iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034295

UUCD1 version

UUC-EqC-00890

Ensembl Protein ID

ENSECAP00000015986.1

UniProt Accession

F7DKI3; F7DKI3_HORSE

Protein Name

Uncharacterized protein

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018193.1	ENSECAT00000019525.1	ENSECAP00000015986.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	7.40e-06	25.9	54	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
           v++++  + t++  v  ++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++
   Q: 54   VEDAQMHVDTIWltVRADMTVASLKDMVFLDYGFPPTLQQWVI-GQRLaRDQETLHSHGVR 113
           6666655777777799999************************.55555*********995 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

AEEMALRLAR AVAGGDEQVA MQCATWLAEE RVPLIVQLKP EVSPTQDIRL WVSVEDAQMH 60
VDTIWLTVRA DMTVASLKDM VFLDYGFPPT LQQWVIGQRL ARDQETLHSH GVRRSGDSAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGAGGAGA TGGCCCTGAG ACTCGCCCGG GCAGTTGCGG GCGGGGATGA ACAGGTGGCT 60
ATGCAGTGTG CCACCTGGCT GGCAGAGGAA CGGGTGCCCC TGATTGTGCA GCTGAAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	76.94	0.00e+00	723.00
IUUC-Aca-004507	Anolis carolinensis	55.51	7.00e-135	473.00
IUUC-Ame-011008	Astyanax mexicanus	46.38	4.00e-123	434.00
IUUC-Bta-013247	Bos taurus	78.13	0.00e+00	727.00
IUUC-Cja-018880	Callithrix jacchus	77.14	0.00e+00	726.00
IUUC-Cfa-020477	Canis familiaris	77.93	0.00e+00	706.00
IUUC-Cpo-021558	Cavia porcellus	73.76	0.00e+00	686.00
IUUC-Csa-024129	Chlorocebus sabaeus	77.14	0.00e+00	721.00
IUUC-Cin-025630	Ciona intestinalis	51.60	1.00e-84	306.00
IUUC-Csv-026069	Ciona savignyi	51.60	7.00e-82	296.00
IUUC-Dre-027591	Danio rerio	64.73	2.00e-104	373.00
IUUC-Dno-029015	Dasypus novemcinctus	76.74	0.00e+00	717.00
IUUC-Dor-030313	Dipodomys ordii	91.47	2.00e-136	479.00
IUUC-Ete-032908	Echinops telfairi	65.48	7.00e-170	590.00
IUUC-Eeu-034454	Erinaceus europaeus	61.36	8.00e-76	277.00
IUUC-Fca-036380	Felis catus	77.93	0.00e+00	723.00
IUUC-Gmo-038561	Gadus morhua	50.59	4.00e-102	364.00
IUUC-Gac-041319	Gasterosteus aculeatus	47.70	3.00e-116	411.00
IUUC-Ggo-044456	Gorilla gorilla	50.00	3.00e-116	411.00
IUUC-Hsa-045738	Homo sapiens	77.53	0.00e+00	721.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	76.89	0.00e+00	694.00
IUUC-Lch-050269	Latimeria chalumnae	40.41	5.00e-96	345.00
IUUC-Loc-052776	Lepisosteus oculatus	47.48	2.00e-116	413.00
IUUC-Laf-054269	Loxodonta africana	74.16	0.00e+00	699.00
IUUC-Mcc-055669	Macaca mulatta	77.34	0.00e+00	721.00
IUUC-Mga-059615	Meleagris gallopavo	54.69	4.00e-17	79.00
IUUC-Mmr-061562	Microcebus murinus	76.11	0.00e+00	638.00
IUUC-Mdo-062263	Monodelphis domestica	67.58	0.00e+00	659.00
IUUC-Mmu-064325	Mus musculus	76.65	0.00e+00	700.00
IUUC-Mpu-066385	Mustela putorius furo	77.34	0.00e+00	723.00
IUUC-Mlu-067000	Myotis lucifugus	77.29	0.00e+00	709.00
IUUC-Nle-069812	Nomascus leucogenys	77.34	0.00e+00	714.00
IUUC-Opr-070575	Ochotona princeps	92.65	6.00e-108	384.00
IUUC-Ont-072405	Oreochromis niloticus	45.58	1.00e-121	429.00
IUUC-Ocu-074358	Oryctolagus cuniculus	68.49	0.00e+00	630.00
IUUC-Ola-086403	Oryzias latipes	47.40	3.00e-120	425.00
IUUC-Oga-087986	Otolemur garnettii	75.94	0.00e+00	714.00
IUUC-Oar-089600	Ovis aries	77.53	0.00e+00	725.00
IUUC-Ptr-091224	Pan troglodytes	77.34	0.00e+00	720.00
IUUC-Pan-092739	Papio anubis	77.53	0.00e+00	724.00
IUUC-Pma-094407	Petromyzon marinus	60.00	8.00e-94	337.00
IUUC-Pfo-096767	Poecilia formosa	45.15	7.00e-126	444.00
IUUC-Pab-098627	Pongo abelii	77.34	0.00e+00	714.00
IUUC-Pca-100641	Procavia capensis	76.05	0.00e+00	658.00
IUUC-Pva-102670	Pteropus vampyrus	77.14	0.00e+00	718.00
IUUC-Rno-105504	Rattus norvegicus	76.25	0.00e+00	694.00
IUUC-Sha-107342	Sarcophilus harrisii	67.78	0.00e+00	657.00
IUUC-Sar-113425	Sorex araneus	87.01	2.00e-116	412.00
IUUC-Ssc-115904	Sus scrofa	90.75	6.00e-95	339.00
IUUC-Tru-118096	Takifugu rubripes	47.24	1.00e-115	410.00
IUUC-Tni-120890	Tetraodon nigroviridis	49.00	4.00e-110	391.00
IUUC-Tbe-127578	Tupaia belangeri	74.64	1.00e-171	595.00
IUUC-Ttr-129107	Tursiops truncatus	77.93	0.00e+00	719.00
IUUC-Vpa-130353	Vicugna pacos	97.24	3.00e-80	291.00
IUUC-Xtr-132168	Xenopus tropicalis	36.96	1.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence