iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	41.0	553	590
ULD/UDP/UBQ/UBQ_PIM	1.20e-22	80.1	13	86

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 553  FQQQLEQLNSMGFvNREANLQALIATGGDINAAIERLL 590
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +++tvkt+k+ke e+ +  + +v+e+Ke+i+++++ +++q+ LI+aGkiLkD +tL+++gikdg +vhlv+k+++
   Q: 13   IRVTVKTPKDKE-EILICDQASVKEFKEEISRRFKAQQDQLVLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQ 86
           68**********.***********************************************************987 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAEPSGAETR PQIRVTVKTP KDKEEILICD QASVKEFKEE ISRRFKAQQD QLVLIFAGKI 60
LKDGDTLNQH GIKDGLTVHL VIKTPQKAQD PVTTTASSPS TPDSASAPST TPASPAAPVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGAGGAG CTGGGCGGGC TGGCGGGCGG CCGGGCGGCG GCATGGCGGA GCCGAGTGGG 60
GCTGAGACGA GGCCCCAGAT TCGGGTCACC GTCAAGACCC CCAAGGACAA GGAGGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005776--C:autophagosome
GO:0031597--C:cytosolic proteasome complex
GO:0005789--C:endoplasmic reticulum membrane
GO:0031595--C:nuclear proteasome complex
GO:1901097--P:negative regulation of autophagosome maturation
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

KEGG

rno:310633

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001730	Ailuropoda melanoleuca	85.81	3.00e-154	538.00
IUUC-Apl-004150	Anas platyrhynchos	85.14	1.00e-155	542.00
IUUC-Ani-009418	Aspergillus nidulans	38.10	4.00e-08	52.80
IUUC-Ame-011329	Astyanax mexicanus	71.79	1.00e-167	583.00
IUUC-Bta-012938	Bos taurus	92.02	2.00e-160	559.00
IUUC-Cja-018858	Callithrix jacchus	94.13	1.00e-166	579.00
IUUC-Cfa-020455	Canis familiaris	92.49	1.00e-164	573.00
IUUC-Cpo-021410	Cavia porcellus	82.58	0.00e+00	681.00
IUUC-Dre-028009	Danio rerio	71.36	2.00e-147	516.00
IUUC-Dno-029892	Dasypus novemcinctus	93.66	3.00e-160	558.00
IUUC-Ete-032486	Echinops telfairi	71.70	1.00e-166	579.00
IUUC-Eca-034284	Equus caballus	94.13	2.00e-164	572.00
IUUC-Fca-036145	Felis catus	77.62	2.00e-119	422.00
IUUC-Fal-037180	Ficedula albicollis	85.14	2.00e-153	535.00
IUUC-Gga-041050	Gallus gallus	85.38	3.00e-146	511.00
IUUC-Gac-041826	Gasterosteus aculeatus	71.73	1.00e-148	519.00
IUUC-Ggo-045480	Gorilla gorilla	90.85	5.00e-162	564.00
IUUC-Hsa-046554	Homo sapiens	94.13	6.00e-165	574.00
IUUC-Itr-048781	Ictidomys tridecemlineatus	93.66	1.00e-164	572.00
IUUC-Lch-049480	Latimeria chalumnae	78.33	9.00e-118	417.00
IUUC-Laf-054476	Loxodonta africana	93.43	8.00e-166	577.00
IUUC-Mcc-054765	Macaca mulatta	94.13	7.00e-165	573.00
IUUC-Meu-056843	Macropus eugenii	87.56	1.00e-162	566.00
IUUC-Mpo-057467	Magnaporthe poae	50.00	4.00e-07	46.60
IUUC-Mla-058987	Melampsora laricipopulina	53.49	3.00e-07	49.70
IUUC-Mga-059730	Meleagris gallopavo	85.38	2.00e-153	535.00
IUUC-Mvi-060466	Microbotryum violaceum	55.32	2.00e-08	53.50
IUUC-Mmr-061256	Microcebus murinus	94.37	1.00e-172	599.00
IUUC-Mdo-061917	Monodelphis domestica	88.68	1.00e-162	566.00
IUUC-Mmu-063397	Mus musculus	97.32	0.00e+00	829.00
IUUC-Mpu-066300	Mustela putorius furo	91.76	2.00e-167	582.00
IUUC-Mlu-067197	Myotis lucifugus	90.61	3.00e-159	555.00
IUUC-Opr-070323	Ochotona princeps	91.10	4.00e-165	574.00
IUUC-Ont-072038	Oreochromis niloticus	73.29	3.00e-149	521.00
IUUC-Ocu-074759	Oryctolagus cuniculus	93.19	3.00e-159	555.00
IUUC-Ola-086802	Oryzias latipes	67.27	5.00e-145	507.00
IUUC-Oga-088466	Otolemur garnettii	92.25	6.00e-161	560.00
IUUC-Oar-090375	Ovis aries	92.72	8.00e-161	560.00
IUUC-Ptr-091312	Pan troglodytes	94.13	7.00e-165	573.00
IUUC-Pan-092351	Papio anubis	94.13	7.00e-165	573.00
IUUC-Psi-093262	Pelodiscus sinensis	84.44	4.00e-159	554.00
IUUC-Pma-094727	Petromyzon marinus	40.14	1.00e-56	214.00
IUUC-Pfo-096638	Poecilia formosa	65.13	1.00e-177	616.00
IUUC-Pab-097627	Pongo abelii	92.96	1.00e-163	570.00
IUUC-Pop-099549	Populus trichocarpa	33.72	9.00e-49	187.00
IUUC-Pca-100181	Procavia capensis	87.04	8.00e-98	350.00
IUUC-Pva-102687	Pteropus vampyrus	80.05	4.00e-131	461.00
IUUC-Ptt-103817	Puccinia triticina	51.22	2.00e-06	46.60
IUUC-Sha-107346	Sarcophilus harrisii	87.29	2.00e-160	558.00
IUUC-Ssl-108425	Sclerotinia sclerotiorum	50.00	8.00e-07	47.80
IUUC-Ssc-116185	Sus scrofa	93.90	3.00e-161	561.00
IUUC-Tgu-116930	Taeniopygia guttata	85.14	2.00e-152	532.00
IUUC-Tru-118652	Takifugu rubripes	71.96	1.00e-146	513.00
IUUC-Tre-122085	Trichoderma reesei	48.84	3.00e-07	49.30
IUUC-Tvi-122381	Trichoderma virens	48.84	6.00e-07	48.50
IUUC-Ttr-128771	Tursiops truncatus	93.43	8.00e-165	573.00
IUUC-Vpa-130633	Vicugna pacos	73.74	3.00e-100	358.00
IUUC-Xtr-132978	Xenopus tropicalis	83.65	2.00e-118	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence