	Latimeria chalumnae	82.05	6.00e-156	543.00
IUUC-Loc-051985	Lepisosteus oculatus	80.77	2.00e-150	525.00
IUUC-Laf-054228	Loxodonta africana	85.58	2.00e-161	561.00
IUUC-Mcc-055402	Macaca mulatta	87.82	2.00e-165	574.00
IUUC-Mga-059374	Meleagris gallopavo	83.33	6.00e-160	556.00
IUUC-Mmr-061453	Microcebus murinus	87.82	5.00e-165	573.00
IUUC-Mdo-063080	Monodelphis domestica	83.65	1.00e-160	558.00
IUUC-Mmu-063529	Mus musculus	86.86	1.00e-157	548.00
IUUC-Mpu-066815	Mustela putorius furo	87.82	2.00e-165	575.00
IUUC-Nle-069371	Nomascus leucogenys	88.14	7.00e-166	576.00
IUUC-Opr-070948	Ochotona princeps	87.18	1.00e-159	555.00
IUUC-Oan-073304	Ornithorhynchus anatinus	80.25	3.00e-116	410.00
IUUC-Ocu-074783	Oryctolagus cuniculus	87.82	5.00e-159	553.00
IUUC-Opu-083278	Oryza punctata	42.11	1.60e-01	29.30
IUUC-Oga-088391	Otolemur garnettii	88.14	1.00e-160	558.00
IUUC-Oar-090025	Ovis aries	86.69	4.00e-141	493.00
IUUC-Ptr-090975	Pan troglodytes	88.14	7.00e-166	576.00
IUUC-Pan-092287	Papio anubis	87.82	2.00e-165	574.00
IUUC-Psi-093413	Pelodiscus sinensis	84.29	2.00e-161	561.00
IUUC-Pab-098756	Pongo abelii	88.14	7.00e-166	576.00
IUUC-Pca-100235	Procavia capensis	82.18	2.00e-136	478.00
IUUC-Pva-102294	Pteropus vampyrus	83.97	3.00e-155	540.00
IUUC-Rno-105090	Rattus norvegicus	86.86	1.00e-157	548.00
IUUC-Sha-107521	Sarcophilus harrisii	83.65	2.00e-161	561.00
IUUC-Sit-110528	Setaria italica	52.17	9.00e-01	27.30
IUUC-Sar-113697	Sorex araneus	86.08	7.00e-155	539.00
IUUC-Tgu-116559	Taeniopygia guttata	80.77	2.00e-152	531.00
IUUC-Tbe-127931	Tupaia belangeri	87.66	2.00e-164	571.00
IUUC-Ttr-128993	Tursiops truncatus	94.21	5.00e-157	546.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence