iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062667

UUCD1 version

UUC-MoD-00856

Ensembl Protein ID

ENSMODP00000035157.1

UniProt Accession

F7FDD3; F7FDD3_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000024689.1	ENSMODT00000036746.1	ENSMODP00000035157.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-18	67.2	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-08	33.6	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS +F+a+f+++l+es   + v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRSFPCHRAVLAASSCYFEAMFSHGLRESL-DDAVNFHDsLHPEVLELLLDFAYSSRIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L++   +++l hF+
   Q: 146  PSNCLGMMLLSDAHQCRRLYELSWRMCLVHFE 177
           89*****************************5 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSVSVHENRK SRTSTGSMNI TLFHKPSHPD CVLSHLNTLR KHRMFTDVTL WAGDRSFPCH 60
RAVLAASSCY FEAMFSHGLR ESLDDAVNFH DSLHPEVLEL LLDFAYSSRI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGTCA GCGTCCATGA GAACCGGAAG TCCAGGACAA GCACGGGCTC TATGAATATC 60
ACCCTTTTCC ACAAACCTTC CCACCCGGAC TGCGTCCTGT CCCACCTCAA CACCCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

mdo:100013826

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	93.21	0.00e+00	1156.00
IUUC-Apl-003543	Anas platyrhynchos	93.22	0.00e+00	1121.00
IUUC-Aca-004729	Anolis carolinensis	89.81	0.00e+00	1094.00
IUUC-Ame-011020	Astyanax mexicanus	87.27	0.00e+00	1055.00
IUUC-Bta-012955	Bos taurus	91.00	0.00e+00	1141.00
IUUC-Cja-018839	Callithrix jacchus	92.19	0.00e+00	1146.00
IUUC-Cfa-020224	Canis familiaris	93.21	0.00e+00	1159.00
IUUC-Cpo-021593	Cavia porcellus	89.13	0.00e+00	1074.00
IUUC-Csa-023276	Chlorocebus sabaeus	92.87	0.00e+00	1152.00
IUUC-Dre-028053	Danio rerio	87.44	0.00e+00	1031.00
IUUC-Dno-029287	Dasypus novemcinctus	91.17	0.00e+00	1139.00
IUUC-Dor-030908	Dipodomys ordii	84.21	0.00e+00	1027.00
IUUC-Fca-035897	Felis catus	93.04	0.00e+00	1154.00
IUUC-Fal-037036	Ficedula albicollis	93.38	0.00e+00	1126.00
IUUC-Gmo-039345	Gadus morhua	86.25	0.00e+00	1016.00
IUUC-Gga-040404	Gallus gallus	92.87	0.00e+00	1127.00
IUUC-Gac-042447	Gasterosteus aculeatus	86.42	0.00e+00	1031.00
IUUC-Ggo-045060	Gorilla gorilla	93.04	0.00e+00	1154.00
IUUC-Hsa-046494	Homo sapiens	93.21	0.00e+00	1155.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	93.72	0.00e+00	1164.00
IUUC-Lch-050211	Latimeria chalumnae	88.10	0.00e+00	1065.00
IUUC-Lpe-050853	Leersia perrieri	27.51	2.00e-06	47.00
IUUC-Loc-052578	Lepisosteus oculatus	86.08	0.00e+00	1050.00
IUUC-Laf-053498	Loxodonta africana	92.70	0.00e+00	1104.00
IUUC-Mcc-055033	Macaca mulatta	93.04	0.00e+00	1154.00
IUUC-Meu-056893	Macropus eugenii	98.98	0.00e+00	1217.00
IUUC-Mga-060025	Meleagris gallopavo	93.04	0.00e+00	1125.00
IUUC-Mmr-060658	Microcebus murinus	92.19	0.00e+00	1151.00
IUUC-Mmu-063125	Mus musculus	89.98	0.00e+00	1087.00
IUUC-Mpu-066209	Mustela putorius furo	92.70	0.00e+00	1153.00
IUUC-Mlu-068237	Myotis lucifugus	89.98	0.00e+00	1097.00
IUUC-Nle-069454	Nomascus leucogenys	92.97	0.00e+00	1140.00
IUUC-Ont-072138	Oreochromis niloticus	86.93	0.00e+00	1023.00
IUUC-Oan-073320	Ornithorhynchus anatinus	86.93	0.00e+00	1088.00
IUUC-Ocu-073765	Oryctolagus cuniculus	86.93	0.00e+00	1063.00
IUUC-Oga-088002	Otolemur garnettii	92.19	0.00e+00	1145.00
IUUC-Oar-089481	Ovis aries	90.49	0.00e+00	1137.00
IUUC-Ptr-091200	Pan troglodytes	93.04	0.00e+00	1151.00
IUUC-Psi-093884	Pelodiscus sinensis	93.38	0.00e+00	1120.00
IUUC-Pva-102321	Pteropus vampyrus	92.36	0.00e+00	1152.00
IUUC-Rno-104835	Rattus norvegicus	90.15	0.00e+00	1089.00
IUUC-Sha-107528	Sarcophilus harrisii	98.98	0.00e+00	1218.00
IUUC-Ssc-116161	Sus scrofa	92.36	0.00e+00	1146.00
IUUC-Tgu-116569	Taeniopygia guttata	93.21	0.00e+00	1122.00
IUUC-Tni-120525	Tetraodon nigroviridis	77.33	0.00e+00	899.00
IUUC-Ttr-129297	Tursiops truncatus	92.36	0.00e+00	1151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence