iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054120

UUCD1 version

UUC-LoA-00690

Ensembl Protein ID

ENSLAFP00000017748.2

UniProt Accession

G3TQD4; G3TQD4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005935.3	ENSLAFT00000021906.2	ENSLAFP00000017748.2
ENSLAFG00000005935.3	ENSLAFT00000005934.3	ENSLAFP00000004974.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-13	48.3	96	125

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           Htd v  l+f  s++ ++s+s D+t+k+W+
   Q: 96   HTDQVLHLSFshSGCQFASCSKDCTVKIWS 125
           9*********96559**************8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

GQNVTMDEGG APLLPDSLVY HIFLNLGPAD VLAAGLVCRQ WQAVSRDEFL WREQFYRYYQ 60
VARDVPRHPA ATSWYEEFRR LYDTVPCVEV QTLKEHTDQV LHLSFSHSGC QFASCSKDCT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGACAGAATG TCACGATGGA CGAGGGCGGC GCGCCCCTGC TCCCCGACAG CCTCGTCTAC 60
CATATCTTCC TGAACCTGGG CCCCGCAGAC GTGCTGGCCG CGGGCCTGGT GTGCCGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	86.69	0.00e+00	981.00
IUUC-Apl-003274	Anas platyrhynchos	78.46	0.00e+00	795.00
IUUC-Aca-004626	Anolis carolinensis	60.19	3.00e-98	351.00
IUUC-Ame-011823	Astyanax mexicanus	60.35	1.00e-179	622.00
IUUC-Bta-012523	Bos taurus	87.81	0.00e+00	990.00
IUUC-Cja-018729	Callithrix jacchus	89.44	0.00e+00	1032.00
IUUC-Cfa-020303	Canis familiaris	88.00	0.00e+00	1006.00
IUUC-Cpo-022134	Cavia porcellus	89.30	0.00e+00	1026.00
IUUC-Csa-023253	Chlorocebus sabaeus	88.91	0.00e+00	1029.00
IUUC-Cin-025742	Ciona intestinalis	34.68	2.00e-78	286.00
IUUC-Dre-027511	Danio rerio	67.60	0.00e+00	723.00
IUUC-Dno-029044	Dasypus novemcinctus	88.05	0.00e+00	996.00
IUUC-Dor-030565	Dipodomys ordii	87.74	0.00e+00	1007.00
IUUC-Dme-031713	Drosophila melanogaster	42.11	4.00e-130	458.00
IUUC-Eca-033709	Equus caballus	88.07	0.00e+00	988.00
IUUC-Eeu-035093	Erinaceus europaeus	92.27	5.00e-99	354.00
IUUC-Fca-035674	Felis catus	88.42	0.00e+00	981.00
IUUC-Fal-037104	Ficedula albicollis	73.38	0.00e+00	844.00
IUUC-Gmo-039041	Gadus morhua	62.95	0.00e+00	653.00
IUUC-Gga-041230	Gallus gallus	75.77	0.00e+00	883.00
IUUC-Gac-042594	Gasterosteus aculeatus	61.99	0.00e+00	662.00
IUUC-Ggo-044486	Gorilla gorilla	88.20	0.00e+00	996.00
IUUC-Hsa-045701	Homo sapiens	87.68	0.00e+00	992.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	89.18	0.00e+00	1031.00
IUUC-Kpa-049204	Komagataella pastoris	31.88	4.00e-06	46.60
IUUC-Lch-050058	Latimeria chalumnae	70.02	0.00e+00	832.00
IUUC-Loc-052525	Lepisosteus oculatus	70.18	0.00e+00	741.00
IUUC-Mcc-054915	Macaca mulatta	88.56	0.00e+00	1019.00
IUUC-Meu-056715	Macropus eugenii	77.41	0.00e+00	894.00
IUUC-Mga-059831	Meleagris gallopavo	75.67	0.00e+00	788.00
IUUC-Mvi-060236	Microbotryum violaceum	38.46	1.00e-08	55.80
IUUC-Mmr-060655	Microcebus murinus	89.81	0.00e+00	1033.00
IUUC-Mdo-062641	Monodelphis domestica	81.87	0.00e+00	943.00
IUUC-Mmu-063471	Mus musculus	87.65	0.00e+00	1007.00
IUUC-Mpu-066586	Mustela putorius furo	88.44	0.00e+00	981.00
IUUC-Nle-069429	Nomascus leucogenys	88.56	0.00e+00	1025.00
IUUC-Ont-071780	Oreochromis niloticus	66.61	0.00e+00	715.00
IUUC-Ola-086458	Oryzias latipes	67.13	0.00e+00	729.00
IUUC-Oga-088739	Otolemur garnettii	88.07	0.00e+00	1021.00
IUUC-Oar-089275	Ovis aries	93.02	3.00e-46	175.00
IUUC-Ptr-090716	Pan troglodytes	86.40	0.00e+00	811.00
IUUC-Pan-092182	Papio anubis	80.99	0.00e+00	897.00
IUUC-Psi-093449	Pelodiscus sinensis	75.72	0.00e+00	875.00
IUUC-Pma-094289	Petromyzon marinus	55.48	7.00e-173	600.00
IUUC-Pfo-096062	Poecilia formosa	65.64	0.00e+00	724.00
IUUC-Pab-098726	Pongo abelii	87.02	0.00e+00	988.00
IUUC-Pca-100163	Procavia capensis	90.58	2.00e-101	362.00
IUUC-Pva-103051	Pteropus vampyrus	83.57	1.00e-130	459.00
IUUC-Rno-105707	Rattus norvegicus	87.96	0.00e+00	994.00
IUUC-Sha-107074	Sarcophilus harrisii	83.06	0.00e+00	913.00
IUUC-Ssc-116020	Sus scrofa	85.19	0.00e+00	824.00
IUUC-Tgu-116683	Taeniopygia guttata	70.97	4.00e-103	367.00
IUUC-Tru-118143	Takifugu rubripes	66.32	0.00e+00	713.00
IUUC-Tni-120777	Tetraodon nigroviridis	66.26	0.00e+00	719.00
IUUC-Ttr-128439	Tursiops truncatus	87.85	0.00e+00	991.00
IUUC-Xtr-132774	Xenopus tropicalis	57.62	1.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence