• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046681
Ensembl Protein ID ENSP00000320092.5
UniProt Accession Q99963; O43553; O43554; SH3G3_HUMAN
Genbank Protein ID CAA67978.1; AAC04765.1; AAC04766.1; AAC04767.1; AAC04768.1
Protein Name Endophilin-A3; EEN-B2; Endophilin-3; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3
Genbank Nucleotide ID X99664; AF036269; AF036270; AF036271; AF036272
Gene Name SH3GL3; CNSA3; SH3D2C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000140600.16 ENST00000427482.6 ENSP00000391372.2
ENSG00000140600.16 ENST00000563901.5 ENSP00000456249.1
ENSG00000140600.16 ENST00000324537.5 ENSP00000320092.5
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircRNADbCircNetmiRTarBase
microRNATRANSFACmiRWalkRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.30e-13 51.5 297 350
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            ++ lyd+e++n++eL +k+Gd++++   ++ de+W +g    +g +G+fP n+ve +
   Q: 297  CCRGLYDFEPENQGELGFKEGDIITLT--NQIDENWYEG--MIHGESGFFPINYVEVI 350
           5889**********************7..99********..8*************976 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
 Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Protein Sequence
(Fasta)
MDGIFAGIIC NQANRCLTWT SQQLFSEKIS GAEGTKLDDE FLDMERKIDV TNKVVAEILS 60
KTTEYLQPNP AYRAKLGMLN TVSKIRGQVK TTGYPQTEGL LGDCMLKYGK ELGEDSTFGN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046681|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGCTCAAG TAGCCCAGGT CTCCACGCAA CAATGAAGCG TGGGCGGCCC CAGCAGCTTC 60
ATTTGCATAT CGCCGCGGCT TGGCCAATGG GCTGCGCAGG GGCTTTGGAA CGCAGTGTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046681|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR028501--Endophilin-A
IPR032469--Endophilin-A3_BAR
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS51021--BAR
PS50002--SH3
Pfam

PF03114--BAR
PF07653--SH3_2
PRINTS

PR00452--SH3DOMAIN
SMART

SM00721--BAR
SM00326--SH3
Gene Ontology

GO:0031901--C:early endosome membrane
GO:0070062--C:extracellular exosome
GO:0042802--F:identical protein binding
GO:0008289--F:lipid binding
GO:0007417--P:central nervous system development
GO:0006897--P:endocytosis
GO:0007165--P:signal transduction
KEGG hsa:6457
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001598 Ailuropoda melanoleuca 84.51 3.00e-173 600.00
IUUC-Apl-003422 Anas platyrhynchos 82.25 1.00e-157 549.00
IUUC-Ame-010779 Astyanax mexicanus 72.51 3.00e-152 531.00
IUUC-Bta-012748 Bos taurus 94.59 0.00e+00 635.00
IUUC-Cja-019400 Callithrix jacchus 97.61 0.00e+00 655.00
IUUC-Cfa-020979 Canis familiaris 91.67 1.00e-174 605.00
IUUC-Cpo-021364 Cavia porcellus 95.20 0.00e+00 630.00
IUUC-Csa-023447 Chlorocebus sabaeus 98.51 0.00e+00 630.00
IUUC-Cho-024825 Choloepus hoffmanni 78.61 1.00e-145 509.00
IUUC-Dre-028063 Danio rerio 75.59 2.00e-154 538.00
IUUC-Dno-029219 Dasypus novemcinctus 88.36 2.00e-167 581.00
IUUC-Dse-031165 Dothistroma septosporum 41.54 5.00e-12 67.40
IUUC-Dme-031633 Drosophila melanogaster 48.93 9.00e-97 347.00
IUUC-Ete-033094 Echinops telfairi 78.25 4.00e-147 514.00
IUUC-Eca-033209 Equus caballus 92.84 2.00e-180 625.00
IUUC-Fca-036354 Felis catus 85.71 1.00e-175 608.00
IUUC-Fal-037519 Ficedula albicollis 81.76 8.00e-147 513.00
IUUC-Gmo-038787 Gadus morhua 72.40 1.00e-146 512.00
IUUC-Gga-041064 Gallus gallus 81.52 1.00e-157 549.00
IUUC-Gac-042091 Gasterosteus aculeatus 73.59 4.00e-150 524.00
IUUC-Ggo-045608 Gorilla gorilla 79.29 6.00e-141 493.00
IUUC-Itr-048671 Ictidomys tridecemlineatus 94.93 0.00e+00 635.00
IUUC-Lch-050556 Latimeria chalumnae 68.83 1.00e-151 529.00
IUUC-Loc-052711 Lepisosteus oculatus 73.10 1.00e-158 552.00
IUUC-Laf-054427 Loxodonta africana 91.29 4.00e-168 583.00
IUUC-Mcc-055620 Macaca mulatta 98.21 0.00e+00 629.00
IUUC-Mor-056932 Magnaporthe oryzae 34.62 8.00e-13 70.10
IUUC-Mga-059193 Meleagris gallopavo 78.47 6.00e-156 543.00
IUUC-Mmr-060860 Microcebus murinus 79.33 2.00e-156 545.00
IUUC-Mmu-064365 Mus musculus 85.63 1.00e-168 585.00
IUUC-Mpu-066396 Mustela putorius furo 94.03 0.00e+00 636.00
IUUC-Nle-069316 Nomascus leucogenys 98.59 0.00e+00 701.00
IUUC-Opr-070964 Ochotona princeps 90.96 2.00e-174 604.00
IUUC-Ont-071397 Oreochromis niloticus 69.92 7.00e-149 520.00
IUUC-Oar-089220 Ovis aries 93.99 0.00e+00 628.00
IUUC-Ptr-090984 Pan troglodytes 99.72 0.00e+00 710.00
IUUC-Pan-092153 Papio anubis 98.51 0.00e+00 630.00
IUUC-Psi-093559 Pelodiscus sinensis 82.46 7.00e-161 560.00
IUUC-Pab-098780 Pongo abelii 84.34 3.00e-152 530.00
IUUC-Pva-103165 Pteropus vampyrus 76.20 4.00e-136 477.00
IUUC-Rno-104935 Rattus norvegicus 85.67 2.00e-169 587.00
IUUC-Sja-107704 Schizosaccharomyces japonicus 24.93 1.00e-11 64.70
IUUC-Spo-108224 Schizosaccharomyces pombe 26.70 2.00e-24 107.00
IUUC-Tsy-119366 Tarsius syrichta 94.94 0.00e+00 669.00
IUUC-Tbe-127252 Tupaia belangeri 75.73 1.00e-132 465.00
IUUC-Ttr-128272 Tursiops truncatus 86.88 5.00e-156 543.00
IUUC-Xtr-131882 Xenopus tropicalis 72.55 2.00e-152 532.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved