iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000012485.2	ENSMMUT00000017502.2	ENSMMUP00000016390.1
ENSMMUG00000012485.2	ENSMMUT00000064912.1	ENSMMUP00000054372.1
ENSMMUG00000012485.2	ENSMMUT00000059139.1	ENSMMUP00000046688.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-57	190.6	153	191
UBD/Beta-Prp	6.80e-72	243.3	25	235

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H ++v+c +f +d +l+vs+sdD+t+k+WD ++  +++s
   Q: 153  HINWVRCAKFsPDgRLIVSASDDKTVKLWDKSSRECVHS 191
           999********999****************999888875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           kg h + +tcv+fs ++++la+gs+d+++ vw +++++   ++ gh++++t+v+fsp+g +l++gs+D+t+++w ++      ++++h+
   Q: 25   KG-HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAITCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTAFRAHT 112
           44.5557777***999999*******************************************************8887677779999** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           ++v+s++f+ +g+++v++s+d+t++vw ++ ++ l   ls+h  +v+c++++pdg+l+vs+s+D+tv+lWd ++ ++++   + h + v
   Q: 113  ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLF-SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCE-HGGFV 199
           ***************************999999998.9*******************************************98.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           + ++f+++g++++++++d+tvk+wd++t + ++ l+
   Q: 200  TYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHLT 235
           ***************************999887765 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

ILQPCFTHLT LALLQEDPSL ERHFKGHRDA VTCVDFSINT KQLASGSMDS CLMVWHMKPQ 60
SRAYRFTGHK DAITCVNFSP SGHLLASGSR DKTVRIWVPN VKGESTAFRA HTATVRSVHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCATTTCC CAGCAGGCTG CGCTCGCCGT TAGAGTAGCC GGACGACGGG CTGGTGGGGT 60
GAACCCCTCA TCCTGGGTCT TTTAATTTCT CAGGCGGAAC GAGTGGCGGC AGACAGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	91.83	0.00e+00	759.00
IUUC-Apl-003466	Anas platyrhynchos	76.43	0.00e+00	639.00
IUUC-Aca-004323	Anolis carolinensis	69.23	3.00e-178	617.00
IUUC-Bta-012484	Bos taurus	91.13	0.00e+00	769.00
IUUC-Cja-019067	Callithrix jacchus	92.16	0.00e+00	796.00
IUUC-Cfa-020439	Canis familiaris	90.64	0.00e+00	764.00
IUUC-Cpo-021403	Cavia porcellus	88.28	0.00e+00	779.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	49.50	6.00e-109	387.00
IUUC-Csa-023479	Chlorocebus sabaeus	97.59	0.00e+00	716.00
IUUC-Cho-024354	Choloepus hoffmanni	87.61	2.00e-113	401.00
IUUC-Cin-025258	Ciona intestinalis	70.93	3.00e-139	488.00
IUUC-Csv-025955	Ciona savignyi	62.50	1.00e-143	502.00
IUUC-Dno-029467	Dasypus novemcinctus	77.89	3.00e-125	440.00
IUUC-Dor-030399	Dipodomys ordii	87.71	0.00e+00	748.00
IUUC-Eca-034425	Equus caballus	90.91	0.00e+00	756.00
IUUC-Eeu-034607	Erinaceus europaeus	79.31	9.00e-180	622.00
IUUC-Fca-035627	Felis catus	90.80	0.00e+00	755.00
IUUC-Fal-037381	Ficedula albicollis	72.68	1.00e-177	615.00
IUUC-Gmo-038489	Gadus morhua	66.92	2.00e-158	551.00
IUUC-Gga-040559	Gallus gallus	73.20	1.00e-174	605.00
IUUC-Gac-041453	Gasterosteus aculeatus	67.96	5.00e-168	583.00
IUUC-Ggo-044773	Gorilla gorilla	95.81	0.00e+00	765.00
IUUC-Hsa-045823	Homo sapiens	96.06	0.00e+00	768.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	91.65	0.00e+00	785.00
IUUC-Lch-050558	Latimeria chalumnae	67.87	7.00e-175	606.00
IUUC-Loc-052836	Lepisosteus oculatus	66.21	3.00e-173	601.00
IUUC-Laf-053974	Loxodonta africana	82.13	0.00e+00	666.00
IUUC-Meu-056646	Macropus eugenii	72.35	4.00e-123	434.00
IUUC-Mga-059295	Meleagris gallopavo	67.19	4.00e-171	594.00
IUUC-Mmr-061040	Microcebus murinus	91.87	0.00e+00	776.00
IUUC-Mdo-062519	Monodelphis domestica	75.47	5.00e-172	597.00
IUUC-Mmu-063759	Mus musculus	90.49	2.00e-167	582.00
IUUC-Mpu-066442	Mustela putorius furo	90.89	0.00e+00	744.00
IUUC-Mlu-068163	Myotis lucifugus	88.22	0.00e+00	756.00
IUUC-Nle-070160	Nomascus leucogenys	96.31	0.00e+00	769.00
IUUC-Opr-070192	Ochotona princeps	87.80	0.00e+00	655.00
IUUC-Ont-072539	Oreochromis niloticus	76.74	2.00e-145	508.00
IUUC-Oan-072834	Ornithorhynchus anatinus	60.65	7.00e-112	396.00
IUUC-Ocu-074624	Oryctolagus cuniculus	89.84	0.00e+00	699.00
IUUC-Ola-087268	Oryzias latipes	62.15	2.00e-156	545.00
IUUC-Oga-088964	Otolemur garnettii	85.02	0.00e+00	730.00
IUUC-Oar-090202	Ovis aries	90.67	0.00e+00	753.00
IUUC-Ptr-091164	Pan troglodytes	95.13	0.00e+00	771.00
IUUC-Pan-092805	Papio anubis	97.59	0.00e+00	716.00
IUUC-Psi-093359	Pelodiscus sinensis	78.30	3.00e-160	557.00
IUUC-Pma-094425	Petromyzon marinus	61.96	1.00e-161	562.00
IUUC-Pfo-096741	Poecilia formosa	72.43	3.00e-138	484.00
IUUC-Pab-098376	Pongo abelii	96.06	0.00e+00	810.00
IUUC-Pca-101122	Procavia capensis	87.44	0.00e+00	733.00
IUUC-Pva-103104	Pteropus vampyrus	70.44	2.00e-160	558.00
IUUC-Rno-105282	Rattus norvegicus	84.53	0.00e+00	650.00
IUUC-Sha-106840	Sarcophilus harrisii	84.30	6.00e-116	409.00
IUUC-Smo-108731	Selaginella moellendorffii	43.59	4.00e-75	274.00
IUUC-Sar-113262	Sorex araneus	62.56	3.00e-138	484.00
IUUC-Ssc-115392	Sus scrofa	90.72	0.00e+00	659.00
IUUC-Tgu-117340	Taeniopygia guttata	71.60	1.00e-173	602.00
IUUC-Tsy-119404	Tarsius syrichta	83.99	0.00e+00	705.00
IUUC-Tni-120713	Tetraodon nigroviridis	68.42	9.00e-135	473.00
IUUC-Tbe-127788	Tupaia belangeri	70.56	7.00e-152	530.00
IUUC-Ttr-128608	Tursiops truncatus	87.44	0.00e+00	695.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence