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Tag Content
UUCD2 ID IUUC-Ssc-115870
UUCD1 version UUC-SuS-00870
Ensembl Protein ID ENSSSCP00000004695.2
UniProt Accession F1RXY2; F1RXY2_PIG
Genbank Protein ID ENSSSCP00000004695
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID CU041276
Gene Name USP45
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000004351.2 ENSSSCT00000004808.2 ENSSSCP00000004695.2
ENSSSCG00000004351.2 ENSSSCT00000030684.1 ENSSSCP00000026030.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.40e-85 286.5 191 815
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp.............kepkgellkslqklfeelwkskkkavsprellka 76
           +G++NlgNtC++N+v+Q L++   l+el++e k++ ++ +                ++ g+l+++l  +++++ +++k+  sp+ l+++
   Q: 191  KGITNLGNTCFFNAVMQNLAQSYILTELMNEIKEHGVKLRIVpsldsqldplvveLSSPGPLTSALFLFLHSMKETEKGPLSPKILFNQ 279
           59*****************************66666665544667777777777788888***************************** PP
   S: 77   lkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk......slisdlFqgqlksqikclec 159
           l+++a+ f++ +qqD+qE+l++lld++++e +k+ +  + +++++ ++++ d++ +kk k +       ++i+++F g+l+s+++c+ec
   Q: 280  LCQKAPGFKSLQQQDSQELLHYLLDAVRTEETKRIQAGILKAFNNPTTKTADDETRKKVKAYGregvkmNFIDRIFIGELTSTVMCEEC 368
           *******************************99788887777777777777774444444443455555******************** PP
   S: 160  dnvssreepfldlslpvpgkeetkke............................................................... 185
           +n+s+ ++pf+d+slp+ +++ +k+                                                                
   Q: 369  ANISTVKDPFIDISLPIIEERVSKPVllgrtskyrslqetdnsqysgsvtventqqpkatkkhspskdmnqlihgrkcirklssgddka 457
           *********************98777*************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 458  avmyqknenletdggsslfasvrstestltesptdgsekeaslsdssvdadseasesesapkqtlllrsgnsycvhtnghlrhpsesep 546
           ***************************************************************************************** PP
   S: 186  ...........................................................................slqdcLesftkeee 199
                                                                                      s+q+cL +ft+ e 
   Q: 547  paresdsgddgvaqavselrlssavagdgdfdrenpllnvsnnlcfsenkqmvpqgpqnafqtlsqsyittskecSIQSCLYQFTSMEL 635
           ***************************************************************************************** PP
   S: 200  legenkyycekckkkqe...................aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspe 269
           l g+nk+ ce+c++k++                   a+k+l ++ +P +LilhLkRf  ++++ s +k+n++v+fpl+Ldl+pfc+ ++
   Q: 636  LMGNNKLLCEHCTEKKQkyqketssaekkaegvytnARKQLLISAVPAILILHLKRF--HQAGLSLRKVNRHVDFPLTLDLAPFCSATC 722
           *************99999999999999999999999*********************..9999************************99 PP
   S: 270  ekqke..kkkYeLiavvvHsGslssGHYvayvkn..........................ekgkWllfdDskVtevkeeevleetgsta 330
           +++ +  k+ Y L++vv HsGs+++GHY+ayvk                           + g+W++++D++V++v+e++ l+   ++a
   Q: 723  KNVCVgdKVLYGLYGVVEHSGSMRGGHYTAYVKVrtpsrkllehitgkknipglkepdseSAGQWVHVSDTYVQVVPESRALS---AQA 808
           887657799*************************999999999999999999999988877888*******************...*** PP
   S: 331  YvlfYkr 337
           Y+lfY+r
   Q: 809  YLLFYER 815
           *****98 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
MRVKEPSKAL TEKAKRSKRP TIPHDEDSSD DIAVGFTCQH VSHAINVNHV KRAITENLWS 60
VCSECLKERR FSDGQPVLLS DIWLCLKCGF QGCGKNSESQ HSVKHFNSWR AELHCIIISL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115870|DUB,USP|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAACCTTTTC AGTAAATAAC AGATGCGGGT GAAAGAGCCA TCCAAAGCTT TAACTGAGAA 60
AGCCAAAAGA AGTAAAAGAC CTACTATACC TCATGATGAA GACTCTTCAG ATGACATTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115870|DUB,USP|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG ssc:100152458
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002331 Ailuropoda melanoleuca 75.76 0.00e+00 1154.00
IUUC-Apl-003512 Anas platyrhynchos 68.49 0.00e+00 1087.00
IUUC-Aca-004284 Anolis carolinensis 62.80 0.00e+00 981.00
IUUC-Ame-010735 Astyanax mexicanus 49.26 5.00e-106 377.00
IUUC-Bta-012880 Bos taurus 88.13 0.00e+00 1401.00
IUUC-Cja-019144 Callithrix jacchus 80.93 0.00e+00 1328.00
IUUC-Cfa-020971 Canis familiaris 78.76 0.00e+00 740.00
IUUC-Cpo-022497 Cavia porcellus 68.00 0.00e+00 1063.00
IUUC-Csa-023910 Chlorocebus sabaeus 80.26 0.00e+00 1224.00
IUUC-Cho-024358 Choloepus hoffmanni 63.37 5.00e-115 407.00
IUUC-Dre-028106 Danio rerio 53.59 0.00e+00 807.00
IUUC-Dno-029456 Dasypus novemcinctus 75.54 0.00e+00 719.00
IUUC-Dor-030438 Dipodomys ordii 65.12 0.00e+00 982.00
IUUC-Dme-031870 Drosophila melanogaster 50.00 3.00e-36 147.00
IUUC-Ete-032736 Echinops telfairi 65.48 0.00e+00 975.00
IUUC-Eca-034211 Equus caballus 85.94 0.00e+00 1416.00
IUUC-Eeu-034797 Erinaceus europaeus 79.08 3.00e-88 318.00
IUUC-Fca-035947 Felis catus 80.79 0.00e+00 1215.00
IUUC-Fal-037199 Ficedula albicollis 67.86 0.00e+00 946.00
IUUC-Gmo-039228 Gadus morhua 61.52 2.00e-142 499.00
IUUC-Gga-040823 Gallus gallus 66.54 0.00e+00 627.00
IUUC-Gac-042406 Gasterosteus aculeatus 53.86 0.00e+00 780.00
IUUC-Ggo-045402 Gorilla gorilla 81.81 0.00e+00 1321.00
IUUC-Hsa-046430 Homo sapiens 81.54 0.00e+00 1321.00
IUUC-Itr-048855 Ictidomys tridecemlineatus 81.85 0.00e+00 785.00
IUUC-Lch-049547 Latimeria chalumnae 58.35 0.00e+00 916.00
IUUC-Loc-052842 Lepisosteus oculatus 57.98 0.00e+00 905.00
IUUC-Laf-053988 Loxodonta africana 82.20 0.00e+00 1340.00
IUUC-Mcc-055491 Macaca mulatta 77.14 0.00e+00 1239.00
IUUC-Meu-056256 Macropus eugenii 64.70 0.00e+00 628.00
IUUC-Mla-059026 Melampsora laricipopulina 31.71 2.00e-17 84.00
IUUC-Mga-059833 Meleagris gallopavo 62.14 3.00e-180 624.00
IUUC-Mmr-060952 Microcebus murinus 80.56 0.00e+00 1284.00
IUUC-Mdo-062642 Monodelphis domestica 69.09 0.00e+00 1076.00
IUUC-Mmu-063945 Mus musculus 76.53 0.00e+00 1231.00
IUUC-Mac-064941 Musa acuminata 28.52 2.00e-50 194.00
IUUC-Mpu-065944 Mustela putorius furo 78.95 0.00e+00 1234.00
IUUC-Mlu-067049 Myotis lucifugus 83.39 0.00e+00 1331.00
IUUC-Nle-069828 Nomascus leucogenys 81.56 0.00e+00 1322.00
IUUC-Opr-070672 Ochotona princeps 67.84 2.00e-136 479.00
IUUC-Ont-072121 Oreochromis niloticus 61.48 6.00e-139 488.00
IUUC-Oan-073656 Ornithorhynchus anatinus 65.50 0.00e+00 1050.00
IUUC-Ocu-074323 Oryctolagus cuniculus 78.85 0.00e+00 1253.00
IUUC-Ola-087238 Oryzias latipes 53.70 0.00e+00 817.00
IUUC-Oga-088379 Otolemur garnettii 75.79 0.00e+00 1210.00
IUUC-Oar-089718 Ovis aries 87.42 0.00e+00 1384.00
IUUC-Ptr-091358 Pan troglodytes 81.91 0.00e+00 1326.00
IUUC-Pan-092023 Papio anubis 81.17 0.00e+00 1316.00
IUUC-Psi-093256 Pelodiscus sinensis 67.07 0.00e+00 1011.00
IUUC-Ppa-095584 Physcomitrella patens 29.31 2.00e-34 141.00
IUUC-Pfo-097285 Poecilia formosa 50.42 0.00e+00 724.00
IUUC-Pab-098539 Pongo abelii 81.66 0.00e+00 1321.00
IUUC-Pca-100610 Procavia capensis 67.53 0.00e+00 919.00
IUUC-Pva-102985 Pteropus vampyrus 80.17 0.00e+00 1287.00
IUUC-Rno-105538 Rattus norvegicus 75.92 0.00e+00 1222.00
IUUC-Sha-107022 Sarcophilus harrisii 69.93 8.00e-179 620.00
IUUC-Sja-107712 Schizosaccharomyces japonicus 28.38 1.00e-20 94.70
IUUC-Spo-108149 Schizosaccharomyces pombe 30.39 2.00e-20 94.70
IUUC-Sar-113637 Sorex araneus 73.11 0.00e+00 1105.00
IUUC-Tgu-116907 Taeniopygia guttata 68.17 0.00e+00 1083.00
IUUC-Tru-117835 Takifugu rubripes 49.41 0.00e+00 664.00
IUUC-Tsy-118869 Tarsius syrichta 79.78 0.00e+00 1139.00
IUUC-Tni-119716 Tetraodon nigroviridis 65.45 2.00e-95 343.00
IUUC-Tbe-128041 Tupaia belangeri 64.55 0.00e+00 940.00
IUUC-Ttr-128901 Tursiops truncatus 86.41 0.00e+00 1397.00
IUUC-Vpa-130331 Vicugna pacos 88.21 0.00e+00 1320.00
IUUC-Xtr-131794 Xenopus tropicalis 51.88 0.00e+00 774.00
Created Date 25-Jun-2017

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