iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033944

UUCD1 version

UUC-EqC-00221

Ensembl Protein ID

ENSECAP00000011076.1

UniProt Accession

F6ZIS4; F6ZIS4_HORSE

Protein Name

Uncharacterized protein

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013147.1	ENSECAT00000013915.1	ENSECAP00000011076.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	28.70	7.00e-32	134.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	91.97	0.00e+00	820.00	IUUC-Hsa-046512
E3 adaptor/Cullin RING/SCF/F-box	57.18	1.00e-127	454.00	IUUC-Ots-000025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MHAFKTPESV DAMHRKHLQE IPDQSSNVTT SFTWGWDSSK TCELLSGMGV SALEKEEVDS 60
ENIPQELLSN LGHPQSPPRK RLKSKGNDKD FVIVRRPKLN RENFPGVSWD SLPDELLLGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGCAGAAG AGCCCTGCGC GCGCGGTGGG GATGAAACGT TGCTAGAGTT CGCGGGTCTT 60
GCAGCTGGAG GCCCGAGTAG CACGCTGTGA GCTGCTGCGC GCCAAAGCGG GAATCCGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ecb:100053697

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	97.41	0.00e+00	816.00
IUUC-Atr-002711	Amborella trichopoda	25.39	1.00e-10	62.40
IUUC-Apl-003453	Anas platyrhynchos	68.77	3.00e-121	427.00
IUUC-Aca-005185	Anolis carolinensis	63.15	6.00e-144	503.00
IUUC-Ame-010665	Astyanax mexicanus	46.06	1.00e-92	333.00
IUUC-Bta-013450	Bos taurus	94.58	0.00e+00	832.00
IUUC-Bra-016626	Brassica rapa	23.85	6.00e-11	63.20
IUUC-Cel-018410	Caenorhabditis elegans	28.83	6.00e-29	121.00
IUUC-Cja-019834	Callithrix jacchus	91.98	0.00e+00	803.00
IUUC-Cfa-020401	Canis familiaris	97.94	0.00e+00	873.00
IUUC-Cpo-022183	Cavia porcellus	91.98	0.00e+00	805.00
IUUC-Csa-023418	Chlorocebus sabaeus	92.69	0.00e+00	807.00
IUUC-Cho-024412	Choloepus hoffmanni	89.83	0.00e+00	639.00
IUUC-Cin-025248	Ciona intestinalis	32.01	1.00e-40	160.00
IUUC-Csv-026189	Ciona savignyi	34.24	5.00e-37	148.00
IUUC-Cme-027297	Cyanidioschyzon merolae	36.36	4.00e-06	46.20
IUUC-Dre-028032	Danio rerio	48.27	6.00e-106	377.00
IUUC-Dno-029222	Dasypus novemcinctus	92.66	0.00e+00	829.00
IUUC-Dor-030505	Dipodomys ordii	87.01	3.00e-175	607.00
IUUC-Dme-031972	Drosophila melanogaster	35.17	2.00e-53	203.00
IUUC-Ete-032234	Echinops telfairi	84.81	4.00e-119	421.00
IUUC-Eeu-035008	Erinaceus europaeus	75.91	2.00e-121	427.00
IUUC-Fca-035412	Felis catus	96.46	0.00e+00	840.00
IUUC-Fal-037337	Ficedula albicollis	63.98	4.00e-140	491.00
IUUC-Gmo-038934	Gadus morhua	44.36	6.00e-43	167.00
IUUC-Gga-041152	Gallus gallus	66.75	4.00e-161	561.00
IUUC-Gac-041819	Gasterosteus aculeatus	45.57	5.00e-80	291.00
IUUC-Ggo-045479	Gorilla gorilla	91.81	0.00e+00	667.00
IUUC-Hsa-046512	Homo sapiens	91.97	0.00e+00	820.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	94.35	0.00e+00	782.00
IUUC-Lch-050115	Latimeria chalumnae	59.67	8.00e-141	493.00
IUUC-Loc-052554	Lepisosteus oculatus	50.23	3.00e-109	388.00
IUUC-Laf-053563	Loxodonta africana	92.42	0.00e+00	763.00
IUUC-Mcc-055143	Macaca mulatta	92.65	0.00e+00	801.00
IUUC-Meu-056593	Macropus eugenii	57.22	1.00e-107	382.00
IUUC-Mga-060084	Meleagris gallopavo	59.39	2.00e-84	305.00
IUUC-Mmr-060660	Microcebus murinus	96.10	0.00e+00	858.00
IUUC-Mdo-062363	Monodelphis domestica	70.28	5.00e-163	566.00
IUUC-Mmu-063287	Mus musculus	85.38	0.00e+00	754.00
IUUC-Mpu-065791	Mustela putorius furo	97.02	0.00e+00	867.00
IUUC-Mlu-067714	Myotis lucifugus	92.24	0.00e+00	785.00
IUUC-Nle-069823	Nomascus leucogenys	93.40	0.00e+00	813.00
IUUC-Opr-071046	Ochotona princeps	74.61	2.00e-107	382.00
IUUC-Ont-071820	Oreochromis niloticus	46.61	1.00e-70	259.00
IUUC-Ocu-074868	Oryctolagus cuniculus	93.87	0.00e+00	818.00
IUUC-Ola-086608	Oryzias latipes	47.00	1.00e-77	283.00
IUUC-Oga-089044	Otolemur garnettii	95.28	0.00e+00	828.00
IUUC-Oar-089650	Ovis aries	94.27	0.00e+00	850.00
IUUC-Ptr-090743	Pan troglodytes	92.92	0.00e+00	809.00
IUUC-Pan-092501	Papio anubis	92.69	0.00e+00	806.00
IUUC-Psi-094032	Pelodiscus sinensis	68.25	1.00e-165	575.00
IUUC-Ppa-095537	Physcomitrella patens	25.42	4.00e-11	63.50
IUUC-Pfo-097279	Poecilia formosa	46.27	6.00e-66	244.00
IUUC-Pab-097821	Pongo abelii	92.66	0.00e+00	671.00
IUUC-Pca-100100	Procavia capensis	91.53	0.00e+00	625.00
IUUC-Pva-103181	Pteropus vampyrus	95.20	0.00e+00	666.00
IUUC-Rno-105091	Rattus norvegicus	87.20	0.00e+00	763.00
IUUC-Sha-107226	Sarcophilus harrisii	72.27	2.00e-172	598.00
IUUC-Ssc-115665	Sus scrofa	97.17	0.00e+00	846.00
IUUC-Tgu-116982	Taeniopygia guttata	63.59	2.00e-137	481.00
IUUC-Tru-118276	Takifugu rubripes	46.48	1.00e-75	276.00
IUUC-Tsy-119074	Tarsius syrichta	93.79	0.00e+00	681.00
IUUC-Tni-120702	Tetraodon nigroviridis	47.90	6.00e-52	197.00
IUUC-Tbe-127990	Tupaia belangeri	93.29	6.00e-163	566.00
IUUC-Ttr-128661	Tursiops truncatus	82.31	4.00e-120	424.00
IUUC-Vvi-131526	Vitis vinifera	26.49	6.00e-11	63.20
IUUC-Xtr-132166	Xenopus tropicalis	57.04	3.00e-128	451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence