iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034234

UUCD1 version

UUC-EqC-00642

Ensembl Protein ID

ENSECAP00000004112.1

UniProt Accession

F7ABT5; F7ABT5_HORSE

Protein Name

Uncharacterized protein

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000004843.1	ENSECAT00000005839.1	ENSECAP00000004112.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.50	0.00e+00	903.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MTSFSTSAQC STSDSACRIS PEQINQVRPK LPLLKILQAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TASTDAAQTL 120

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Nucleotide Sequence
(Fasta)

TTAGATTTAT CAACAGACTG CAGCTTCTTC ACTGCCAAAA TGACATCATT TTCCACCTCT 60
GCCCAGTGTT CAACATCTGA CAGTGCTTGC AGGATCTCTC CAGAACAAAT CAATCAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	95.12	0.00e+00	842.00
IUUC-Apl-003800	Anas platyrhynchos	61.38	1.00e-159	556.00
IUUC-Aca-004608	Anolis carolinensis	58.12	5.00e-143	500.00
IUUC-Ame-010869	Astyanax mexicanus	46.67	7.00e-109	387.00
IUUC-Bta-013287	Bos taurus	92.06	0.00e+00	889.00
IUUC-Cja-019305	Callithrix jacchus	92.67	0.00e+00	834.00
IUUC-Cfa-020393	Canis familiaris	95.93	0.00e+00	865.00
IUUC-Cpo-022166	Cavia porcellus	89.70	0.00e+00	769.00
IUUC-Csa-023654	Chlorocebus sabaeus	94.30	0.00e+00	827.00
IUUC-Cho-024403	Choloepus hoffmanni	90.26	4.00e-130	457.00
IUUC-Cin-025448	Ciona intestinalis	28.70	1.00e-20	93.20
IUUC-Dre-027754	Danio rerio	48.42	4.00e-119	421.00
IUUC-Dno-029630	Dasypus novemcinctus	90.04	0.00e+00	861.00
IUUC-Dor-031064	Dipodomys ordii	69.86	0.00e+00	669.00
IUUC-Ete-032901	Echinops telfairi	80.89	0.00e+00	784.00
IUUC-Eeu-035015	Erinaceus europaeus	66.87	9.00e-170	589.00
IUUC-Fca-036587	Felis catus	95.93	0.00e+00	884.00
IUUC-Fal-036906	Ficedula albicollis	53.97	1.00e-139	489.00
IUUC-Gmo-038646	Gadus morhua	44.05	1.00e-97	350.00
IUUC-Gga-040124	Gallus gallus	58.94	4.00e-116	410.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.93	2.00e-108	385.00
IUUC-Ggo-045505	Gorilla gorilla	94.50	0.00e+00	848.00
IUUC-Hsa-046950	Homo sapiens	94.50	0.00e+00	849.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	91.65	0.00e+00	852.00
IUUC-Lch-050141	Latimeria chalumnae	53.69	1.00e-126	446.00
IUUC-Loc-051921	Lepisosteus oculatus	49.50	3.00e-116	411.00
IUUC-Laf-054281	Loxodonta africana	88.59	0.00e+00	806.00
IUUC-Mcc-055462	Macaca mulatta	90.45	0.00e+00	775.00
IUUC-Meu-056294	Macropus eugenii	74.67	6.00e-154	537.00
IUUC-Mga-059924	Meleagris gallopavo	60.65	2.00e-170	592.00
IUUC-Mmr-061428	Microcebus murinus	92.26	0.00e+00	876.00
IUUC-Mdo-062643	Monodelphis domestica	77.46	0.00e+00	749.00
IUUC-Mmu-063229	Mus musculus	83.71	0.00e+00	801.00
IUUC-Mpu-065782	Mustela putorius furo	93.10	0.00e+00	849.00
IUUC-Mlu-068105	Myotis lucifugus	83.13	0.00e+00	796.00
IUUC-Nle-069549	Nomascus leucogenys	94.91	0.00e+00	852.00
IUUC-Opr-070568	Ochotona princeps	90.75	0.00e+00	792.00
IUUC-Ont-072276	Oreochromis niloticus	46.81	2.00e-117	416.00
IUUC-Oan-072787	Ornithorhynchus anatinus	74.30	0.00e+00	674.00
IUUC-Ocu-074912	Oryctolagus cuniculus	91.65	0.00e+00	845.00
IUUC-Oba-075400	Oryza barthii	37.74	3.00e-06	46.60
IUUC-Oin-080213	Oryza indica	37.74	5.00e-06	46.60
IUUC-Olo-080683	Oryza longistaminata	37.74	3.00e-06	46.60
IUUC-Ome-081101	Oryza meridionalis	37.74	5.00e-06	46.60
IUUC-Oni-082539	Oryza nivara	37.74	5.00e-06	46.60
IUUC-Opu-083826	Oryza punctata	37.74	5.00e-06	46.60
IUUC-Oru-084786	Oryza rufipogon	37.74	3.00e-06	46.60
IUUC-Osa-085344	Oryza sativa	37.74	5.00e-06	46.60
IUUC-Ola-087037	Oryzias latipes	45.71	1.00e-98	353.00
IUUC-Oga-088953	Otolemur garnettii	88.69	0.00e+00	823.00
IUUC-Oar-089202	Ovis aries	92.46	0.00e+00	894.00
IUUC-Ptr-090964	Pan troglodytes	94.91	0.00e+00	853.00
IUUC-Pan-091975	Papio anubis	94.09	0.00e+00	842.00
IUUC-Psi-093558	Pelodiscus sinensis	62.73	8.00e-166	576.00
IUUC-Pfo-096454	Poecilia formosa	48.05	4.00e-114	404.00
IUUC-Pab-098123	Pongo abelii	94.70	0.00e+00	855.00
IUUC-Pca-101112	Procavia capensis	80.08	0.00e+00	751.00
IUUC-Pva-103098	Pteropus vampyrus	83.71	0.00e+00	793.00
IUUC-Rno-105930	Rattus norvegicus	84.35	0.00e+00	778.00
IUUC-Sha-107512	Sarcophilus harrisii	76.02	0.00e+00	666.00
IUUC-Smo-108729	Selaginella moellendorffii	47.22	3.00e-06	47.40
IUUC-Sit-110065	Setaria italica	41.18	1.00e-06	48.50
IUUC-Sly-111517	Solanum lycopersicum	36.54	4.00e-05	43.90
IUUC-Sar-113584	Sorex araneus	85.13	0.00e+00	749.00
IUUC-Sbi-113922	Sorghum bicolor	41.18	5.00e-06	46.60
IUUC-Tgu-116766	Taeniopygia guttata	55.76	1.00e-100	359.00
IUUC-Tru-117829	Takifugu rubripes	47.43	6.00e-115	407.00
IUUC-Tsy-119268	Tarsius syrichta	79.23	0.00e+00	701.00
IUUC-Tni-120204	Tetraodon nigroviridis	45.60	2.00e-108	385.00
IUUC-Tbe-127840	Tupaia belangeri	85.76	2.00e-128	452.00
IUUC-Ttr-128863	Tursiops truncatus	91.65	0.00e+00	864.00
IUUC-Vpa-130718	Vicugna pacos	95.05	0.00e+00	843.00
IUUC-Xtr-132320	Xenopus tropicalis	47.39	6.00e-93	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence