iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132379

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 23

Genbank Nucleotide ID

AAMC01035826

Gene Name

klhl23

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000025400.2	ENSXETT00000040956.3	ENSXETP00000040956.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-16	60.4	36	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.00e-07	30.3	138	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+lv   ge f++hk+ Laa+S++F+ +f+ +++e+  k+ ++++++++  +  ll++ Yt ++++
   Q: 36   TDVTLVSSsGEIFRCHKAALAACSHYFKVMFTADMKEKS-KNQIKLSGIDHAILDSLLNYAYTAQIRI 102
           7******99****************************86.************************9976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhF 31
           Nclg+ +fA+ + cp L + a++ i + F
   Q: 138  NCLGMHSFAEFHVCPNLEKEARRLIVSRF 166
           **************************999 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSLKDQDDYC FVYNDASHHV DFLEAFRTFY KEGLFTDVTL VSSSGEIFRC HKAALAACSH 60
YFKVMFTADM KEKSKNQIKL SGIDHAILDS LLNYAYTAQI RITARNVQSL LQASDQLRFV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCACTGA AGGACCAGGA CGATTACTGC TTTGTTTACA ACGATGCCTC TCACCACGTG 60
GATTTCCTGG AGGCCTTTCG GACATTTTAC AAAGAAGGTC TGTTCACAGA TGTCACCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

xtr:100496894

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001639	Ailuropoda melanoleuca	70.84	0.00e+00	874.00
IUUC-Apl-003948	Anas platyrhynchos	70.39	0.00e+00	797.00
IUUC-Aca-005045	Anolis carolinensis	67.92	0.00e+00	855.00
IUUC-Afu-009006	Aspergillus fumigatus	22.39	2.00e-03	37.40
IUUC-Ame-011013	Astyanax mexicanus	59.54	0.00e+00	734.00
IUUC-Bta-013159	Bos taurus	70.66	0.00e+00	872.00
IUUC-Cja-018886	Callithrix jacchus	70.61	0.00e+00	875.00
IUUC-Cfa-020205	Canis familiaris	70.97	0.00e+00	879.00
IUUC-Cpo-022295	Cavia porcellus	70.61	0.00e+00	875.00
IUUC-Cho-025089	Choloepus hoffmanni	68.13	0.00e+00	693.00
IUUC-Dre-027681	Danio rerio	59.64	0.00e+00	738.00
IUUC-Dno-029078	Dasypus novemcinctus	68.35	0.00e+00	694.00
IUUC-Ete-033011	Echinops telfairi	62.32	0.00e+00	726.00
IUUC-Eca-033213	Equus caballus	70.97	0.00e+00	879.00
IUUC-Fca-035884	Felis catus	70.79	0.00e+00	876.00
IUUC-Fal-036897	Ficedula albicollis	68.54	0.00e+00	842.00
IUUC-Gmo-038594	Gadus morhua	55.16	0.00e+00	678.00
IUUC-Gga-040791	Gallus gallus	69.18	0.00e+00	851.00
IUUC-Gac-042512	Gasterosteus aculeatus	59.07	0.00e+00	725.00
IUUC-Ggo-044837	Gorilla gorilla	71.15	0.00e+00	879.00
IUUC-Hsa-046231	Homo sapiens	71.15	0.00e+00	880.00
IUUC-Itr-048084	Ictidomys tridecemlineatus	71.15	0.00e+00	877.00
IUUC-Lch-050412	Latimeria chalumnae	69.57	0.00e+00	853.00
IUUC-Loc-052033	Lepisosteus oculatus	66.84	0.00e+00	802.00
IUUC-Laf-053908	Loxodonta africana	71.68	0.00e+00	885.00
IUUC-Mcc-054734	Macaca mulatta	71.33	0.00e+00	882.00
IUUC-Meu-055982	Macropus eugenii	70.79	0.00e+00	882.00
IUUC-Mga-059670	Meleagris gallopavo	68.16	0.00e+00	836.00
IUUC-Mmr-060692	Microcebus murinus	70.97	0.00e+00	880.00
IUUC-Mdo-062419	Monodelphis domestica	71.33	0.00e+00	885.00
IUUC-Mmu-063752	Mus musculus	71.33	0.00e+00	877.00
IUUC-Mpu-066515	Mustela putorius furo	70.79	0.00e+00	877.00
IUUC-Mlu-068004	Myotis lucifugus	68.58	0.00e+00	851.00
IUUC-Nfi-068413	Neosartorya fischeri	21.61	1.00e-03	38.50
IUUC-Nle-069163	Nomascus leucogenys	71.15	0.00e+00	880.00
IUUC-Opr-070823	Ochotona princeps	68.13	0.00e+00	689.00
IUUC-Ont-071629	Oreochromis niloticus	59.43	0.00e+00	739.00
IUUC-Oan-072841	Ornithorhynchus anatinus	68.28	0.00e+00	855.00
IUUC-Ocu-074300	Oryctolagus cuniculus	70.97	0.00e+00	880.00
IUUC-Ola-087025	Oryzias latipes	56.94	0.00e+00	715.00
IUUC-Oga-088442	Otolemur garnettii	69.84	0.00e+00	835.00
IUUC-Oar-089237	Ovis aries	71.02	0.00e+00	875.00
IUUC-Ptr-091541	Pan troglodytes	71.33	0.00e+00	882.00
IUUC-Psi-093748	Pelodiscus sinensis	71.86	0.00e+00	886.00
IUUC-Pma-094302	Petromyzon marinus	44.32	6.00e-99	354.00
IUUC-Pfo-097039	Poecilia formosa	61.01	0.00e+00	719.00
IUUC-Pab-098280	Pongo abelii	70.97	0.00e+00	877.00
IUUC-Pca-100840	Procavia capensis	63.98	0.00e+00	767.00
IUUC-Pva-102152	Pteropus vampyrus	70.79	0.00e+00	874.00
IUUC-Rno-105710	Rattus norvegicus	70.14	0.00e+00	867.00
IUUC-Sha-106991	Sarcophilus harrisii	70.79	0.00e+00	882.00
IUUC-Smo-109101	Selaginella moellendorffii	27.01	4.00e-15	75.10
IUUC-Sar-112931	Sorex araneus	70.43	0.00e+00	875.00
IUUC-Ssc-116016	Sus scrofa	69.95	0.00e+00	866.00
IUUC-Tgu-116999	Taeniopygia guttata	68.64	0.00e+00	844.00
IUUC-Tsy-119071	Tarsius syrichta	70.97	0.00e+00	878.00
IUUC-Tni-120149	Tetraodon nigroviridis	55.34	0.00e+00	658.00
IUUC-Tbe-127651	Tupaia belangeri	70.97	0.00e+00	878.00
IUUC-Ttr-128402	Tursiops truncatus	71.15	0.00e+00	880.00
IUUC-Vpa-130186	Vicugna pacos	69.53	0.00e+00	859.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence