iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054196

Ensembl Protein ID

ENSLAFP00000026912.1

UniProt Accession

G3UGF4; G3UGF4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005561.3	ENSLAFT00000033457.1	ENSLAFP00000026912.1
ENSLAFG00000005561.3	ENSLAFT00000005565.3	ENSLAFP00000004669.3
ENSLAFG00000005561.3	ENSLAFT00000036901.1	ENSLAFP00000025955.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-14	52.9	186	240

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 186  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGRTGWFPSNYVREIK 240
           68999*********************7..999*******..8**************997 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MQSRMWLSPC SCPESCVELQ SSAMNPEERI VTWLISLGVL DSPKKTICDP EEFLKSSLKN 60
GVVLCKLINR LVPGSVEKYC LEPQTEADCT NNINDFLKGC ATLQVEVFDP EDLYLGVNFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAATCGC GGATGTGGCT TAGTCCTTGC AGCTGCCCCG GAGAGCTGTG TGGAGCTTAC 60
AGTCCTCAGC AATGAATCCA GAAGAGAGAA TCGTGACATG GCTTATCTCT CTGGGAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	85.96	0.00e+00	1147.00
IUUC-Apl-003960	Anas platyrhynchos	75.48	0.00e+00	1107.00
IUUC-Aca-004988	Anolis carolinensis	69.88	0.00e+00	1013.00
IUUC-Aly-005591	Arabidopsis lyrata	38.71	7.00e-09	54.70
IUUC-Ame-011546	Astyanax mexicanus	62.82	0.00e+00	917.00
IUUC-Bta-013527	Bos taurus	91.48	0.00e+00	1353.00
IUUC-Cja-018935	Callithrix jacchus	91.48	0.00e+00	1323.00
IUUC-Cfa-021269	Canis familiaris	90.71	0.00e+00	1326.00
IUUC-Cpo-021620	Cavia porcellus	87.18	0.00e+00	1255.00
IUUC-Csa-023415	Chlorocebus sabaeus	92.52	0.00e+00	1338.00
IUUC-Dre-028580	Danio rerio	62.20	0.00e+00	931.00
IUUC-Dno-029201	Dasypus novemcinctus	87.42	0.00e+00	1347.00
IUUC-Dor-030868	Dipodomys ordii	72.39	0.00e+00	969.00
IUUC-Eca-033500	Equus caballus	92.39	0.00e+00	1331.00
IUUC-Eeu-035269	Erinaceus europaeus	82.18	3.00e-163	568.00
IUUC-Fca-035683	Felis catus	91.61	0.00e+00	1326.00
IUUC-Fal-037611	Ficedula albicollis	75.35	0.00e+00	1100.00
IUUC-Gmo-038980	Gadus morhua	60.78	0.00e+00	889.00
IUUC-Gga-040940	Gallus gallus	73.87	0.00e+00	1101.00
IUUC-Gac-042203	Gasterosteus aculeatus	59.21	0.00e+00	913.00
IUUC-Ggo-044755	Gorilla gorilla	92.39	0.00e+00	1335.00
IUUC-Hsa-046210	Homo sapiens	91.87	0.00e+00	1331.00
IUUC-Lch-049517	Latimeria chalumnae	68.59	0.00e+00	1009.00
IUUC-Loc-052393	Lepisosteus oculatus	63.04	0.00e+00	986.00
IUUC-Mcc-055716	Macaca mulatta	92.52	0.00e+00	1337.00
IUUC-Meu-056285	Macropus eugenii	74.24	0.00e+00	680.00
IUUC-Mtr-058576	Medicago truncatula	44.44	5.00e-11	61.60
IUUC-Mga-060029	Meleagris gallopavo	74.84	0.00e+00	1110.00
IUUC-Mmr-060803	Microcebus murinus	92.52	0.00e+00	1338.00
IUUC-Mdo-062654	Monodelphis domestica	79.15	0.00e+00	1177.00
IUUC-Mmu-063479	Mus musculus	88.79	0.00e+00	1322.00
IUUC-Mpu-066065	Mustela putorius furo	90.97	0.00e+00	1312.00
IUUC-Mlu-068222	Myotis lucifugus	89.82	0.00e+00	1288.00
IUUC-Nle-069379	Nomascus leucogenys	92.39	0.00e+00	1336.00
IUUC-Opr-070687	Ochotona princeps	73.45	0.00e+00	810.00
IUUC-Ont-072240	Oreochromis niloticus	58.94	0.00e+00	907.00
IUUC-Oan-073067	Ornithorhynchus anatinus	81.03	0.00e+00	1206.00
IUUC-Ocu-074852	Oryctolagus cuniculus	91.10	0.00e+00	1313.00
IUUC-Oga-089048	Otolemur garnettii	88.04	0.00e+00	1176.00
IUUC-Oar-089339	Ovis aries	90.86	0.00e+00	1380.00
IUUC-Pan-092666	Papio anubis	90.09	0.00e+00	1285.00
IUUC-Psi-093116	Pelodiscus sinensis	75.23	0.00e+00	1131.00
IUUC-Pfo-097394	Poecilia formosa	62.12	0.00e+00	912.00
IUUC-Pab-098567	Pongo abelii	92.39	0.00e+00	1337.00
IUUC-Pca-100997	Procavia capensis	80.91	0.00e+00	1102.00
IUUC-Pva-102500	Pteropus vampyrus	89.81	0.00e+00	1282.00
IUUC-Rno-104974	Rattus norvegicus	88.81	0.00e+00	1296.00
IUUC-Sar-113420	Sorex araneus	85.55	0.00e+00	1207.00
IUUC-Ssc-115679	Sus scrofa	91.17	0.00e+00	1165.00
IUUC-Tgu-117069	Taeniopygia guttata	74.84	0.00e+00	1105.00
IUUC-Tru-118488	Takifugu rubripes	56.20	0.00e+00	823.00
IUUC-Tsy-119243	Tarsius syrichta	82.34	0.00e+00	893.00
IUUC-Tni-120584	Tetraodon nigroviridis	60.15	0.00e+00	892.00
IUUC-Tbe-127994	Tupaia belangeri	75.78	0.00e+00	1072.00
IUUC-Ttr-128839	Tursiops truncatus	90.45	0.00e+00	1293.00
IUUC-Vpa-130144	Vicugna pacos	82.46	0.00e+00	1140.00
IUUC-Xtr-132624	Xenopus tropicalis	70.17	0.00e+00	1044.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence